IL259358A - Bis-pyridazine compounds and their use in treating cancer - Google Patents

Bis-pyridazine compounds and their use in treating cancer

Info

Publication number
IL259358A
IL259358A IL259358A IL25935818A IL259358A IL 259358 A IL259358 A IL 259358A IL 259358 A IL259358 A IL 259358A IL 25935818 A IL25935818 A IL 25935818A IL 259358 A IL259358 A IL 259358A
Authority
IL
Israel
Prior art keywords
bis
treating cancer
pyridazine compounds
pyridazine
compounds
Prior art date
Application number
IL259358A
Other languages
English (en)
Hebrew (he)
Original Assignee
Astrazeneca Ab
Cancer Research Tech Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab, Cancer Research Tech Ltd filed Critical Astrazeneca Ab
Publication of IL259358A publication Critical patent/IL259358A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50Pyridazines; Hydrogenated pyridazines
    • A61K31/501Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL259358A 2015-11-27 2018-05-14 Bis-pyridazine compounds and their use in treating cancer IL259358A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1520959.6A GB201520959D0 (en) 2015-11-27 2015-11-27 Bis-pyridazine compounds and their use in treating cancer
PCT/EP2016/078899 WO2017089587A1 (en) 2015-11-27 2016-11-25 Bis-pyridazine compounds and their use in treating cancer

Publications (1)

Publication Number Publication Date
IL259358A true IL259358A (en) 2018-07-31

Family

ID=55177338

Family Applications (1)

Application Number Title Priority Date Filing Date
IL259358A IL259358A (en) 2015-11-27 2018-05-14 Bis-pyridazine compounds and their use in treating cancer

Country Status (17)

Country Link
US (2) US10196382B2 (cg-RX-API-DMAC7.html)
EP (1) EP3380468B8 (cg-RX-API-DMAC7.html)
JP (1) JP2018535226A (cg-RX-API-DMAC7.html)
KR (1) KR20180083426A (cg-RX-API-DMAC7.html)
CN (1) CN108349951B (cg-RX-API-DMAC7.html)
AR (1) AR106849A1 (cg-RX-API-DMAC7.html)
AU (1) AU2016360970B2 (cg-RX-API-DMAC7.html)
CA (1) CA3005102A1 (cg-RX-API-DMAC7.html)
DK (1) DK3380468T3 (cg-RX-API-DMAC7.html)
ES (1) ES2806723T3 (cg-RX-API-DMAC7.html)
GB (1) GB201520959D0 (cg-RX-API-DMAC7.html)
IL (1) IL259358A (cg-RX-API-DMAC7.html)
MX (1) MX2018006374A (cg-RX-API-DMAC7.html)
RU (1) RU2018122012A (cg-RX-API-DMAC7.html)
SG (1) SG11201803814SA (cg-RX-API-DMAC7.html)
TW (1) TW201731837A (cg-RX-API-DMAC7.html)
WO (1) WO2017089587A1 (cg-RX-API-DMAC7.html)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106552296B (zh) 2015-09-29 2020-08-14 上海氪励铵勤科技发展有限公司 纳米粒子、其制备方法与结石取出装置及应用
GB201520959D0 (en) 2015-11-27 2016-01-13 Astrazeneca Ab And Cancer Res Technology Ltd Bis-pyridazine compounds and their use in treating cancer
TW201733587A (zh) 2015-11-30 2017-10-01 阿斯特捷利康公司 1,3,4-噻二唑化合物及其在治療癌症中之用途
KR20250137464A (ko) 2024-03-11 2025-09-18 이석재 숏블라스트머신의 연마재탱크

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201402305WA (en) 2011-11-21 2014-06-27 Calithera Biosciences Inc Heterocyclic inhibitors of glutaminase
US9029531B2 (en) 2012-11-22 2015-05-12 Agios Pharmaceuticals, Inc. Compounds and their methods of use
CN105960405B (zh) 2014-01-06 2021-02-19 理森制药股份公司 谷氨酰胺酶抑制剂
GB201409624D0 (en) 2014-05-30 2014-07-16 Astrazeneca Ab 1,3,4-thiadiazole compounds and their use in treating cancer
GB201520959D0 (en) 2015-11-27 2016-01-13 Astrazeneca Ab And Cancer Res Technology Ltd Bis-pyridazine compounds and their use in treating cancer
TW201730188A (zh) 2015-11-30 2017-09-01 阿斯特捷利康公司 1,3,4-噻二唑化合物及其在治療癌症中之用途
TW201731511A (zh) 2015-11-30 2017-09-16 阿斯特捷利康公司 1,3,4-噻二唑化合物及其在治療癌症中之用途
TW201733587A (zh) 2015-11-30 2017-10-01 阿斯特捷利康公司 1,3,4-噻二唑化合物及其在治療癌症中之用途

Also Published As

Publication number Publication date
EP3380468A1 (en) 2018-10-03
SG11201803814SA (en) 2018-06-28
GB201520959D0 (en) 2016-01-13
AR106849A1 (es) 2018-02-21
US20190169172A1 (en) 2019-06-06
CA3005102A1 (en) 2017-06-01
US10577354B2 (en) 2020-03-03
EP3380468B8 (en) 2020-11-04
EP3380468B1 (en) 2020-05-20
CN108349951B (zh) 2020-11-13
US20170152244A1 (en) 2017-06-01
MX2018006374A (es) 2019-07-08
ES2806723T3 (es) 2021-02-18
RU2018122012A (ru) 2019-12-30
JP2018535226A (ja) 2018-11-29
CN108349951A (zh) 2018-07-31
TW201731837A (zh) 2017-09-16
AU2016360970B2 (en) 2019-11-07
US10196382B2 (en) 2019-02-05
AU2016360970A1 (en) 2018-07-05
WO2017089587A1 (en) 2017-06-01
DK3380468T3 (da) 2020-07-27
KR20180083426A (ko) 2018-07-20

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