IL213589A0 - DIPYRIDO [2,3-d;4-d] PYRROL DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM - Google Patents

DIPYRIDO [2,3-d;4-d] PYRROL DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Info

Publication number
IL213589A0
IL213589A0 IL213589A IL21358911A IL213589A0 IL 213589 A0 IL213589 A0 IL 213589A0 IL 213589 A IL213589 A IL 213589A IL 21358911 A IL21358911 A IL 21358911A IL 213589 A0 IL213589 A0 IL 213589A0
Authority
IL
Israel
Prior art keywords
dipyrido
preparation
pharmaceutical compositions
compositions containing
pyrrol derivatives
Prior art date
Application number
IL213589A
Other versions
IL213589A (en
Original Assignee
Brugger Nadia
Jones Christopher Charles Victor
Merck Patents Gmbh
Sutton E Amanda
Askew Jr Benny C
Huck Bayard R
Smith Garry R
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Brugger Nadia, Jones Christopher Charles Victor, Merck Patents Gmbh, Sutton E Amanda, Askew Jr Benny C, Huck Bayard R, Smith Garry R filed Critical Brugger Nadia
Publication of IL213589A0 publication Critical patent/IL213589A0/en
Publication of IL213589A publication Critical patent/IL213589A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL213589A 2008-12-18 2011-06-16 Dipyrido [2,3-d;4-d] pyrrol derivatives, their preparation and pharmaceutical compositions containing them IL213589A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20302208P 2008-12-18 2008-12-18
PCT/US2009/066534 WO2010080253A1 (en) 2008-12-18 2009-12-03 Tricyclic azaindoles

Publications (2)

Publication Number Publication Date
IL213589A0 true IL213589A0 (en) 2011-07-31
IL213589A IL213589A (en) 2016-02-29

Family

ID=41682740

Family Applications (1)

Application Number Title Priority Date Filing Date
IL213589A IL213589A (en) 2008-12-18 2011-06-16 Dipyrido [2,3-d;4-d] pyrrol derivatives, their preparation and pharmaceutical compositions containing them

Country Status (8)

Country Link
US (1) US8853391B2 (en)
EP (1) EP2367822B1 (en)
JP (2) JP2012512871A (en)
AU (1) AU2009336040B2 (en)
CA (1) CA2745085C (en)
ES (1) ES2603208T3 (en)
IL (1) IL213589A (en)
WO (1) WO2010080253A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2558446T5 (en) 2010-04-16 2019-12-09 Ac Immune Sa New compounds for the treatment of diseases associated with amyloid or amyloid-like proteins
KR20150130398A (en) * 2013-03-14 2015-11-23 브리스톨-마이어스 스큅 컴퍼니 Bicyclo [2.2.2] acid gpr120 modulators
GB201704325D0 (en) * 2017-03-17 2017-05-03 Argonaut Therapeutics Ltd Compounds
CN111757882B (en) * 2018-01-05 2023-08-22 Ac免疫有限公司 Compounds for treating, alleviating or preventing conditions associated with tau aggregates
US10633383B2 (en) 2018-01-05 2020-04-28 Ac Immune Sa Compounds for the treatment, alleviation or prevention of disorders associated with Tau aggregates
EA202091395A1 (en) * 2018-06-04 2020-10-01 Ас Иммьюн Са DERIVATIVES OF 1,3,4,5-TETRAHYDRO-2H-PYRIDO [4,3-b] INDOL FOR TREATMENT, RELIEF OR PREVENTION OF DISORDERS ASSOCIATED WITH TAU AGGREGATES SUCH AS ALZHEIMER'S DISEASE
CN112313230B (en) * 2018-06-04 2024-03-15 Ac免疫有限公司 Novel compounds for the treatment, alleviation or prevention of conditions associated with Tau aggregate
WO2020037155A1 (en) * 2018-08-16 2020-02-20 Recreo Pharmaceuticals Llc 1,3,4,9-tetrahydro-2h-pyrido[3,4-b]indole derivative compounds and uses thereof
CA3131805C (en) 2019-03-01 2023-11-21 Ac Immune Sa Novel compounds for the treatment, alleviation or prevention of disorders associated with tau aggregates

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1268771A (en) * 1968-03-15 1972-03-29 Glaxo Lab Ltd Azacarbazoles
GB9624482D0 (en) 1995-12-18 1997-01-15 Zeneca Phaema S A Chemical compounds
EP0880508B1 (en) 1996-02-13 2003-04-16 AstraZeneca AB Quinazoline derivatives as vegf inhibitors
ATE211134T1 (en) 1996-03-05 2002-01-15 4-ANILINOQUINAZOLINE DERIVATIVES
GB9718972D0 (en) 1996-09-25 1997-11-12 Zeneca Ltd Chemical compounds
GB9714249D0 (en) 1997-07-08 1997-09-10 Angiogene Pharm Ltd Vascular damaging agents
US6589954B1 (en) * 1998-05-22 2003-07-08 Scios, Inc. Compounds and methods to treat cardiac failure and other disorders
GB9900334D0 (en) 1999-01-07 1999-02-24 Angiogene Pharm Ltd Tricylic vascular damaging agents
GB9900752D0 (en) 1999-01-15 1999-03-03 Angiogene Pharm Ltd Benzimidazole vascular damaging agents
KR20030013433A (en) 2000-05-31 2003-02-14 아스트라제네카 아베 Indole derivatives with vascular damaging activity
AU6623301A (en) 2000-07-07 2002-01-21 Angiogene Pharm Ltd Colchinol derivatives as vascular damaging agents
EE200300015A (en) 2000-07-07 2004-10-15 Angiogene Pharmaceuticals Limited Colchinol derivatives as inhibitors of angiogenesis
US20040014676A1 (en) * 2001-07-09 2004-01-22 Ramalinga Dharanipragada SRC kinase inhibitors useful for treating osteoporosis
FR2891459B1 (en) * 2005-09-30 2007-12-28 Flamel Technologies Sa MICROPARTICLES WITH MODIFIED RELEASE OF AT LEAST ONE ACTIVE INGREDIENT AND ORAL GALENIC FORM COMPRISING THE SAME
US8119655B2 (en) * 2005-10-07 2012-02-21 Takeda Pharmaceutical Company Limited Kinase inhibitors
EP2049535A1 (en) * 2006-08-02 2009-04-22 Takeda Pharmaceutical Company Limited Alpha-carboline derivatives and methods for preparation thereof
AU2008269513B2 (en) * 2007-06-26 2011-06-16 Astrazeneca Ab 1-cyanocyclopropyl-derivatives as cathepsin K inhibitors
RU2007139634A (en) * 2007-10-25 2009-04-27 Сергей Олегович Бачурин (RU) NEW THIAZOLE-, TRIAZOLE- OR OXADIAZOLE-CONTAINING TETRACYCLIC COMPOUNDS

Also Published As

Publication number Publication date
CA2745085A1 (en) 2010-07-15
JP2012512871A (en) 2012-06-07
AU2009336040A1 (en) 2011-06-30
US8853391B2 (en) 2014-10-07
AU2009336040B2 (en) 2015-07-16
JP6109880B2 (en) 2017-04-05
JP2015187155A (en) 2015-10-29
US20120022060A1 (en) 2012-01-26
CA2745085C (en) 2018-03-06
IL213589A (en) 2016-02-29
EP2367822A1 (en) 2011-09-28
WO2010080253A1 (en) 2010-07-15
ES2603208T3 (en) 2017-02-24
EP2367822B1 (en) 2016-10-05

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Legal Events

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KB Patent renewed
KB Patent renewed