IL207247A0 - Use of ranolazine for the treatment of cardiovascular disease - Google Patents

Use of ranolazine for the treatment of cardiovascular disease

Info

Publication number
IL207247A0
IL207247A0 IL207247A IL20724710A IL207247A0 IL 207247 A0 IL207247 A0 IL 207247A0 IL 207247 A IL207247 A IL 207247A IL 20724710 A IL20724710 A IL 20724710A IL 207247 A0 IL207247 A0 IL 207247A0
Authority
IL
Israel
Prior art keywords
ranolazine
treatment
cardiovascular disease
cardiovascular
disease
Prior art date
Application number
IL207247A
Original Assignee
Gilead Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gilead Sciences Inc filed Critical Gilead Sciences Inc
Publication of IL207247A0 publication Critical patent/IL207247A0/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
IL207247A 2008-02-13 2010-07-27 Use of ranolazine for the treatment of cardiovascular disease IL207247A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12/030,468 US20090111826A1 (en) 2007-02-13 2008-02-13 Use of ranolazine for the treatment of cardiovascular diseases
PCT/US2009/033950 WO2009102886A1 (en) 2008-02-13 2009-02-12 Use of ranolazine for the treatment of cardiovascular diseases

Publications (1)

Publication Number Publication Date
IL207247A0 true IL207247A0 (en) 2010-12-30

Family

ID=40626660

Family Applications (1)

Application Number Title Priority Date Filing Date
IL207247A IL207247A0 (en) 2008-02-13 2010-07-27 Use of ranolazine for the treatment of cardiovascular disease

Country Status (13)

Country Link
US (2) US20090111826A1 (en)
EP (1) EP2252295A1 (en)
JP (1) JP2011511844A (en)
KR (1) KR20110013352A (en)
AU (1) AU2009214639A1 (en)
BR (1) BRPI0907956A2 (en)
CA (1) CA2714301A1 (en)
CO (1) CO6531499A2 (en)
EA (1) EA201070918A1 (en)
EC (1) ECSP10010464A (en)
IL (1) IL207247A0 (en)
MX (1) MX2010008433A (en)
WO (1) WO2009102886A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8822473B2 (en) * 2002-05-21 2014-09-02 Gilead Sciences, Inc. Method of treating diabetes
CN100551370C (en) 2002-05-21 2009-10-21 Cv医药有限公司 The application of ranolazine in the pharmaceutical composition of preparation treatment diabetes
US20080299195A1 (en) * 2007-05-31 2008-12-04 Brent Blackburn Use of ranolazine for elevated brain-type natriuretic peptide
EP2337559A2 (en) * 2008-09-04 2011-06-29 Gilead Sciences, Inc. Method of treating atrial fibrillation
AU2010248948A1 (en) * 2009-05-14 2011-12-01 Gilead Sciences, Inc. Ranolazine for the treatment of CNS disorders
MX2014000095A (en) * 2011-07-07 2014-05-28 Janssen Diagnostics Llc Method of analyzing cardiovascular disorders and uses thereof.

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US4567264A (en) * 1983-05-18 1986-01-28 Syntex (U.S.A.) Inc. Cardioselective aryloxy- and arylthio- hydroxypropylene-piperazinyl acetanilides which affect calcium entry
AU633589B2 (en) * 1989-06-23 1993-02-04 Syntex (U.S.A.) Inc. Novel methods of treatment using ranolazine and related piperazine derivatives
US5455045A (en) * 1993-05-13 1995-10-03 Syntex (U.S.A.) Inc. High dose formulations
US20030077229A1 (en) * 1997-10-01 2003-04-24 Dugger Harry A. Buccal, polar and non-polar spray or capsule containing cardiovascular or renal drugs
US6541479B1 (en) * 1997-12-02 2003-04-01 Massachusetts College Of Pharmacy Calcium channel blockers
US6897305B2 (en) * 1998-06-08 2005-05-24 Theravance, Inc. Calcium channel drugs and uses
US6479496B1 (en) * 1998-09-10 2002-11-12 Cv Therapeutics, Inc. Methods for treating angina with ranolazine
US6303607B1 (en) * 1998-09-10 2001-10-16 Cv Therapeutics, Inc. Method for administering a sustained release ranolanolazine formulation
US20050245502A1 (en) * 1999-08-23 2005-11-03 Phoenix Biosciences Treatments for viral infections
US6734192B1 (en) * 1999-08-23 2004-05-11 Mp-1 Inc. Treatment of viral infections
US6803457B1 (en) * 1999-09-30 2004-10-12 Pfizer, Inc. Compounds for the treatment of ischemia
IL151014A0 (en) * 2000-02-18 2003-02-12 Cv Therapeutics Inc Partial fatty acid oxidation inhibitors in the treatment of congestive heart failure
US20030220312A1 (en) * 2000-05-11 2003-11-27 G.D. Searle & Co. Epoxy-steroidal aldosterone antagonist and calcium channel blocker combination therapy for treatment of cardiovascular disorders
AU2001277938A1 (en) * 2000-07-21 2002-02-05 Cv Therapeutics, Inc. Method for treating angina
ES2281431T3 (en) * 2000-07-27 2007-10-01 Pharmacia Corporation COMBINATION THERAPY WITH AN ALGOSTERONE EPOXY-STEROID ANTAGONIST AND BALLOCK OF CALCIUM CHANNELS FOR TREATMENT OF CONGESTIVE CARDIAC INSUFFICIENCY.
GB0028414D0 (en) * 2000-11-22 2001-01-03 Univ Leeds Flush preservation solution
US6423705B1 (en) * 2001-01-25 2002-07-23 Pfizer Inc. Combination therapy
IL147696A0 (en) * 2001-01-25 2002-08-14 Pfizer Prod Inc Combination therapy
CZ20032031A3 (en) * 2001-01-26 2003-12-17 Schering Corporation Pharmaceutical preparation
US20030220310A1 (en) * 2001-07-27 2003-11-27 Schuh Joseph R. Epoxy-steroidal aldosterone antagonist and calcium channel blocker combination therapy for treatment of congestive heart failure
US20050250676A1 (en) * 2001-11-19 2005-11-10 Aventis Pharma Deutschland Gmbh Method of activating insulin receptor substrate-2 to stimulate insulin production
US6958352B2 (en) * 2002-02-08 2005-10-25 Smithkline Beecham Corporation Compounds for inhibiting insulin secretion and methods related thereto
IL163535A0 (en) * 2002-02-15 2005-12-18 Cv Therapeutics Inc Polymer coating for medical devices
US20030220344A1 (en) * 2002-04-04 2003-11-27 Luiz Belardinelli Method of treating arrhythmias
CN100551370C (en) * 2002-05-21 2009-10-21 Cv医药有限公司 The application of ranolazine in the pharmaceutical composition of preparation treatment diabetes
DE602004006388T2 (en) * 2003-03-05 2008-01-10 Metabolex, Inc., Hayward METHOD AND COMPOSITIONS FOR THE DIAGNOSIS AND TREATMENT OF DIABETES AND ASSOCIATED ILLNESSES WITH BETA-TRP (MTR1 / LTRPC5 / TRPM5)
EP2377528B1 (en) * 2003-06-12 2014-02-19 The Board of Regents of the University of Colorado Fatty acid metabolism inhibitors for use in the treatment of cancer
US20050074425A1 (en) * 2003-07-02 2005-04-07 Polycord, Inc. Method for delivering polymerized therapeutic agent compositions and compositions thereof
US7060723B2 (en) * 2003-08-29 2006-06-13 Allergan, Inc. Treating neurological disorders using selective antagonists of persistent sodium current
ES2258365B1 (en) * 2003-10-03 2007-12-01 Lacer, S.A. DERIVATIVES OF DISULFIDE, SULFIDE, SULFOXIDE AND SULFONE OF CYCLING SUGARS AND THEIR USES.
WO2005070126A2 (en) * 2004-01-08 2005-08-04 The Regents Of The University Of Colorado Methods and compositions for treating human diseases and wounds with ucp and fas inhibitors
US8829051B2 (en) * 2004-05-24 2014-09-09 Geoffrey C. GURTNER Method of treating or preventing pathologic effects of acute increases in hyperglycemia and/or acute increases of free fatty acid flux
EP1809289A1 (en) * 2004-11-09 2007-07-25 Cv Therapeutics, Inc. Use ranolazine in combination with at least one remodeling agent for reversing left ventricular remodeling in the treatment of heart failure
CN101098682A (en) * 2005-01-06 2008-01-02 Cv医药有限公司 Sustained release pharmaceutical formulations comprising ranolazine
AU2006223212A1 (en) * 2005-03-11 2006-09-21 Hong Kong Nitric Oxide Limited Combination therapy for endothelial dysfunction, angina and diabetes
JP2010514696A (en) * 2006-12-21 2010-05-06 ギリアード・パロ・アルト・インコーポレイテッド Reduction of cardiovascular symptoms
CA2677931A1 (en) * 2007-02-13 2008-08-21 Cv Therapeutics, Inc. Use of ranolazine for the treatment of cardiovascular diseases
CA2678319A1 (en) * 2007-02-13 2008-08-21 Cv Therapeutics, Inc. Use of ranolazine for the treatment of coronary microvascular diseases
CA2678325A1 (en) * 2007-02-13 2008-08-21 Cv Therapeutics, Inc. Use of ranolazine for the treatment of non-coronary microvascular diseases
WO2008116083A1 (en) * 2007-03-22 2008-09-25 Cv Therapeutics, Inc. Use of ranolazine for elevated brain-type natriuretic peptide
CN101678017A (en) * 2007-05-31 2010-03-24 Cv医药有限公司 Method of treating diabetes
US20080299195A1 (en) * 2007-05-31 2008-12-04 Brent Blackburn Use of ranolazine for elevated brain-type natriuretic peptide

Also Published As

Publication number Publication date
WO2009102886A1 (en) 2009-08-20
MX2010008433A (en) 2011-03-02
JP2011511844A (en) 2011-04-14
US20090111826A1 (en) 2009-04-30
AU2009214639A1 (en) 2009-08-20
BRPI0907956A2 (en) 2015-08-04
CA2714301A1 (en) 2009-08-20
EA201070918A1 (en) 2011-02-28
KR20110013352A (en) 2011-02-09
ECSP10010464A (en) 2010-10-30
US20100035890A1 (en) 2010-02-11
CO6531499A2 (en) 2012-09-28
EP2252295A1 (en) 2010-11-24

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