IL209836A0 - Carboxylic acid salts of 2-amino-3-carbethoxyamino-6-(4-fluoro-benzylamino)-pyridine - Google Patents

Carboxylic acid salts of 2-amino-3-carbethoxyamino-6-(4-fluoro-benzylamino)-pyridine

Info

Publication number
IL209836A0
IL209836A0 IL209836A IL20983610A IL209836A0 IL 209836 A0 IL209836 A0 IL 209836A0 IL 209836 A IL209836 A IL 209836A IL 20983610 A IL20983610 A IL 20983610A IL 209836 A0 IL209836 A0 IL 209836A0
Authority
IL
Israel
Prior art keywords
carbethoxyamino
benzylamino
fluoro
pyridine
amino
Prior art date
Application number
IL209836A
Other versions
IL209836A (en
Original Assignee
Awd Pharma Gmbh & Co Kg
Hoock Christoph
Qadan Asal
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Awd Pharma Gmbh & Co Kg, Hoock Christoph, Qadan Asal filed Critical Awd Pharma Gmbh & Co Kg
Publication of IL209836A0 publication Critical patent/IL209836A0/en
Publication of IL209836A publication Critical patent/IL209836A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
IL209836A 2008-06-09 2010-12-08 Carboxylic acid salts of 2-amino-3-carbethoxyamino-6-(4-fluoro-benzylamino)-pyridine IL209836A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08010472 2008-06-09
PCT/US2009/046775 WO2009152168A2 (en) 2008-06-09 2009-06-09 Carboxylic acid salts of 2-amino-3-carbethoxyamino-6-(4-fluoro-benzylamino)-pyridine

Publications (2)

Publication Number Publication Date
IL209836A0 true IL209836A0 (en) 2011-02-28
IL209836A IL209836A (en) 2015-02-26

Family

ID=39939397

Family Applications (1)

Application Number Title Priority Date Filing Date
IL209836A IL209836A (en) 2008-06-09 2010-12-08 Carboxylic acid salts of 2-amino-3-carbethoxyamino-6-(4-fluoro-benzylamino)-pyridine

Country Status (5)

Country Link
US (1) US8183267B2 (en)
EP (1) EP2346826A2 (en)
EA (1) EA020545B1 (en)
IL (1) IL209836A (en)
WO (1) WO2009152168A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8183267B2 (en) * 2008-06-09 2012-05-22 Awd. Pharma Gmbh & Co. Kg Carboxylic acid salts of 2-amino-3-carbethoxyamino-6-(4-fluoro-benzylamino)-pyridine
US20120028930A1 (en) * 2010-02-26 2012-02-02 Bionevia Pharmaceuticals Inc. Flupirtine salts and polymorphs
AR081626A1 (en) 2010-04-23 2012-10-10 Cytokinetics Inc AMINO-PYRIDAZINIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM AND USE OF THE SAME TO TREAT CARDIAC AND SKELETIC MUSCULAR DISORDERS
US9133123B2 (en) 2010-04-23 2015-09-15 Cytokinetics, Inc. Certain amino-pyridines and amino-triazines, compositions thereof, and methods for their use
AR081331A1 (en) 2010-04-23 2012-08-08 Cytokinetics Inc AMINO- PYRIMIDINES COMPOSITIONS OF THE SAME AND METHODS FOR THE USE OF THE SAME
DE102010063612A1 (en) * 2010-12-20 2012-06-21 Awd.Pharma Gmbh & Co. Kg New multicomponent crystals of [2- [2-amino-6- (4-fluoro-benzylamino) -pyridin-3-yl] -carbamic acid ethyl ester and 2- [2 - [(2,6-dichlorophenyl) -amino] -phenyl] -acetic acid
DE102010063609A1 (en) * 2010-12-20 2012-06-21 Awd.Pharma Gmbh & Co. Kg New multicomponent crystals of ([2-amino-6- (4-fluoro-benzylamino) -pyridin-3yl) -carbamic acid ethyl ester and an arylpropionic acid

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1795858C2 (en) 1968-07-19 1979-01-11 Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler, 6000 Frankfurt Benzylaminopyridines
DE3133519A1 (en) 1980-09-13 1982-06-09 Degussa Ag, 6000 Frankfurt 2-Amino-3-carbethoxyamino-6-(p-fluorobenzylamino)pyridine maleate
DE3337593A1 (en) 1982-10-27 1984-05-03 Degussa Ag, 6000 Frankfurt 2-Amino-3-acylamino-6-benzylaminopyridine derivatives having antiepileptic action
DE3416609A1 (en) 1984-05-05 1985-11-07 Degussa Ag, 6000 Frankfurt 2-AMINO-3-ETHOXYCARBONYLAMINO-6- (P-FLUOR-BENZYLAMINO) - PYRIDINE GLUCONATE AND PHARMACEUTICAL PREPARATIONS THAT CONTAIN THIS SUBSTANCE
DE3915184A1 (en) 1988-05-16 1989-11-30 Asta Pharma Ag Substituted 3-(N-heterocyclyl)-2,6-diaminopyridines and -N-oxides, preparation thereof and use thereof as drugs
DE4319649A1 (en) 1993-03-18 1994-09-22 Asta Medica Ag Oral dosage forms containing flupirtine with controlled release of active ingredients
DE19716984A1 (en) 1997-04-23 1998-10-29 Asta Medica Ag Process for the preparation of pure flupirtine maleate and its modification A
DE19903275A1 (en) * 1999-01-28 2000-08-03 Merck Patent Gmbh Lyophilisates with improved reconstitutability
DE10327674A1 (en) * 2003-06-20 2005-01-05 Awd.Pharma Gmbh & Co. Kg Injectable dosage form of flupirtine
DE102005054610B4 (en) 2005-11-08 2010-06-10 Awd.Pharma Gmbh & Co. Kg Controlled-release drug preparation containing flupirtine
US8183267B2 (en) * 2008-06-09 2012-05-22 Awd. Pharma Gmbh & Co. Kg Carboxylic acid salts of 2-amino-3-carbethoxyamino-6-(4-fluoro-benzylamino)-pyridine

Also Published As

Publication number Publication date
EP2346826A2 (en) 2011-07-27
IL209836A (en) 2015-02-26
EA020545B1 (en) 2014-12-30
EA201071425A1 (en) 2011-06-30
US20090306150A1 (en) 2009-12-10
WO2009152168A2 (en) 2009-12-17
US8183267B2 (en) 2012-05-22
WO2009152168A3 (en) 2010-03-18

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