IL180706A0 - Pharmaceutical dosage forms including rasagiline - Google Patents

Pharmaceutical dosage forms including rasagiline

Info

Publication number
IL180706A0
IL180706A0 IL180706A IL18070607A IL180706A0 IL 180706 A0 IL180706 A0 IL 180706A0 IL 180706 A IL180706 A IL 180706A IL 18070607 A IL18070607 A IL 18070607A IL 180706 A0 IL180706 A0 IL 180706A0
Authority
IL
Israel
Prior art keywords
dosage forms
pharmaceutical dosage
forms including
rasagiline
including rasagiline
Prior art date
Application number
IL180706A
Original Assignee
Teva Pharma
Fleshner Barak Moshe
Lerner Itzhak
Rosenberger Vered
Aqua Ofer
Gilbert Adrian
Licht Daniela
Patashnik Shulamit
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Pharma, Fleshner Barak Moshe, Lerner Itzhak, Rosenberger Vered, Aqua Ofer, Gilbert Adrian, Licht Daniela, Patashnik Shulamit filed Critical Teva Pharma
Publication of IL180706A0 publication Critical patent/IL180706A0/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL180706A 2004-07-26 2007-01-15 Pharmaceutical dosage forms including rasagiline IL180706A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US59135904P 2004-07-26 2004-07-26
US60624104P 2004-09-01 2004-09-01
PCT/US2005/026517 WO2006014973A2 (en) 2004-07-26 2005-07-26 Pharmaceutical dosage forms including rasagiline

Publications (1)

Publication Number Publication Date
IL180706A0 true IL180706A0 (en) 2007-06-03

Family

ID=35787777

Family Applications (1)

Application Number Title Priority Date Filing Date
IL180706A IL180706A0 (en) 2004-07-26 2007-01-15 Pharmaceutical dosage forms including rasagiline

Country Status (7)

Country Link
US (1) US20060018957A1 (en)
EP (1) EP1778196A4 (en)
JP (1) JP2008507586A (en)
AU (1) AU2005269416B2 (en)
CA (1) CA2574925A1 (en)
IL (1) IL180706A0 (en)
WO (1) WO2006014973A2 (en)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2588780T3 (en) 2002-11-15 2016-11-04 Teva Pharmaceutical Industries Limited Use of rasagiline with or without riluzole for the treatment of amyotrophic lateral sclerosis
RU2389482C2 (en) * 2004-11-24 2010-05-20 Тева Фармасьютикал Индастриз, Лтд. Rasagiline compositions degrading in mouth cavity
RS52867B (en) * 2005-02-17 2013-12-31 Teva Pharmaceutical Industries Ltd. Combination therapy with glatiramer acetate and rasagiline for the treatment of multiple sclerosis
MX2007010233A (en) * 2005-02-23 2007-11-07 Teva Pharma Rasagiline formulations of improved content uniformity.
EP1954667B1 (en) * 2005-11-17 2017-02-08 Teva Pharmaceutical Industries Ltd Methods for isolating propargylated aminoindans
US7572834B1 (en) 2005-12-06 2009-08-11 Teva Pharmaceutical Industries, Ltd. Rasagiline formulations and processes for their preparation
WO2007098264A2 (en) 2006-02-21 2007-08-30 Teva Pharmaceutical Industries, Ltd. Use of rasagiline for the treatment of multiple system atrophy
CA2646250A1 (en) * 2006-04-03 2007-10-18 Teva Pharmaceutical Industries Ltd. Use of rasagiline for the treatment of restless legs syndrome
US7807715B2 (en) * 2006-06-09 2010-10-05 Ucb Pharma Gmbh Pharmaceutical compositions comprising fesoterodine
EP1892233A1 (en) 2006-08-18 2008-02-27 Ratiopharm GmbH New salts of the active component rasagiline
JP5623081B2 (en) * 2006-12-14 2014-11-12 テバ ファーマシューティカル インダストリーズ リミティド Crystalline solid rasagiline base
AU2007334493B2 (en) * 2006-12-14 2010-12-02 Teva Pharmaceutical Industries, Ltd. Tannate salt of rasagiline
US20100303901A1 (en) * 2007-04-26 2010-12-02 Eyal Shimoni Oral delivery of proteins and peptides
EP1987816A1 (en) * 2007-04-30 2008-11-05 Ratiopharm GmbH Adsorbate of a rasagiline salt with a water-soluble inactive ingredient
EP2194780A4 (en) * 2007-09-05 2010-10-27 Teva Pharma Method of treating glaucoma using rasagiline
US8188149B2 (en) * 2007-09-17 2012-05-29 Teva Pharmaceutical Industries, Ltd. Use of R(+)-N-propargy1-1-aminoindan to treat or prevent hearing loss
NZ586025A (en) * 2008-01-11 2012-08-31 Teva Pharma Rasagiline mesylate tablet coated with a composisiton comprising methacrylic acid - ethyl acrylate copolymer and triethyl citrate
WO2009151594A1 (en) * 2008-06-10 2009-12-17 Teva Pharmaceutical Industries, Ltd. Rasagiline soft gelatin capsules
JP2011522892A (en) * 2008-06-13 2011-08-04 テバ ファーマシューティカル インダストリーズ リミティド Rasagiline for relieving Parkinson's disease
BRPI0909997A2 (en) 2008-06-19 2015-10-27 Teva Pharma crystalline r (+) - n-propargyl-1-aminoindan, pharmaceutical composition, drying process solid r (+) - n-propargyl-1-aminoindan, preparation of a pharmaceutical composition, validated batch production process of a drug product containing crystalline r (+) - n-propargyl-1-aminoindane and at least one pharmaceutically acceptable carrier for delivery and prudential process of crystalline r (+) - n-propargyl-1-aminoindane
CA2727021A1 (en) * 2008-06-19 2009-12-23 Teva Pharmaceutical Industries Ltd. Process for purifying rasagiline base
US20110172249A1 (en) 2008-09-03 2011-07-14 Takeda Pharmaceutical Company Limted Method for improving absorbability of preparation, and preparation having improved absorbability
DE102008064061A1 (en) * 2008-12-19 2010-06-24 Ratiopharm Gmbh Solid composition with the active ingredient rasagiline
US20100189790A1 (en) 2009-01-23 2010-07-29 Teva Pharmaceutical Industries, Ltd. Delayed release rasagiline formulation
EP2218444A3 (en) 2009-01-23 2010-08-25 Teva Pharmaceutical Industries, Ltd. Delayed release rasagiline formulation
CN102341104A (en) * 2009-03-05 2012-02-01 桑多斯股份公司 Pharmaceutical composition containing 1h-inden-1-amine, 2,3-dihydro-n-2-propynyl-, (1r)-, methanesulfonate
WO2010111264A2 (en) * 2009-03-24 2010-09-30 Dr. Reddy's Laboratories Ltd. Rasagiline formulations
JP2012532843A (en) 2009-07-09 2012-12-20 ラティオファーム ゲーエムベーハー Rasagiline salt and preparation thereof
AU2010341499A1 (en) 2009-12-22 2012-08-09 Teva Pharmaceutical Industries Ltd. 3-keto-N-propargyl-1-aminoindan
EP3517103A1 (en) * 2010-02-03 2019-07-31 Pharma Two B Ltd. Extended release formulations of rasagiline and uses thereof
US9205577B2 (en) * 2010-02-05 2015-12-08 Allergan, Inc. Porogen compositions, methods of making and uses
US9138309B2 (en) 2010-02-05 2015-09-22 Allergan, Inc. Porous materials, methods of making and uses
US8920840B2 (en) 2010-04-30 2014-12-30 Takeda Pharmaceutical Company Limited Enteric tablet
EA030433B1 (en) 2010-04-30 2018-08-31 Такеда Фармасьютикал Компани Лимитед Enteric tablet
US11202853B2 (en) * 2010-05-11 2021-12-21 Allergan, Inc. Porogen compositions, methods of making and uses
EP2389927A1 (en) * 2010-05-30 2011-11-30 Abdi Ibrahim Ilac Sanayi ve Ticaret Anonim Sirketi Pharmaceutical formulations of rasagiline
AU2011282716A1 (en) 2010-07-27 2013-03-14 Teva Pharmaceutical Industries Ltd. Dispersions of rasagiline citrate
CA2806740A1 (en) 2010-07-27 2012-02-02 Teva Pharmaceutical Industries Ltd. Use of rasagiline for the treatment of olfactory dysfunction
JP2014503480A (en) * 2010-10-26 2014-02-13 テバ ファーマシューティカル インダストリーズ リミティド Deuterium-rich rasagiline
AU2012323349A1 (en) 2011-10-10 2014-05-22 Teva Pharmaceutical Industries Ltd. R(+)-N-formyl-propargyl-aminoindan
BR112014008552A2 (en) 2011-10-10 2017-04-18 Teva Pharma r (+) - n-methylpropargylaminoindane
US9504657B2 (en) 2012-01-12 2016-11-29 Pharmatwob Ltd. Fixed dose combination therapy of Parkinson's disease
US20150079187A1 (en) * 2012-01-12 2015-03-19 Pharma Two B Ltd. Fixed dose combination therapy of parkinson's disease
JP2015529196A (en) 2012-08-17 2015-10-05 テバ ファーマシューティカル インダストリーズ リミティド Rasagiline parenteral formulation
ES2524865T1 (en) * 2013-02-06 2014-12-15 Galenicum Health S.L. Stable pharmaceutical compositions in the form of immediate-release tablets
ES2502140T1 (en) * 2013-02-06 2014-10-02 Galenicum Health S.L. Rasagiline hemitartrate immediate-release tablets
IN2013MU01782A (en) * 2013-05-20 2015-06-26 Cadila Healthcare Ltd

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US20040052843A1 (en) * 2001-12-24 2004-03-18 Lerner E. Itzhak Controlled release dosage forms
NZ534104A (en) * 2001-12-24 2007-03-30 Teva Pharma Dosage form with a core tablet of active ingredient sheathed in a compressed annular body of powder or granular material
US20040010038A1 (en) * 2002-02-27 2004-01-15 Eran Blaugrund Propargylamino indan derivatives and propargylamino tetralin derivatives as brain-selective MAO inhibitors
JP2005525377A (en) * 2002-03-04 2005-08-25 サマセット ファーマシューティカルズ， インコーポレイテッド Method for prevention and treatment of peripheral neuropathy by administration of desmethyl selegiline
US20040166159A1 (en) * 2002-05-29 2004-08-26 Chien-Hsuan Han Pharmaceutical dosage forms having immediate and controlled release properties that contain an aromatic amino acid decarboxylase inhibitor and levodopa
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ES2588780T3 (en) * 2002-11-15 2016-11-04 Teva Pharmaceutical Industries Limited Use of rasagiline with or without riluzole for the treatment of amyotrophic lateral sclerosis
US7735024B2 (en) * 2003-10-29 2010-06-08 Intel Corporation Methods and apparatus to provide a handheld pointer-based user interface
US20090111892A1 (en) * 2004-11-24 2009-04-30 Shulamit Patashnik Rasagiline Orally Disintegrating Compositions
MX2007010233A (en) * 2005-02-23 2007-11-07 Teva Pharma Rasagiline formulations of improved content uniformity.
EP1954667B1 (en) * 2005-11-17 2017-02-08 Teva Pharmaceutical Industries Ltd Methods for isolating propargylated aminoindans
US7572834B1 (en) * 2005-12-06 2009-08-11 Teva Pharmaceutical Industries, Ltd. Rasagiline formulations and processes for their preparation
WO2007098264A2 (en) * 2006-02-21 2007-08-30 Teva Pharmaceutical Industries, Ltd. Use of rasagiline for the treatment of multiple system atrophy
CA2646250A1 (en) * 2006-04-03 2007-10-18 Teva Pharmaceutical Industries Ltd. Use of rasagiline for the treatment of restless legs syndrome
EP1892233A1 (en) * 2006-08-18 2008-02-27 Ratiopharm GmbH New salts of the active component rasagiline
AU2007334493B2 (en) * 2006-12-14 2010-12-02 Teva Pharmaceutical Industries, Ltd. Tannate salt of rasagiline
JP5623081B2 (en) * 2006-12-14 2014-11-12 テバ ファーマシューティカル インダストリーズ リミティド Crystalline solid rasagiline base
EP1987816A1 (en) * 2007-04-30 2008-11-05 Ratiopharm GmbH Adsorbate of a rasagiline salt with a water-soluble inactive ingredient
EP2194780A4 (en) * 2007-09-05 2010-10-27 Teva Pharma Method of treating glaucoma using rasagiline
US8188149B2 (en) * 2007-09-17 2012-05-29 Teva Pharmaceutical Industries, Ltd. Use of R(+)-N-propargy1-1-aminoindan to treat or prevent hearing loss
NZ586025A (en) * 2008-01-11 2012-08-31 Teva Pharma Rasagiline mesylate tablet coated with a composisiton comprising methacrylic acid - ethyl acrylate copolymer and triethyl citrate
WO2009151594A1 (en) * 2008-06-10 2009-12-17 Teva Pharmaceutical Industries, Ltd. Rasagiline soft gelatin capsules
JP2011522892A (en) * 2008-06-13 2011-08-04 テバ ファーマシューティカル インダストリーズ リミティド Rasagiline for relieving Parkinson's disease
BRPI0909997A2 (en) * 2008-06-19 2015-10-27 Teva Pharma crystalline r (+) - n-propargyl-1-aminoindan, pharmaceutical composition, drying process solid r (+) - n-propargyl-1-aminoindan, preparation of a pharmaceutical composition, validated batch production process of a drug product containing crystalline r (+) - n-propargyl-1-aminoindane and at least one pharmaceutically acceptable carrier for delivery and prudential process of crystalline r (+) - n-propargyl-1-aminoindane
CA2727021A1 (en) * 2008-06-19 2009-12-23 Teva Pharmaceutical Industries Ltd. Process for purifying rasagiline base
WO2011012140A2 (en) * 2008-07-11 2011-02-03 Synthon Bv Polymorphs of rasagiline hydrochloride
US20100029987A1 (en) * 2008-07-29 2010-02-04 Dipharma Francis S.R.I. Crystalline Form of Rasagiline and Process for the Preparation Thereof
US20100189790A1 (en) * 2009-01-23 2010-07-29 Teva Pharmaceutical Industries, Ltd. Delayed release rasagiline formulation

Also Published As

Publication number Publication date
EP1778196A4 (en) 2008-12-17
EP1778196A2 (en) 2007-05-02
US20060018957A1 (en) 2006-01-26
AU2005269416B2 (en) 2011-07-28
WO2006014973A3 (en) 2006-04-13
JP2008507586A (en) 2008-03-13
WO2006014973A2 (en) 2006-02-09
AU2005269416A1 (en) 2006-02-09
CA2574925A1 (en) 2006-02-09

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