IL227623B - Preparations of extremely tiny particles containing a population of particles, for use in creating a medicine for topical treatment in patients who suffer or tend to suffer from a disease related to the sweat glands and/or the mammary glands - Google Patents
Preparations of extremely tiny particles containing a population of particles, for use in creating a medicine for topical treatment in patients who suffer or tend to suffer from a disease related to the sweat glands and/or the mammary glandsInfo
- Publication number
- IL227623B IL227623B IL227623A IL22762313A IL227623B IL 227623 B IL227623 B IL 227623B IL 227623 A IL227623 A IL 227623A IL 22762313 A IL22762313 A IL 22762313A IL 227623 B IL227623 B IL 227623B
- Authority
- IL
- Israel
- Prior art keywords
- glands
- population
- susceptible
- treating
- particles
- Prior art date
Links
- 239000003814 drug Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 239000002105 nanoparticle Substances 0.000 title 1
- 239000002245 particle Substances 0.000 title 1
- 210000001732 sebaceous gland Anatomy 0.000 title 1
- 210000000106 sweat gland Anatomy 0.000 title 1
- 230000000699 topical effect Effects 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0241—Containing particulates characterized by their shape and/or structure
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
- A61K38/4893—Botulinum neurotoxin (3.4.24.69)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/66—Enzymes
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
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- A—HUMAN NECESSITIES
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
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- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
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- A—HUMAN NECESSITIES
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- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
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- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/12—Keratolytics, e.g. wart or anti-corn preparations
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
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- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P31/04—Antibacterial agents
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- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q15/00—Anti-perspirants or body deodorants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/41—Particular ingredients further characterized by their size
- A61K2800/413—Nanosized, i.e. having sizes below 100 nm
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/56—Compounds, absorbed onto or entrapped into a solid carrier, e.g. encapsulated perfumes, inclusion compounds, sustained release forms
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/24—Metalloendopeptidases (3.4.24)
- C12Y304/24069—Bontoxilysin (3.4.24.69), i.e. botulinum neurotoxin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Neurology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Birds (AREA)
- Molecular Biology (AREA)
- Pain & Pain Management (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Reproductive Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Endocrinology (AREA)
- Dispersion Chemistry (AREA)
- Physical Education & Sports Medicine (AREA)
- Genetics & Genomics (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Psychology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161435780P | 2011-01-24 | 2011-01-24 | |
| PCT/US2012/022276 WO2012103035A1 (en) | 2011-01-24 | 2012-01-23 | Nanoparticle compositions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL227623A0 IL227623A0 (en) | 2013-09-30 |
| IL227623B true IL227623B (en) | 2018-04-30 |
Family
ID=45563579
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL227623A IL227623B (en) | 2011-01-24 | 2013-07-24 | Preparations of extremely tiny particles containing a population of particles, for use in creating a medicine for topical treatment in patients who suffer or tend to suffer from a disease related to the sweat glands and/or the mammary glands |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US20120328702A1 (enExample) |
| EP (2) | EP2667854B1 (enExample) |
| JP (2) | JP5938838B2 (enExample) |
| KR (1) | KR20140003572A (enExample) |
| CN (3) | CN107714645A (enExample) |
| AU (2) | AU2012209339B2 (enExample) |
| BR (1) | BR112013018918A2 (enExample) |
| DK (1) | DK2667854T3 (enExample) |
| ES (1) | ES2720648T3 (enExample) |
| IL (1) | IL227623B (enExample) |
| SG (1) | SG193970A1 (enExample) |
| TR (1) | TR201905477T4 (enExample) |
| WO (1) | WO2012103035A1 (enExample) |
| ZA (1) | ZA201306391B (enExample) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9486408B2 (en) * | 2005-12-01 | 2016-11-08 | University Of Massachusetts Lowell | Botulinum nanoemulsions |
| EP2494958A1 (en) | 2006-12-01 | 2012-09-05 | Anterios, Inc. | Amphiphilic Entity Nanoparticles |
| CA2696570C (en) | 2007-08-17 | 2020-12-29 | Novartis Ag | Cyclic depsipeptides |
| AR086168A1 (es) | 2011-04-20 | 2013-11-27 | Novartis Ag | Procesos para la elaboracion de depsipeptidos macrociclicos e intermediarios |
| US8680054B2 (en) | 2011-04-20 | 2014-03-25 | Novartis Ag | Suspension type topical formulations comprising cyclic depsipeptide |
| US20140051637A1 (en) * | 2011-04-28 | 2014-02-20 | National University Corporation Nagoya University | Brain-targeting functional nucleic acid and use thereof |
| US9067978B2 (en) | 2012-10-09 | 2015-06-30 | Novartis Ag | Solution phase processes for the manufacture of macrocyclic depsipeptides and new intermediates |
| US8987413B2 (en) | 2012-10-09 | 2015-03-24 | Novartis Ag | Aldehyde acetal based processes for the manufacture of macrocyclic depsipeptides and new intermediates |
| EP3068422A1 (en) * | 2013-11-12 | 2016-09-21 | Colgate-Palmolive Company | Screening methods for antiperspirants |
| AU2015252947B2 (en) * | 2014-05-01 | 2020-07-09 | Anterios, Inc. | Demonstrable efficacy across or within patient populations |
| US10512658B2 (en) | 2015-09-16 | 2019-12-24 | Clutch, Inc. | Compositions for the treatment of sweating and methods for making same |
| US10149805B2 (en) | 2015-09-16 | 2018-12-11 | Clutch, Inc. | Compositions for the treatment of sweating and methods for making same |
| CN105249559A (zh) * | 2015-10-27 | 2016-01-20 | 浙江华尔纺织科技有限公司 | 一种美肤护跟套 |
| JP6873598B2 (ja) * | 2015-12-22 | 2021-05-19 | ロレアル | 活性成分のための改善された局所送達系 |
| KR101679992B1 (ko) * | 2015-12-31 | 2016-11-28 | 주식회사 유유제약 | 프로필렌글리콜 모노라우레이트를 포함하는 두타스테리드의 약학적 조성물 및 이의 제조 방법 |
| KR20190123256A (ko) * | 2016-07-29 | 2019-10-31 | 로저 엘. 카스파 | 액취증 치료 방법 |
| US11311496B2 (en) * | 2016-11-21 | 2022-04-26 | Eirion Therapeutics, Inc. | Transdermal delivery of large agents |
| FR3061434B1 (fr) * | 2017-01-04 | 2019-07-12 | Pierre Fabre Dermo-Cosmetique | Composition cosmetique comprenant une association d'huile de pongamia et de pentylene glycol 4-t-butylcyclohexanol pour lutter contre la rosacee |
| DK3431072T3 (da) | 2017-07-17 | 2020-02-17 | Dr August Wolff Gmbh & Co Kg Arzneimittel | Olie-i-vand-emulsion |
| US12280114B2 (en) * | 2018-03-29 | 2025-04-22 | Institute Of Basic Medical Sciences | Extraction of plant source “medicinal soup” and manual preparation of “herbal medicine” and related products |
| WO2020056191A1 (en) | 2018-09-13 | 2020-03-19 | Eirion Therapeutics, Inc. | Uses of plasminogen activator inhibitor 1 (pai-1) inhibitors |
| EP3849539A1 (en) | 2018-09-13 | 2021-07-21 | Eirion Therapeutics, Inc. | Plasminogen activator inhibitor 1 (pai-1) inhibitors and uses therefor |
| AU2019391791A1 (en) | 2018-12-03 | 2021-06-03 | Eirion Therapeutics, Inc. | Improved delivery of large agents |
| WO2020152350A1 (en) * | 2019-01-25 | 2020-07-30 | Nogra Pharma Limited | Compositions for use in preventing acne |
| WO2020185685A1 (en) * | 2019-03-08 | 2020-09-17 | The Regents Of The University Of California | Compositions and methods for treating acne |
| US20220273765A1 (en) * | 2019-04-24 | 2022-09-01 | Follicum Ab | Topical formulation |
| JP2022533113A (ja) | 2019-05-14 | 2022-07-21 | エイリオン セラピューティクス, インコーポレイテッド | ピーク効果の遅延および/または応答持続時間の延長 |
| US12280096B2 (en) | 2021-07-12 | 2025-04-22 | Penland Foundation | Treatments of cancer using nitrous oxide and botulinum toxin |
| JP2023527162A (ja) * | 2020-05-18 | 2023-06-27 | マックス バイオロジー カンパニー リミテッド | 脂質ポリマー組成物及び使用方法 |
| CN113081905B (zh) * | 2021-04-28 | 2022-11-18 | 媞颂日化用品(广州)有限公司 | 一种仿生皮脂膜组合物及其制备方法和应用 |
| US20240245611A1 (en) | 2021-05-25 | 2024-07-25 | Evonik Operations Gmbh | Hard-shell capsule with influx prevention of gastric fluids |
| EP4346779A1 (en) | 2021-05-25 | 2024-04-10 | Evonik Operations GmbH | Hard shell capsules with modified release coating |
| MX2024000408A (es) | 2021-07-09 | 2024-01-29 | Evonik Operations Gmbh | Capsulas de cubierta dura que tienen liberacion en el colon mejorada. |
| IL315022A (en) | 2022-02-22 | 2024-10-01 | Evonik Operations Gmbh | Hard shell capsule with at least one coating layer with low oxygen permeability |
| KR20240158254A (ko) | 2022-03-15 | 2024-11-04 | 에보닉 오퍼레이션스 게엠베하 | pH 값 5 내지 5.5 에서 약물 방출이 가속화되는 사전 기능화된 경질 쉘 캡슐 |
| WO2023214016A1 (en) | 2022-05-06 | 2023-11-09 | Evonik Operations Gmbh | Dosage form with drug release at ph 3 to 6 using double coating system with at least one release acceleration agent |
| CN115382476B (zh) * | 2022-07-26 | 2024-10-22 | 华东师范大学 | 一种超小粒径聚合物纳米颗粒的制备方法 |
| WO2024150216A1 (en) * | 2023-01-09 | 2024-07-18 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Topical compositions and methods for treating alopecia |
| WO2025064449A1 (en) | 2023-09-18 | 2025-03-27 | Eirion Therapeutics, Inc. | Topical compositions and uses of pai-1 inhibitors |
| WO2025092792A1 (zh) * | 2023-10-31 | 2025-05-08 | 妍诗美社(海南)医美健康科技有限公司 | 一种大分子透皮微乳系统及其应用 |
Family Cites Families (76)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US296006A (en) | 1884-04-01 | John hoefleb | ||
| US4270537A (en) | 1979-11-19 | 1981-06-02 | Romaine Richard A | Automatic hypodermic syringe |
| US4908154A (en) | 1981-04-17 | 1990-03-13 | Biotechnology Development Corporation | Method of forming a microemulsion |
| US4533254A (en) | 1981-04-17 | 1985-08-06 | Biotechnology Development Corporation | Apparatus for forming emulsions |
| US4596556A (en) | 1985-03-25 | 1986-06-24 | Bioject, Inc. | Hypodermic injection apparatus |
| AU98530S (en) | 1985-06-20 | 1987-11-05 | Novartis Ag | Subdivided membrane controlled transdermal device |
| US5116742A (en) | 1986-12-03 | 1992-05-26 | University Patents, Inc. | RNA ribozyme restriction endoribonucleases and methods |
| US4886499A (en) | 1986-12-18 | 1989-12-12 | Hoffmann-La Roche Inc. | Portable injection appliance |
| GB8704027D0 (en) | 1987-02-20 | 1987-03-25 | Owen Mumford Ltd | Syringe needle combination |
| US4790824A (en) | 1987-06-19 | 1988-12-13 | Bioject, Inc. | Non-invasive hypodermic injection device |
| US4941880A (en) | 1987-06-19 | 1990-07-17 | Bioject, Inc. | Pre-filled ampule and non-invasive hypodermic injection device assembly |
| US4940460A (en) | 1987-06-19 | 1990-07-10 | Bioject, Inc. | Patient-fillable and non-invasive hypodermic injection device assembly |
| US5339163A (en) | 1988-03-16 | 1994-08-16 | Canon Kabushiki Kaisha | Automatic exposure control device using plural image plane detection areas |
| FR2638359A1 (fr) | 1988-11-03 | 1990-05-04 | Tino Dalto | Guide de seringue avec reglage de la profondeur de penetration de l'aiguille dans la peau |
| US5008110A (en) | 1988-11-10 | 1991-04-16 | The Procter & Gamble Company | Storage-stable transdermal patch |
| US5064413A (en) | 1989-11-09 | 1991-11-12 | Bioject, Inc. | Needleless hypodermic injection device |
| US5312335A (en) | 1989-11-09 | 1994-05-17 | Bioject Inc. | Needleless hypodermic injection device |
| US6005087A (en) | 1995-06-06 | 1999-12-21 | Isis Pharmaceuticals, Inc. | 2'-modified oligonucleotides |
| US6399754B1 (en) | 1991-12-24 | 2002-06-04 | Isis Pharmaceuticals, Inc. | Sugar modified oligonucleotides |
| US5190521A (en) | 1990-08-22 | 1993-03-02 | Tecnol Medical Products, Inc. | Apparatus and method for raising a skin wheal and anesthetizing skin |
| US6165500A (en) | 1990-08-24 | 2000-12-26 | Idea Ag | Preparation for the application of agents in mini-droplets |
| JPH04198122A (ja) * | 1990-11-28 | 1992-07-17 | Procter & Gamble Co:The | チオールヘテロ環脱臭組成物及び脱臭方法 |
| JPH04198123A (ja) * | 1990-11-28 | 1992-07-17 | Procter & Gamble Co:The | アミン脱臭組成物及び脱臭方法 |
| JPH04202122A (ja) * | 1990-11-28 | 1992-07-22 | Procter & Gamble Co:The | ジケトン脱臭組成物及び脱臭方法 |
| US5527288A (en) | 1990-12-13 | 1996-06-18 | Elan Medical Technologies Limited | Intradermal drug delivery device and method for intradermal delivery of drugs |
| GB9118204D0 (en) | 1991-08-23 | 1991-10-09 | Weston Terence E | Needle-less injector |
| SE9102652D0 (sv) | 1991-09-13 | 1991-09-13 | Kabi Pharmacia Ab | Injection needle arrangement |
| US7384918B2 (en) | 1991-09-24 | 2008-06-10 | Allergan, Inc. | Botulinum toxin for treating muscle contracture |
| US6939852B2 (en) | 1991-09-24 | 2005-09-06 | Allergan, Inc. | Methods and compositions for the treatment of cerebral palsy |
| US5328483A (en) | 1992-02-27 | 1994-07-12 | Jacoby Richard M | Intradermal injection device with medication and needle guard |
| US6010715A (en) | 1992-04-01 | 2000-01-04 | Bertek, Inc. | Transdermal patch incorporating a polymer film incorporated with an active agent |
| US5383851A (en) | 1992-07-24 | 1995-01-24 | Bioject Inc. | Needleless hypodermic injection device |
| US5569189A (en) | 1992-09-28 | 1996-10-29 | Equidyne Systems, Inc. | hypodermic jet injector |
| US5334144A (en) | 1992-10-30 | 1994-08-02 | Becton, Dickinson And Company | Single use disposable needleless injector |
| US5591767A (en) | 1993-01-25 | 1997-01-07 | Pharmetrix Corporation | Liquid reservoir transdermal patch for the administration of ketorolac |
| IT1261849B (it) | 1993-09-02 | 1996-06-03 | Avantgarde Spa | Dispositivo medico per la somministrazione di principi attivi o farmaci a bassissimo dosaggio, in particolare di farmaci omeopatici. |
| US5798340A (en) | 1993-09-17 | 1998-08-25 | Gilead Sciences, Inc. | Nucleotide analogs |
| WO1995024176A1 (en) | 1994-03-07 | 1995-09-14 | Bioject, Inc. | Ampule filling device |
| US5466220A (en) | 1994-03-08 | 1995-11-14 | Bioject, Inc. | Drug vial mixing and transfer device |
| US5596091A (en) | 1994-03-18 | 1997-01-21 | The Regents Of The University Of California | Antisense oligonucleotides comprising 5-aminoalkyl pyrimidine nucleotides |
| US5599302A (en) | 1995-01-09 | 1997-02-04 | Medi-Ject Corporation | Medical injection system and method, gas spring thereof and launching device using gas spring |
| US5730723A (en) | 1995-10-10 | 1998-03-24 | Visionary Medical Products Corporation, Inc. | Gas pressured needle-less injection device and method |
| US5893397A (en) | 1996-01-12 | 1999-04-13 | Bioject Inc. | Medication vial/syringe liquid-transfer apparatus |
| GB9607549D0 (en) | 1996-04-11 | 1996-06-12 | Weston Medical Ltd | Spring-powered dispensing device |
| US5922695A (en) | 1996-07-26 | 1999-07-13 | Gilead Sciences, Inc. | Antiviral phosphonomethyoxy nucleotide analogs having increased oral bioavarilability |
| US6127533A (en) | 1997-02-14 | 2000-10-03 | Isis Pharmaceuticals, Inc. | 2'-O-aminooxy-modified oligonucleotides |
| US5993412A (en) | 1997-05-19 | 1999-11-30 | Bioject, Inc. | Injection apparatus |
| US5948433A (en) | 1997-08-21 | 1999-09-07 | Bertek, Inc. | Transdermal patch |
| IT1298087B1 (it) | 1998-01-08 | 1999-12-20 | Fiderm S R L | Dispositivo per il controllo della profondita' di penetrazione di un ago, in particolare applicabile ad una siringa per iniezioni |
| US5965154A (en) | 1998-03-17 | 1999-10-12 | Plc Holding, L.L.C. | Adhesive matrix type transdermal patch and method of manufacturing same |
| US6403779B1 (en) | 1999-01-08 | 2002-06-11 | Isis Pharmaceuticals, Inc. | Regioselective synthesis of 2′-O-modified nucleosides |
| US7780967B2 (en) * | 2000-02-08 | 2010-08-24 | Allergan, Inc. | Reduced toxicity Clostridial toxin pharmaceutical compositions |
| US8202979B2 (en) | 2002-02-20 | 2012-06-19 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid |
| US20050032733A1 (en) | 2001-05-18 | 2005-02-10 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (SiNA) |
| US20050020525A1 (en) | 2002-02-20 | 2005-01-27 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA) |
| US20030072841A1 (en) * | 2001-03-19 | 2003-04-17 | The Procter & Gamble Campany | Polybutene containing chewing gum and confection |
| US20030175950A1 (en) | 2001-05-29 | 2003-09-18 | Mcswiggen James A. | RNA interference mediated inhibition of HIV gene expression using short interfering RNA |
| EP2390328A1 (en) | 2001-09-28 | 2011-11-30 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | MicroRNA molecules |
| US7763663B2 (en) | 2001-12-19 | 2010-07-27 | University Of Massachusetts | Polysaccharide-containing block copolymer particles and uses thereof |
| WO2003105780A2 (en) | 2002-06-18 | 2003-12-24 | Epigenesis Pharmaceuticals, Inc. | A dry powder oligonucleotide formulation, preparation and its uses |
| US20040009180A1 (en) | 2002-07-11 | 2004-01-15 | Allergan, Inc. | Transdermal botulinum toxin compositions |
| US7824693B2 (en) * | 2002-08-19 | 2010-11-02 | Ira Sanders | Treatment of fine wrinkles with clostridia neurotoxins |
| PT1729821E (pt) * | 2004-03-03 | 2013-10-23 | Revance Therapeutics Inc | Composições e métodos para aplicação tópica e administração transdérmica de toxinas botulínicas |
| CN103315954A (zh) | 2005-07-18 | 2013-09-25 | 麻萨诸塞州洛厄尔大学 | 制备与使用纳米乳剂的组合物和方法 |
| TR201901443T4 (tr) * | 2005-12-01 | 2019-02-21 | Univ Massachusetts Lowell | Botulinum nanoemülsiyonları. |
| US20080206155A1 (en) * | 2006-11-14 | 2008-08-28 | Foamix Ltd. | Stable non-alcoholic foamable pharmaceutical emulsion compositions with an unctuous emollient and their uses |
| CA2671133C (en) | 2006-12-01 | 2015-11-24 | Anterios, Inc. | Peptide nanoparticles and uses therefor |
| EP2494958A1 (en) * | 2006-12-01 | 2012-09-05 | Anterios, Inc. | Amphiphilic Entity Nanoparticles |
| EP1938801A1 (en) * | 2006-12-22 | 2008-07-02 | Biofrontera Bioscience GmbH | Nanoemulsion |
| US10016451B2 (en) * | 2007-05-31 | 2018-07-10 | Anterios, Inc. | Nucleic acid nanoparticles and uses therefor |
| US9511016B2 (en) * | 2007-06-12 | 2016-12-06 | Epicentrx, Inc. | Topical composition for treating pain |
| BRPI0817664A2 (pt) * | 2007-10-12 | 2015-03-24 | Massachusetts Inst Technology | Nanopartículas, método para preparar nanopartículas e método para tratar terapeuticamente ou profilaticamente um indivíduo |
| KR20160130519A (ko) * | 2008-06-26 | 2016-11-11 | 안테리오스, 인코퍼레이티드 | 경피 운반 |
| EP2667860A1 (en) * | 2011-01-24 | 2013-12-04 | Anterios, Inc. | Compositions of empty nanoparticles and their use for treating dermatological conditions |
| WO2012103038A2 (en) * | 2011-01-24 | 2012-08-02 | Anterios, Inc. | Nanoparticle compositions, formulations thereof, and uses therefor |
| US20120328549A1 (en) * | 2011-01-24 | 2012-12-27 | Anterios, Inc. | Oil compositions |
-
2012
- 2012-01-23 WO PCT/US2012/022276 patent/WO2012103035A1/en not_active Ceased
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| EP2667854B1 (en) | 2019-01-16 |
| KR20140003572A (ko) | 2014-01-09 |
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| AU2017202420A1 (en) | 2017-04-27 |
| ZA201306391B (en) | 2014-04-30 |
| ES2720648T3 (es) | 2019-07-23 |
| JP2014528900A (ja) | 2014-10-30 |
| WO2012103035A1 (en) | 2012-08-02 |
| AU2012209339B2 (en) | 2017-05-11 |
| TR201905477T4 (tr) | 2019-05-21 |
| IL227623A0 (en) | 2013-09-30 |
| JP5938838B2 (ja) | 2016-06-22 |
| EP2667854A1 (en) | 2013-12-04 |
| DK2667854T3 (en) | 2019-04-23 |
| US20150196490A1 (en) | 2015-07-16 |
| CN103747782A (zh) | 2014-04-23 |
| AU2012209339A1 (en) | 2013-09-12 |
| BR112013018918A2 (pt) | 2016-10-04 |
| SG193970A1 (en) | 2013-11-29 |
| US20120328702A1 (en) | 2012-12-27 |
| CN109464393A (zh) | 2019-03-15 |
| JP2016121175A (ja) | 2016-07-07 |
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