IL205153A0 - Compositions for treating parkinson's disease - Google Patents

Compositions for treating parkinson's disease

Info

Publication number
IL205153A0
IL205153A0 IL205153A IL20515310A IL205153A0 IL 205153 A0 IL205153 A0 IL 205153A0 IL 205153 A IL205153 A IL 205153A IL 20515310 A IL20515310 A IL 20515310A IL 205153 A0 IL205153 A0 IL 205153A0
Authority
IL
Israel
Prior art keywords
disease
compositions
treating parkinson
parkinson
treating
Prior art date
Application number
IL205153A
Other versions
IL205153A (en
Original Assignee
Vectura Group Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vectura Group Plc filed Critical Vectura Group Plc
Publication of IL205153A0 publication Critical patent/IL205153A0/en
Publication of IL205153A publication Critical patent/IL205153A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
IL205153A 2007-10-31 2010-04-15 Dry powder compostions comprising apomorphine and magnesium stearate for treating parkinson's disease IL205153A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0721394.5A GB0721394D0 (en) 2007-10-31 2007-10-31 Compositions for trating parkinson's disease
PCT/GB2008/003698 WO2009056851A1 (en) 2007-10-31 2008-10-31 Compositions for treating parkinson's disease

Publications (2)

Publication Number Publication Date
IL205153A0 true IL205153A0 (en) 2010-11-30
IL205153A IL205153A (en) 2014-11-30

Family

ID=38834618

Family Applications (1)

Application Number Title Priority Date Filing Date
IL205153A IL205153A (en) 2007-10-31 2010-04-15 Dry powder compostions comprising apomorphine and magnesium stearate for treating parkinson's disease

Country Status (16)

Country Link
US (1) US20100288276A1 (en)
EP (1) EP2214649A1 (en)
JP (1) JP2011500869A (en)
KR (1) KR20100091970A (en)
CN (1) CN101932307A (en)
AU (1) AU2008320569B2 (en)
BR (1) BRPI0818799A2 (en)
CA (1) CA2703063A1 (en)
GB (1) GB0721394D0 (en)
IL (1) IL205153A (en)
MX (1) MX2010004614A (en)
NZ (1) NZ584622A (en)
RU (1) RU2484823C2 (en)
SG (1) SG185965A1 (en)
WO (1) WO2009056851A1 (en)
ZA (1) ZA201002751B (en)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
DE60318938T2 (en) 2002-03-20 2009-01-22 Mannkind Corp., Valencia INHALER
EP1786784B1 (en) 2004-08-20 2010-10-27 MannKind Corporation Catalysis of diketopiperazine synthesis
CA2578175C (en) 2004-08-23 2014-10-14 Mannkind Corporation Diketopiperazine salts, diketomorpholine salts or diketodioxane salts for drug delivery
US7803404B2 (en) 2005-09-14 2010-09-28 Mannkind Corporation Method of drug formulation based on increasing the affinity of active agents for crystalline microparticle surfaces
BRPI0707991B8 (en) 2006-02-22 2021-05-25 Mannkind Corp methods of preparing a dry powder medicine with an improved pharmaceutical property, said dry powder and using an effective amount of the dry powder
EP2570147B1 (en) 2008-06-13 2017-10-18 MannKind Corporation A dry powder inhaler and system for drug delivery
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
US9364619B2 (en) 2008-06-20 2016-06-14 Mannkind Corporation Interactive apparatus and method for real-time profiling of inhalation efforts
TWI614024B (en) 2008-08-11 2018-02-11 曼凱公司 Use of ultrarapid acting insulin
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
PL2405963T3 (en) 2009-03-11 2014-04-30 Mannkind Corp Apparatus, system and method for measuring resistance of an inhaler
KR20180079458A (en) 2009-06-12 2018-07-10 맨카인드 코포레이션 Diketopiperazine microparticles with defined specific surface areas
EP2496295A1 (en) 2009-11-03 2012-09-12 MannKind Corporation An apparatus and method for simulating inhalation efforts
RU2531455C2 (en) 2010-06-21 2014-10-20 Маннкайнд Корпорейшн Systems and methods for dry powder drugs delivery
TW201304822A (en) * 2010-11-15 2013-02-01 Vectura Ltd Compositions and uses
CN105667994B (en) 2011-04-01 2018-04-06 曼金德公司 Blister package for pharmaceutical kit
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
AU2012328885B2 (en) 2011-10-24 2017-08-31 Mannkind Corporation Methods and compositions for treating pain
SG10201703243QA (en) * 2012-02-28 2017-06-29 Iceutica Holdings Inc Inhalable pharmaceutical compositions
CN108057154B (en) 2012-07-12 2021-04-16 曼金德公司 Dry powder drug delivery system and method
CA2888979A1 (en) * 2012-10-22 2014-05-01 Civitas Therapeutics, Inc. Reducing inter-patient variability of levodopa plasma concentrations
US10159644B2 (en) 2012-10-26 2018-12-25 Mannkind Corporation Inhalable vaccine compositions and methods
CA2906817C (en) 2013-03-15 2022-01-18 Mannkind Corporation Microcrystalline diketopiperazine compositions and methods
GB201305825D0 (en) 2013-03-28 2013-05-15 Vectura Ltd New use
WO2014205030A1 (en) * 2013-06-19 2014-12-24 Map Pharmaceuticals, Inc. Pulmonary administration of rotigotine
WO2014205031A1 (en) * 2013-06-19 2014-12-24 Map Pharmaceuticals, Inc. Sustained-release formulation of rotigotine
US9925144B2 (en) 2013-07-18 2018-03-27 Mannkind Corporation Heat-stable dry powder pharmaceutical compositions and methods
JP2016530930A (en) 2013-08-05 2016-10-06 マンカインド コーポレイション Ventilation device and method
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
MA43042A (en) 2015-09-28 2018-08-08 Ever Neuro Pharma Gmbh AQUEOUS COMPOSITION OF APOMORPHINE FOR SUBCUTANEOUS ADMINISTRATION
EP3826620A4 (en) * 2018-07-12 2023-03-08 Arven Ilac Sanayi Ve Ticaret Anonim Sirketi Inhalation compositions comprising dopamine agonists
GB201912686D0 (en) * 2019-09-04 2019-10-16 Reown Pharma Inc Pharmaceutical composition
WO2023242355A1 (en) 2022-06-15 2023-12-21 Ever Neuro Pharma Gmbh Apomorphine prodrugs and uses thereof

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4742054A (en) * 1982-11-23 1988-05-03 Naftchi Nosrat E Treatment of mammals suffering from damage to the central nervous system
US5292520A (en) * 1990-09-13 1994-03-08 Akzo N.V. Stabilized solid pharmaceutical composition containing acid addition salts of a basic drug and an alkaline stabilizer
ATE290864T1 (en) * 1993-03-26 2005-04-15 Franciscus Wilhelmus He Merkus PHARMACEUTICAL COMPOSITIONS FOR INTRANASAL ADMINISTRATION OF DIHYDROERGOTAMIN
US6395744B1 (en) * 1994-04-22 2002-05-28 Queen's University At Kingston Method and compositions for the treatment or amelioration of female sexual dysfunction
US20020165122A1 (en) * 1994-04-22 2002-11-07 Heaton Jeremy P. W. Method and compositions for the treatment or amelioration of female sexual dysfunction
US6566368B2 (en) * 1994-04-22 2003-05-20 Pentech Pharmaceuticals, Inc. Apomorphine-containing dosage form for ameliorating male erectile dysfunction
DE69514794T2 (en) * 1994-04-22 2000-07-27 Pentech Pharmaceuticals Inc SUBLINGUAL DOSAGE FORMS CONTAINING APOMORPHIN FOR USE IN THE TREATMENT OF ERECTILE DYSFUNCTION
US5744476A (en) * 1994-06-27 1998-04-28 Interneuron Pharmaceuticals, Inc. Dopamine D1 agonists for the treatment of dementia
GB9501841D0 (en) * 1995-01-31 1995-03-22 Co Ordinated Drug Dev Improvements in and relating to carrier particles for use in dry powder inhalers
US6413496B1 (en) * 1996-12-04 2002-07-02 Biogland Ireland (R&D) Limited Pharmaceutical compositions and devices for their administration
US6193954B1 (en) * 1997-03-21 2001-02-27 Abbott Laboratories Formulations for pulmonary delivery of dopamine agonists
EP1035833B1 (en) * 1997-12-02 2005-08-31 Archimedes Development Limited Compositions for nasal administration
US20020002175A1 (en) * 2000-09-19 2002-01-03 Charanjit Behl Nasal delivery of apomorphine in combination with glycol derivatives
US6436950B1 (en) * 1998-08-14 2002-08-20 Nastech Pharmaceutical Company, Inc. Nasal delivery of apomorphine
US5994363A (en) * 1998-08-24 1999-11-30 Pentech Pharmaceuticals, Inc. Amelioration of apomorphine adverse effects
US6858199B1 (en) * 2000-06-09 2005-02-22 Advanced Inhalation Research, Inc. High efficient delivery of a large therapeutic mass aerosol
BR0005797A (en) * 2000-03-20 2001-10-16 Abbott Lab Methods for the treatment of sexual dysfunction with apomorphine at specified plasma concentration levels
GB0007193D0 (en) * 2000-03-25 2000-05-17 Univ Manchester Treatment of movrmrnt disorders
CZ20023637A3 (en) * 2000-04-07 2003-02-12 Tap Pharmaceutical Products, Inc. Apomorphine derivatives and methods of their use
US20040115133A1 (en) * 2000-05-10 2004-06-17 Wermeling Daniel P. Intranasal opioid compositions
SE0002934D0 (en) * 2000-08-17 2000-08-17 Axon Biochemicals Bv New aporphine esters and in their use in therapy
SE0102036D0 (en) * 2001-06-08 2001-06-08 Axon Biochemicals Bv Pharmaceutical formulation for the efficient administration of apomorphine, 6aR- (-) -N- Propyl- norapomorphine and their derivatives and pro-drugs thereof
US6613308B2 (en) * 2000-09-19 2003-09-02 Advanced Inhalation Research, Inc. Pulmonary delivery in treating disorders of the central nervous system
US6514482B1 (en) * 2000-09-19 2003-02-04 Advanced Inhalation Research, Inc. Pulmonary delivery in treating disorders of the central nervous system
US6528521B2 (en) * 2000-11-15 2003-03-04 Tap Pharmaceutical Products, Inc. Treatment of anti-depression drug-induced sexual dysfunction with apomorphine
US20020086876A1 (en) * 2000-11-15 2002-07-04 Ruff Dustin D. Treatment of anti-depression drug-induced sexual dysfunction with apomorphine
CA2434736A1 (en) * 2001-01-16 2002-07-25 Purdue Research Foundation Method of treatment of dopamine-related dysfunction through administration of a full d1 dopamine receptor agonist and with no induction of tolerance
CA2446904A1 (en) * 2001-05-24 2003-04-03 Alexza Molecular Delivery Corporation Delivery of drug esters through an inhalation route
US20040028613A1 (en) * 2001-06-25 2004-02-12 Nastech Pharmaceutical Company Inc Dopamine agonist formulations for enhanced central nervous system delivery
ITMI20012174A1 (en) * 2001-10-18 2003-04-18 Univ Parma POWDER FOR NASAL DRUG ADMINISTRATION
US20040204439A1 (en) * 2003-04-14 2004-10-14 Staniforth John Nicholas Composition, device, and method for treating sexual dysfunction via inhalation
BRPI0409380A (en) * 2003-04-14 2006-04-18 Vectura Ltd pharmaceutical compositions
CA2522158C (en) * 2003-04-14 2018-03-20 Vectura Ltd. Devices and pharmaceutical compositions for enhancing dosing efficiency
US20050090518A1 (en) * 2003-10-24 2005-04-28 Nastech Pharmaceutical Company Inc. Method for treating parkinson's disease using apomorphine and apomorphine prodrugs
GB0426301D0 (en) * 2004-11-30 2004-12-29 Vectura Ltd Pharmaceutical formulations

Also Published As

Publication number Publication date
RU2010121827A (en) 2011-12-10
KR20100091970A (en) 2010-08-19
GB0721394D0 (en) 2007-12-12
CN101932307A (en) 2010-12-29
ZA201002751B (en) 2011-06-29
RU2484823C2 (en) 2013-06-20
JP2011500869A (en) 2011-01-06
AU2008320569A1 (en) 2009-05-07
MX2010004614A (en) 2010-05-20
SG185965A1 (en) 2012-12-28
EP2214649A1 (en) 2010-08-11
AU2008320569B2 (en) 2014-01-30
CA2703063A1 (en) 2009-05-07
WO2009056851A1 (en) 2009-05-07
BRPI0818799A2 (en) 2015-04-22
IL205153A (en) 2014-11-30
NZ584622A (en) 2012-06-29
US20100288276A1 (en) 2010-11-18

Similar Documents

Publication Publication Date Title
ZA201002751B (en) Compositions for treating parkinson's disease
IL213259A0 (en) Composition for the use to treat alzheimer's disease
ZA201008484B (en) Rasagiline for parkinson's disease modification
IL209896A0 (en) Compounds for treating symptoms associated with parkinson's disease
ZA201100034B (en) Pharmaceutical compositions for treatment of parkinson's disease
PL2197883T3 (en) Catecholamine derivative useful for the treatment of parkinson's disease
PL2209458T3 (en) Skin treatment compositions
IL213120A0 (en) Method for treating parkinson' s disease
TWI367274B (en) Composition for fabric treatment
HK1154797A1 (en) Composition for treating disease
ZA201002213B (en) "6-pyrimidinyl-pyrimid-4-one derivative"
EP2473176A4 (en) Neuroprotective ganglioside compositions for use in treating or diagnosing huntington's disease
IL217149A0 (en) Compositions and methods for treating parkinson's disease
EP2174956A4 (en) Compositions for anti-fibrinolitic treatment
EP2151451A4 (en) Composition for preventing or treating lung disease
EP2043662A4 (en) Methods and compositions for treating disease
EP2214488A4 (en) Compositions and methods for treating parkinson's disease and related disorders
EP2517698A4 (en) Agent for treating parkinson's disease
EP2305629A4 (en) Therapeutic agent for alzheimer's disease
EP1863510A4 (en) Methods for treating parkinson's disease
EP2496080A4 (en) Methods for treating parkinson's disease
IL200192A0 (en) Composition useful for the treatment of type 2 diabetes
IL209804A0 (en) Pharmaceutical compositions for treatment of parkinson's disease
GB0717956D0 (en) 20's
GB0707113D0 (en) "Soote"- Sock boot

Legal Events

Date Code Title Description
FF Patent granted
MM9K Patent not in force due to non-payment of renewal fees