IL272962A - Use of gaboksadol for the treatment of anesthesia - Google Patents
Use of gaboksadol for the treatment of anesthesiaInfo
- Publication number
- IL272962A IL272962A IL272962A IL27296220A IL272962A IL 272962 A IL272962 A IL 272962A IL 272962 A IL272962 A IL 272962A IL 27296220 A IL27296220 A IL 27296220A IL 272962 A IL272962 A IL 272962A
- Authority
- IL
- Israel
- Prior art keywords
- gaboxadol
- narcolepsy
- treatment
- Prior art date
Links
- ZXRVKCBLGJOCEE-UHFFFAOYSA-N Gaboxadol Chemical compound C1NCCC2=C1ONC2=O ZXRVKCBLGJOCEE-UHFFFAOYSA-N 0.000 title 1
- 229950004346 gaboxadol Drugs 0.000 title 1
- 201000003631 narcolepsy Diseases 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pyrane Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762557412P | 2017-09-12 | 2017-09-12 | |
| PCT/US2018/050339 WO2019055369A1 (en) | 2017-09-12 | 2018-09-11 | USE OF GABOXADOL IN THE TREATMENT OF NARCOLEPSIA |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL272962A true IL272962A (en) | 2020-04-30 |
Family
ID=65630168
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL272962A IL272962A (en) | 2017-09-12 | 2020-02-27 | Use of gaboksadol for the treatment of anesthesia |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20190076409A1 (https=) |
| EP (1) | EP3661507A4 (https=) |
| JP (1) | JP2020533415A (https=) |
| KR (1) | KR20200053570A (https=) |
| CN (1) | CN111328282A (https=) |
| AU (1) | AU2018331326A1 (https=) |
| CA (1) | CA3075478A1 (https=) |
| IL (1) | IL272962A (https=) |
| MX (1) | MX2020002741A (https=) |
| WO (1) | WO2019055369A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111328282A (zh) * | 2017-09-12 | 2020-06-23 | 奥维德医疗公司 | 加波沙朵在治疗发作性睡病中的用途 |
| US11123332B2 (en) | 2018-11-21 | 2021-09-21 | Certego Therapeutics Inc. | Gaboxadol for reducing risk of suicide and rapid relief of depression |
| JP7709202B2 (ja) | 2019-06-28 | 2025-07-16 | ユニバーシティ オブ コペンハーゲン | 睡眠障害を伴うｃｎｓ障害の治療 |
| MX2022014599A (es) | 2020-05-20 | 2022-12-16 | Certego Therapeutics Inc | Gaboxadol deuterado en anillo y su uso para el tratamiento de trastornos psiquiatricos. |
| US20250375429A1 (en) | 2024-05-29 | 2025-12-11 | Smarter Not Harder, Inc. | Obligate pairing of orthosteric and non-orthosteric gaba ligands in pharmaceutical formulations |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200528098A (en) * | 2003-12-18 | 2005-09-01 | Lundbeck & Co As H | Treatment of insomnia in human patients |
| WO2005063248A1 (en) * | 2003-12-22 | 2005-07-14 | Sepracor Inc. | Modafinil combination therapy for improving sleep quality |
| US9480695B2 (en) * | 2011-09-29 | 2016-11-01 | The University Of Tokyo | Methods for inducing orexin neurons and agent for treating narcolepsy or eating disorder |
| US9050302B2 (en) * | 2013-03-01 | 2015-06-09 | Jazz Pharmaceuticals Ireland Limited | Method of administration of gamma hydroxybutyrate with monocarboxylate transporters |
| CA2905457A1 (en) * | 2013-03-13 | 2014-10-09 | Aerial Biopharma, Llc | Treatment of cataplexy |
| US9682069B2 (en) * | 2015-07-17 | 2017-06-20 | Ovid Therapeutics Inc | Methods of treating Dravet syndrome |
| KR20190013737A (ko) * | 2016-05-26 | 2019-02-11 | 오비드 테라퓨틱스 인크. | 피프라드롤을 이용한 행동 증후군들의 치료 방법들 |
| CN111328282A (zh) * | 2017-09-12 | 2020-06-23 | 奥维德医疗公司 | 加波沙朵在治疗发作性睡病中的用途 |
-
2018
- 2018-09-11 CN CN201880072667.9A patent/CN111328282A/zh active Pending
- 2018-09-11 EP EP18856943.8A patent/EP3661507A4/en not_active Withdrawn
- 2018-09-11 KR KR1020207010674A patent/KR20200053570A/ko not_active Withdrawn
- 2018-09-11 CA CA3075478A patent/CA3075478A1/en active Pending
- 2018-09-11 MX MX2020002741A patent/MX2020002741A/es unknown
- 2018-09-11 AU AU2018331326A patent/AU2018331326A1/en not_active Abandoned
- 2018-09-11 WO PCT/US2018/050339 patent/WO2019055369A1/en not_active Ceased
- 2018-09-11 US US16/127,375 patent/US20190076409A1/en not_active Abandoned
- 2018-09-11 JP JP2020536720A patent/JP2020533415A/ja active Pending
-
2020
- 2020-02-27 IL IL272962A patent/IL272962A/en unknown
- 2020-03-25 US US16/829,423 patent/US20200222372A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2018331326A1 (en) | 2020-03-19 |
| CA3075478A1 (en) | 2019-03-21 |
| CN111328282A (zh) | 2020-06-23 |
| US20200222372A1 (en) | 2020-07-16 |
| MX2020002741A (es) | 2020-07-21 |
| JP2020533415A (ja) | 2020-11-19 |
| WO2019055369A1 (en) | 2019-03-21 |
| EP3661507A1 (en) | 2020-06-10 |
| US20190076409A1 (en) | 2019-03-14 |
| KR20200053570A (ko) | 2020-05-18 |
| EP3661507A4 (en) | 2020-11-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL286316A (en) | New micro-dystrophins and related method of use | |
| GB201614522D0 (en) | Use of cannabinoids in the treatment of multiple myeloma | |
| IL259570A (en) | Combined therapy and their uses and methods | |
| GB201703115D0 (en) | Use of cannabinoids in the treatment of leukaemia | |
| GB201411496D0 (en) | Use of 7-Oh-Cannabidiol (7-Oh-CBD) and/or 7-Oh-Cannabidvarin (7-Oh-CBDV) in the treatment of epilepsy | |
| PL3134125T3 (pl) | Koniugat przeciwciało-lek i jego zastosowanie do leczenia raka | |
| IL264813B (en) | 2-oxo-imidazopyridines and their use | |
| IL268210A (en) | Use of gaboxadol in the treatment of tinnitus | |
| IL272962A (en) | Use of gaboksadol for the treatment of anesthesia | |
| GB201511382D0 (en) | Novel compounds and their use in therapy | |
| IL272414A (en) | Use of gaboksadol in the treatment of diabetes and related conditions | |
| PT3331610T (pt) | Agentes para utilização no tratamento de glioma | |
| GB201514021D0 (en) | Novel Pyridines and their use in the treatment of cancer | |
| LT3373922T (lt) | Kompozicijos ir būdai skirti naudoti homocistinurijos gydyme | |
| GB201511799D0 (en) | Composition and methods of treatment | |
| ZA202006886B (en) | R-fadrozole for use in the treatment of aldostonerism | |
| IL273543A (en) | A new treatment for SMA | |
| GB201605127D0 (en) | Composition and methods of treatment | |
| HUE044801T2 (hu) | Adelmidrol alkalmazása epitheliális mûködési zavarok kezelésében | |
| PT3548006T (pt) | Composição para utilização no tratamento de alterações intestinais | |
| GB201611936D0 (en) | Improved toenail treatment kit | |
| ZA201802201B (en) | Novel formulation and treatment methods | |
| SG10201500884WA (en) | Manufacture Of Vascular Smooth Muscle Cells And The Use | |
| GB201511772D0 (en) | Improvements in the treatment of ash | |
| GB201500278D0 (en) | Novel combination and use |