IL270749A - Novel use of a formyl peptide receptor 2/ lipoxin a4 receptor (fpr2/alx) agonist for treatment of heart failure - Google Patents
Novel use of a formyl peptide receptor 2/ lipoxin a4 receptor (fpr2/alx) agonist for treatment of heart failureInfo
- Publication number
- IL270749A IL270749A IL270749A IL27074919A IL270749A IL 270749 A IL270749 A IL 270749A IL 270749 A IL270749 A IL 270749A IL 27074919 A IL27074919 A IL 27074919A IL 270749 A IL270749 A IL 270749A
- Authority
- IL
- Israel
- Prior art keywords
- receptor
- fpr2
- lipoxin
- alx
- agonist
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Organic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762509489P | 2017-05-22 | 2017-05-22 | |
| PCT/US2018/033783 WO2018217684A1 (en) | 2017-05-22 | 2018-05-22 | Novel use of a formyl peptide receptor 2/ lipoxin a4 receptor (fpr2/alx) agonist for treatment of heart failure |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL270749A true IL270749A (en) | 2020-01-30 |
Family
ID=62567841
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL270749A IL270749A (en) | 2017-05-22 | 2019-11-18 | Novel use of a formyl peptide receptor 2/ lipoxin a4 receptor (fpr2/alx) agonist for treatment of heart failure |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20200069644A1 (en) |
| EP (1) | EP3630097A1 (en) |
| JP (1) | JP2020520948A (en) |
| KR (1) | KR20200006595A (en) |
| CN (1) | CN110662538A (en) |
| AU (1) | AU2018273382A1 (en) |
| BR (1) | BR112019024185A2 (en) |
| CA (1) | CA3064291A1 (en) |
| CL (1) | CL2019003325A1 (en) |
| CO (1) | CO2019013015A2 (en) |
| EA (1) | EA201992704A1 (en) |
| IL (1) | IL270749A (en) |
| MX (1) | MX2019013926A (en) |
| PE (1) | PE20200402A1 (en) |
| WO (1) | WO2018217684A1 (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110997652B (en) * | 2017-06-09 | 2023-02-28 | 百时美施贵宝公司 | Piperidinone formyl peptide 2 receptor agonists |
| CN116390913A (en) * | 2020-10-09 | 2023-07-04 | 百时美施贵宝公司 | Aminoimidazole FPR2 agonists |
| CN117503932B (en) * | 2022-07-30 | 2024-09-24 | 中国医学科学院阜外医院 | Use of Jun inhibitors for the preparation of a medicament for the treatment of heart failure with retained ejection fraction |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003082314A2 (en) * | 2002-04-03 | 2003-10-09 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with n-formyl peptide receptor like 1 (fprl1) |
| EA030474B1 (en) * | 2013-11-28 | 2018-08-31 | Киорин Фармасьютикал Ко., Лтд. | Urea derivatives or pharmacologically acceptable salts thereof |
| KR101645015B1 (en) * | 2014-03-11 | 2016-08-03 | 포항공과대학교 산학협력단 | Composition for treating insulin resistance-related disease comprising substance capable of activating FPR2 |
-
2018
- 2018-05-22 WO PCT/US2018/033783 patent/WO2018217684A1/en active Application Filing
- 2018-05-22 JP JP2019564446A patent/JP2020520948A/en active Pending
- 2018-05-22 CA CA3064291A patent/CA3064291A1/en active Pending
- 2018-05-22 BR BR112019024185-0A patent/BR112019024185A2/en not_active Application Discontinuation
- 2018-05-22 AU AU2018273382A patent/AU2018273382A1/en not_active Abandoned
- 2018-05-22 US US16/612,438 patent/US20200069644A1/en not_active Abandoned
- 2018-05-22 EA EA201992704A patent/EA201992704A1/en unknown
- 2018-05-22 KR KR1020197037388A patent/KR20200006595A/en not_active Application Discontinuation
- 2018-05-22 MX MX2019013926A patent/MX2019013926A/en unknown
- 2018-05-22 PE PE2019002437A patent/PE20200402A1/en unknown
- 2018-05-22 CN CN201880033663.XA patent/CN110662538A/en active Pending
- 2018-05-22 EP EP18730584.2A patent/EP3630097A1/en not_active Withdrawn
-
2019
- 2019-11-18 IL IL270749A patent/IL270749A/en unknown
- 2019-11-20 CL CL2019003325A patent/CL2019003325A1/en unknown
- 2019-11-21 CO CONC2019/0013015A patent/CO2019013015A2/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN110662538A (en) | 2020-01-07 |
| EP3630097A1 (en) | 2020-04-08 |
| CO2019013015A2 (en) | 2020-01-17 |
| AU2018273382A1 (en) | 2020-01-16 |
| PE20200402A1 (en) | 2020-02-26 |
| CL2019003325A1 (en) | 2020-04-17 |
| CA3064291A1 (en) | 2018-11-29 |
| US20200069644A1 (en) | 2020-03-05 |
| JP2020520948A (en) | 2020-07-16 |
| WO2018217684A1 (en) | 2018-11-29 |
| MX2019013926A (en) | 2020-01-20 |
| BR112019024185A2 (en) | 2020-06-02 |
| KR20200006595A (en) | 2020-01-20 |
| EA201992704A1 (en) | 2020-03-19 |
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