IL245139B - Vaginal inserted estradiol pharmaceutical compositions and methods - Google Patents

Vaginal inserted estradiol pharmaceutical compositions and methods

Info

Publication number
IL245139B
IL245139B IL245139A IL24513916A IL245139B IL 245139 B IL245139 B IL 245139B IL 245139 A IL245139 A IL 245139A IL 24513916 A IL24513916 A IL 24513916A IL 245139 B IL245139 B IL 245139B
Authority
IL
Israel
Prior art keywords
methods
pharmaceutical compositions
vaginal
estradiol pharmaceutical
vaginal inserted
Prior art date
Application number
IL245139A
Other languages
Hebrew (he)
Other versions
IL245139A0 (en
Inventor
Brian A Bernick
Janice Louise Cacace
Peter H R Persicaner
Julia M Amadio
Thorsteinn Thorsteinsson
Frederick D Sancilio
Irani Neda
Original Assignee
Therapeuticsmd Inc
Brian A Bernick
Janice Louise Cacace
Peter H R Persicaner
Julia M Amadio
Thorsteinn Thorsteinsson
Frederick D Sancilio
Irani Neda
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US14/099,562 external-priority patent/US8987237B2/en
Priority claimed from PCT/US2014/061811 external-priority patent/WO2015073177A1/en
Application filed by Therapeuticsmd Inc, Brian A Bernick, Janice Louise Cacace, Peter H R Persicaner, Julia M Amadio, Thorsteinn Thorsteinsson, Frederick D Sancilio, Irani Neda filed Critical Therapeuticsmd Inc
Publication of IL245139A0 publication Critical patent/IL245139A0/en
Publication of IL245139B publication Critical patent/IL245139B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F6/00—Contraceptive devices; Pessaries; Applicators therefor
    • A61F6/06—Contraceptive devices; Pessaries; Applicators therefor for use by females
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A61K9/4825—Proteins, e.g. gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4875—Compounds of unknown constitution, e.g. material from plants or animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
IL245139A 2013-10-22 2016-04-14 Vaginal inserted estradiol pharmaceutical compositions and methods IL245139B (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201361894411P 2013-10-22 2013-10-22
US14/099,562 US8987237B2 (en) 2011-11-23 2013-12-06 Natural combination hormone replacement formulations and therapies
US201461932140P 2014-01-27 2014-01-27
PCT/US2014/061811 WO2015073177A1 (en) 2013-10-10 2014-10-22 Vaginal inserted estradiol pharmaceutical compositons and methods

Publications (2)

Publication Number Publication Date
IL245139A0 IL245139A0 (en) 2016-06-30
IL245139B true IL245139B (en) 2020-08-31

Family

ID=55697531

Family Applications (1)

Application Number Title Priority Date Filing Date
IL245139A IL245139B (en) 2013-10-22 2016-04-14 Vaginal inserted estradiol pharmaceutical compositions and methods

Country Status (8)

Country Link
EP (1) EP3060179A4 (en)
JP (1) JP6680672B2 (en)
KR (2) KR102335160B1 (en)
AU (3) AU2014349132A1 (en)
BR (1) BR112016009008B8 (en)
IL (1) IL245139B (en)
MX (1) MX2022002614A (en)
RU (1) RU2713888C2 (en)

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2739558B1 (en) * 1995-10-05 1997-11-28 Innothera Lab Sa UNITAL GALENIC FORM FOR LOCAL HORMONOTHERAPY OF VAGINAL DROUGHT
FR2759292B1 (en) * 1997-02-10 2000-08-11 Cird Galderma USE OF RETINOIDS AS PIGMENTATION INDUCING AGENTS
WO1999022680A1 (en) * 1997-11-03 1999-05-14 Deschutes Medical Products, Inc. Pessary with medicated cartridge
CA2293605A1 (en) * 1998-04-11 1999-10-21 Paolo Luca Maria Giorgetti Pharmaceutical preparations containing hydrosoluble ketoprofen salts and their application
WO2003039524A1 (en) * 2001-11-09 2003-05-15 Pharmacia Ab Anti-muscarinic agent and estrogen-agonist for treating unstable or overactive bladder
AU2003290071A1 (en) * 2002-12-18 2004-07-09 Ferrer Internacional, S.A. Pharmaceutical compositions of sertaconazole for vaginal use
US20060040904A1 (en) * 2004-08-17 2006-02-23 Ahmed Salah U Vaginal cream compositions, kits thereof and methods of using thereof
JP2009504667A (en) * 2005-08-12 2009-02-05 ドラッグテック コーポレイション Estrogen composition and method of treatment by use thereof
EP1872775A1 (en) * 2006-06-29 2008-01-02 Polichem S.A. Use of a hydrophilic matrix comprising a polyacrylic acid derivative, a cellulose ether and a disintegrant for the manufacture of a medicament for treating female genital disorders
WO2013112947A1 (en) * 2012-01-26 2013-08-01 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
CA2856520C (en) * 2011-11-23 2021-04-06 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
WO2013130535A1 (en) * 2012-02-27 2013-09-06 Newgen Biopharma Corporation Topical delivery of hormonal and non hormonal nano formulations, methods of making and using the same

Also Published As

Publication number Publication date
JP6680672B2 (en) 2020-04-15
KR20210148435A (en) 2021-12-07
JP2016534025A (en) 2016-11-04
KR102488424B1 (en) 2023-01-12
BR112016009008A2 (en) 2017-08-01
IL245139A0 (en) 2016-06-30
BR112016009008B8 (en) 2023-01-31
RU2016118396A3 (en) 2018-07-17
AU2014349132A1 (en) 2016-04-14
KR20160062097A (en) 2016-06-01
AU2014349132A8 (en) 2016-07-14
AU2019204658B2 (en) 2021-05-20
RU2016118396A (en) 2017-11-28
AU2019204658A1 (en) 2019-07-18
KR102335160B1 (en) 2021-12-03
RU2713888C2 (en) 2020-02-10
BR112016009008B1 (en) 2022-09-06
MX2022002614A (en) 2022-04-11
AU2021218231A1 (en) 2021-09-09
EP3060179A1 (en) 2016-08-31
EP3060179A4 (en) 2017-05-17

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed