IL195348A0 - Crystalline form of (trans-4-[({5-[(3,4-difluorophenyl)amino]-1,3,4-oxadiazol-2-yl}carbonyl)amino]phenyl}cyclohexyl)acetic acid - Google Patents
Crystalline form of (trans-4-[({5-[(3,4-difluorophenyl)amino]-1,3,4-oxadiazol-2-yl}carbonyl)amino]phenyl}cyclohexyl)acetic acidInfo
- Publication number
- IL195348A0 IL195348A0 IL195348A IL19534808A IL195348A0 IL 195348 A0 IL195348 A0 IL 195348A0 IL 195348 A IL195348 A IL 195348A IL 19534808 A IL19534808 A IL 19534808A IL 195348 A0 IL195348 A0 IL 195348A0
- Authority
- IL
- Israel
- Prior art keywords
- amino
- oxadiazol
- difluorophenyl
- cyclohexyl
- trans
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/10—1,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles
- C07D271/113—1,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4245—Oxadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Neurology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Virology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- AIDS & HIV (AREA)
- Emergency Medicine (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Oncology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0611552.1A GB0611552D0 (en) | 2006-06-12 | 2006-06-12 | Chemical compounds |
PCT/GB2007/002097 WO2007144571A1 (en) | 2006-06-12 | 2007-06-08 | Crystalline form of (trans-4- [ ( { 5- [ (3, 4 -di fluorophenyl) amino] -1,3, 4-oxadiazol-2-yl}carbonyl) amino] ph enyl } cyclohexyl) acetic acid |
Publications (1)
Publication Number | Publication Date |
---|---|
IL195348A0 true IL195348A0 (en) | 2009-08-03 |
Family
ID=36745696
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL195348A IL195348A0 (en) | 2006-06-12 | 2008-11-17 | Crystalline form of (trans-4-[({5-[(3,4-difluorophenyl)amino]-1,3,4-oxadiazol-2-yl}carbonyl)amino]phenyl}cyclohexyl)acetic acid |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP2041101A1 (en) |
JP (1) | JP2009539954A (en) |
KR (1) | KR20090015980A (en) |
CN (1) | CN101466690A (en) |
AR (1) | AR061332A1 (en) |
AU (1) | AU2007259031A1 (en) |
BR (1) | BRPI0712354A2 (en) |
CA (1) | CA2653550A1 (en) |
CL (1) | CL2007001700A1 (en) |
GB (1) | GB0611552D0 (en) |
IL (1) | IL195348A0 (en) |
MX (1) | MX2008015762A (en) |
NO (1) | NO20084963L (en) |
TW (1) | TW200815378A (en) |
UY (1) | UY30404A1 (en) |
WO (1) | WO2007144571A1 (en) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BRPI0519058A2 (en) | 2004-12-14 | 2008-12-23 | Astrazeneca Ab | compound or a pharmaceutically acceptable prodrug salt thereof, methods for producing an inhibition of dgat1 activity and for treating diabetes mellitus and / or obesity in a warm-blooded animal, use of a compound, pharmaceutical composition, and process for preparing a compound |
WO2007071966A1 (en) | 2005-12-22 | 2007-06-28 | Astrazeneca Ab | Pyrimido- [4, 5-b] -oxazines for use as dgat inhibitors |
KR101456721B1 (en) | 2006-03-31 | 2014-10-31 | 노파르티스 아게 | New compounds |
MX2008015226A (en) | 2006-05-30 | 2008-12-12 | Astrazeneca Ab | 1, 3, 4 -oxadiazole derivatives as dgat1 inhibitors. |
ATE492541T1 (en) | 2006-05-30 | 2011-01-15 | Astrazeneca Ab | SUBSTITUTED 5-PHENYLAMINO-1,3,4-OXADIAZOLE-2-YLCARBONYLAMINO-4-PHENOXYCYCLOHEXANECARBONY ACIDS AS INHIBITORS OF ACETYLCOENZYME-A-DIACYLGLYCEROLACYLTRANSFERASE |
EP2120911A1 (en) * | 2007-02-15 | 2009-11-25 | Prosidion Limited | Amide and urea derivatives for the treatment of metabolic diseases |
AR066169A1 (en) | 2007-09-28 | 2009-07-29 | Novartis Ag | DERIVATIVES OF BENZO-IMIDAZOLES, USEFUL FOR DISORDERS ASSOCIATED WITH THE ACTIVITY OF DGAT |
BRPI0821274A2 (en) | 2007-12-20 | 2017-06-13 | Astrazeneca Ab | compound or a pharmaceutically acceptable salt or prodrug thereof, use thereof, method for treating a disease in a warm-blooded animal, and pharmaceutical composition |
EP2408774B1 (en) | 2009-03-20 | 2014-11-26 | Metabasis Therapeutics, Inc. | Inhibitors of diacylglycerol o-acyltransferase 1(dgat-1) and uses thereof |
EP2443096A1 (en) | 2009-06-19 | 2012-04-25 | AstraZeneca AB | Pyrazine carboxamides as inhibitors of dgat1 |
FR2963005B1 (en) * | 2010-07-23 | 2012-08-17 | Sanofi Aventis | DERIVATIVES OF OXADIAZOLES AND PYRIDAZINES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR044152A1 (en) * | 2003-05-09 | 2005-08-24 | Bayer Corp | RENTAL DERIVATIVES, METHOD OF PREPARATION AND USE FOR THE TREATMENT OF OBESITY |
BRPI0519058A2 (en) * | 2004-12-14 | 2008-12-23 | Astrazeneca Ab | compound or a pharmaceutically acceptable prodrug salt thereof, methods for producing an inhibition of dgat1 activity and for treating diabetes mellitus and / or obesity in a warm-blooded animal, use of a compound, pharmaceutical composition, and process for preparing a compound |
-
2006
- 2006-06-12 GB GBGB0611552.1A patent/GB0611552D0/en not_active Ceased
-
2007
- 2007-06-04 TW TW096120008A patent/TW200815378A/en unknown
- 2007-06-08 BR BRPI0712354-0A patent/BRPI0712354A2/en not_active Application Discontinuation
- 2007-06-08 CN CNA2007800217295A patent/CN101466690A/en active Pending
- 2007-06-08 JP JP2009514875A patent/JP2009539954A/en active Pending
- 2007-06-08 MX MX2008015762A patent/MX2008015762A/en not_active Application Discontinuation
- 2007-06-08 CA CA002653550A patent/CA2653550A1/en not_active Abandoned
- 2007-06-08 EP EP07733109A patent/EP2041101A1/en not_active Withdrawn
- 2007-06-08 KR KR1020087030959A patent/KR20090015980A/en not_active Application Discontinuation
- 2007-06-08 AU AU2007259031A patent/AU2007259031A1/en not_active Abandoned
- 2007-06-08 WO PCT/GB2007/002097 patent/WO2007144571A1/en active Application Filing
- 2007-06-11 CL CL2007001700A patent/CL2007001700A1/en unknown
- 2007-06-11 AR ARP070102537A patent/AR061332A1/en not_active Application Discontinuation
- 2007-06-11 UY UY30404A patent/UY30404A1/en not_active Application Discontinuation
-
2008
- 2008-11-17 IL IL195348A patent/IL195348A0/en unknown
- 2008-11-26 NO NO20084963A patent/NO20084963L/en unknown
Also Published As
Publication number | Publication date |
---|---|
CA2653550A1 (en) | 2007-12-21 |
EP2041101A1 (en) | 2009-04-01 |
MX2008015762A (en) | 2009-03-16 |
NO20084963L (en) | 2009-01-07 |
UY30404A1 (en) | 2008-01-31 |
JP2009539954A (en) | 2009-11-19 |
BRPI0712354A2 (en) | 2012-06-05 |
TW200815378A (en) | 2008-04-01 |
KR20090015980A (en) | 2009-02-12 |
WO2007144571A1 (en) | 2007-12-21 |
GB0611552D0 (en) | 2006-07-19 |
AR061332A1 (en) | 2008-08-20 |
CN101466690A (en) | 2009-06-24 |
CL2007001700A1 (en) | 2008-01-18 |
AU2007259031A1 (en) | 2007-12-21 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL195348A0 (en) | Crystalline form of (trans-4-[({5-[(3,4-difluorophenyl)amino]-1,3,4-oxadiazol-2-yl}carbonyl)amino]phenyl}cyclohexyl)acetic acid | |
IL245688A0 (en) | Crystalline solvates and complexes of (1s) -1, 5-anhydro-1-c- (3- ( (phenyl) methyl) phenyl) -d-glucitol derivatives with amino acids as sglt2 inhibitors for the treatment of diabetes | |
IL223002A0 (en) | Crystalline form of 4- [5 - [3 -chloro-5 - (trifluoromethyl) phenyl] -4, 5 - dihydro - 5 - (trifluoromethyl) -3 - isoxazolyl] -n- [2-0x0-2- [ ( 2, 2, 2 - trifluoroethyl) amino] ethyl] -1- naphthalenecarboxamide | |
SI2097381T1 (en) | 4-S4-(sS4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL)CCARBAMOYLcAMINO)-3-FLUOROPHENOXYC-N-METHYLPYRIDINE-2-CARBOXAMIDE MONOHYDRATE | |
TWI372669B (en) | Fill head for injection molding of solder | |
IL209431A0 (en) | Novel salts of (4-{[(5-{[(3-chlorophenyl)methyl]oxy}-2-methylphenyl)carbonyl]amino}-3-methylphenyl)acetic acid | |
IL187421A0 (en) | Process for the synthesis of 5-(methyl-1h-imidazol-1-yl)-3-(tri fluorome th yl)-benzeneamine | |
IL197448A0 (en) | Methods for administering long-lasting hypoglycemic agents | |
IL216655A0 (en) | Trans-4-[[(5s)-5-[[[3,5-bis(trifluoromethyl)phenyl]methyl] (2-methyl-2h-tetrazol-5-yl)amino]-2,3,4,5-tetahydro-7,9-dimethyl-1h-1-benzazepin-1-yl]methyl]-cyclohexanecarboxylic acid | |
FR2933454B1 (en) | INJECTION MODULE FOR INJECTION VALVE | |
PL2081980T3 (en) | Temperature-sensitive active ingredient compositions for reducing the density of plastics | |
IL209430A0 (en) | Novel polymorphic forms of (4-{[(5-{[(3-chlorophenyl)methyl]oxy}-2-methylphenyl)carbonyl]amino}-3-methylphenyl)acetic acid | |
EP2064044A4 (en) | Injection molded product | |
PL2032533T3 (en) | Process for making n-hydroxy-3-ý4-ýýý2-(2-methyl-1h-indol-3-yl)ethyl¨amino¨methyl¨phenyl¨-2e-2-propenamide and starting materials therefor | |
EP2089209A4 (en) | Injection molding process | |
GB0607048D0 (en) | Air pump for aquariums | |
AU2006201692A1 (en) | Modifying the weld line of an injection moulding | |
PL2435406T3 (en) | Resolution of (±)-methyl phenyl[4-[4-[[[4'-(trifluoromethyl)-2-biphenylyl]carbonyl]amino]phenyl]-1-piperidinyl]acetate | |
AU2006903736A0 (en) | Improved Aquaculture Growing System | |
AU2006901593A0 (en) | Injection of solids |