IL164552A0 - Binary or polynary targeting and uses thereof - Google Patents
Binary or polynary targeting and uses thereofInfo
- Publication number
- IL164552A0 IL164552A0 IL16455204A IL16455204A IL164552A0 IL 164552 A0 IL164552 A0 IL 164552A0 IL 16455204 A IL16455204 A IL 16455204A IL 16455204 A IL16455204 A IL 16455204A IL 164552 A0 IL164552 A0 IL 164552A0
- Authority
- IL
- Israel
- Prior art keywords
- binary
- polynary
- targeting
- polynary targeting
- Prior art date
Links
- 230000008685 targeting Effects 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y10/00—Nanotechnology for information processing, storage or transmission, e.g. quantum computing or single electron logic
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/972—Modified antibody, e.g. hybrid, bifunctional
Landscapes
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Nanotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- Pharmacology & Pharmacy (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Theoretical Computer Science (AREA)
- Cell Biology (AREA)
- Mathematical Physics (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Food Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pathology (AREA)
- Public Health (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US37706702P | 2002-05-01 | 2002-05-01 | |
| PCT/US2003/013637 WO2003093793A2 (en) | 2002-05-01 | 2003-04-30 | Binary or polynary targeting and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL164552A0 true IL164552A0 (en) | 2005-12-18 |
Family
ID=29401442
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL16455204A IL164552A0 (en) | 2002-05-01 | 2004-10-13 | Binary or polynary targeting and uses thereof |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US6867007B2 (de) |
| EP (1) | EP1497466A4 (de) |
| JP (1) | JP2005538049A (de) |
| AU (1) | AU2003234327B2 (de) |
| CA (1) | CA2482967A1 (de) |
| IL (1) | IL164552A0 (de) |
| WO (1) | WO2003093793A2 (de) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2004287894B2 (en) * | 2003-11-07 | 2009-01-29 | Hepgenics Pty Ltd | Binding assay components |
| JP2007510165A (ja) * | 2003-11-07 | 2007-04-19 | ヘプゲニクス ピーティワイ リミティッド | 結合アッセイ成分 |
| US7973134B2 (en) * | 2004-07-07 | 2011-07-05 | Cell Signaling Technology, Inc. | Reagents for the detection of protein phosphorylation in anaplastic large cell lymphoma signaling pathways |
| US7935790B2 (en) * | 2004-10-04 | 2011-05-03 | Cell Singaling Technology, Inc. | Reagents for the detection of protein phosphorylation in T-cell receptor signaling pathways |
| US7807789B2 (en) * | 2004-12-21 | 2010-10-05 | Cell Signaling Technology, Inc. | Reagents for the detection of protein phosphorylation in EGFR-signaling pathways |
| US20090099340A1 (en) * | 2007-10-12 | 2009-04-16 | Cell Signaling Technology, Inc. | Reagents for the detection of protein phosphorylation in carcinoma signaling pathways |
| EP1934867A2 (de) * | 2005-08-31 | 2008-06-25 | Cell Signaling Technology, Inc. | Reagentien zum nachweis der proteinphosphorylierung in leukämie-signalwegen |
| US20100151495A9 (en) * | 2005-08-31 | 2010-06-17 | Cell Signaling Technolgy, Inc. | Reagents for the detection of protein phosphorylation in carcinoma signaling pathways |
| US20090298093A1 (en) * | 2006-04-27 | 2009-12-03 | Roberto Polakiewicz | Reagents for the Detection of Protein Phosphorylation in ATM & ATR Kinase Signaling Pathways |
| US7939636B2 (en) * | 2006-08-11 | 2011-05-10 | Cell Signaling Technology, Inc. | Reagents for the detection of protein phosphorylation in c-Src signaling pathways |
| US20090258442A1 (en) * | 2006-08-31 | 2009-10-15 | Cell Signaling Technology, Inc. | Reagents for the detection of protein phosphorylation in carcinoma signaling pathways |
| RU2009120007A (ru) * | 2006-10-27 | 2010-12-10 | Трастиз Оф Бостон Юниверсити (Us) | Направленные конъюгаты с разделенными биомолекулами для лечения заболеваний, злокачественных образований и нарушений и способы их получения |
| US20090081659A1 (en) | 2007-03-07 | 2009-03-26 | Cell Signaling Technology, Inc. | Reagents for the detection of protein phosphorylation in carcinoma signaling pathways |
| US20090068684A1 (en) * | 2007-03-26 | 2009-03-12 | Cell Signaling Technology, Inc. | Serine and threoninephosphorylation sites |
| US20080238709A1 (en) * | 2007-03-28 | 2008-10-02 | Faramarz Vaziri | One-way communication apparatus with dynamic key generation |
| EP2145902A3 (de) | 2007-04-19 | 2010-09-29 | Peter Hornbeck | Tyrosinphosphorylations-Stellen und spezifische Antikörper |
| US7977462B2 (en) | 2007-04-19 | 2011-07-12 | Cell Signaling Technology, Inc. | Tyrosine phosphorylation sites |
| EP1983003A3 (de) | 2007-04-19 | 2009-03-11 | Peter Hornbeck | Tyrosinphosphorylationsstellen und spezifische Antikörper |
| US20090053831A1 (en) | 2007-05-01 | 2009-02-26 | Cell Signaling Technology, Inc. | Tyrosine phosphorylation sites |
| US20090203043A1 (en) | 2007-11-21 | 2009-08-13 | Peter Hornbeck | Protein phosphorylation by basophilic serine/threonine kinases in insulin signaling pathways |
| US20090220991A1 (en) * | 2008-02-29 | 2009-09-03 | Cell Signaling Technology, Inc. | Reagents for the detection of protein phosphorylation in leukemia signaling pathways |
| EP3023502A1 (de) | 2008-04-10 | 2016-05-25 | Cell Signaling Technology, Inc. | Zusammensetzungen und verfahren zur erkennung von egfr-mutationen bei krebs |
| US8148088B2 (en) * | 2008-07-18 | 2012-04-03 | Abgent | Regulation of autophagy pathway phosphorylation and uses thereof |
| US8735175B2 (en) | 2011-03-18 | 2014-05-27 | Chris D. Geddes | Multicolor microwave-accelerated metal-enhanced fluorescence (M-MAMEF) |
| CN103543260A (zh) * | 2013-07-30 | 2014-01-29 | 中国检验检疫科学研究院 | 一种基于磁分离-量子点免疫荧光传感检测生物大分子的方法及其试剂制备方法 |
| AR099812A1 (es) | 2014-03-21 | 2016-08-17 | Abbvie Inc | Anticuerpos y conjugados de anticuerpo y fármaco anti-egfr |
| AU2017279550A1 (en) | 2016-06-08 | 2019-01-03 | Abbvie Inc. | Anti-B7-H3 antibodies and antibody drug conjugates |
| WO2017214322A1 (en) | 2016-06-08 | 2017-12-14 | Abbvie Inc. | Anti-b7-h3 antibodies and antibody drug conjugates |
| JP2019524651A (ja) | 2016-06-08 | 2019-09-05 | アッヴィ・インコーポレイテッド | 抗cd98抗体及び抗体薬物コンジュゲート |
| MX2018015285A (es) | 2016-06-08 | 2019-09-18 | Abbvie Inc | Anticuerpos anti-b7-h3 y conjugados de anticuerpo y farmaco. |
| EP3554544A4 (de) | 2016-12-16 | 2020-07-29 | Bluefin Biomedicine, Inc. | Anti-cub-haltige protein 1-(cdcp1)-antikörper, antikörper-wirkstoff-konjugate und verfahren zur verwendung davon |
| EP3612567B1 (de) | 2017-04-19 | 2024-09-11 | Bluefin Biomedicine, Inc. | Anti-vtcn1-antikörper und antikörper-wirkstoff-konjugate |
| CA3066918A1 (en) | 2017-06-12 | 2018-12-20 | Bluefin Biomedicine, Inc. | Anti-il1rap antibodies and antibody drug conjugates |
| AR124681A1 (es) | 2021-01-20 | 2023-04-26 | Abbvie Inc | Conjugados anticuerpo-fármaco anti-egfr |
| WO2025027529A1 (en) | 2023-07-31 | 2025-02-06 | Advesya | Anti-il-1rap antibody drug conjugates and methods of use thereof |
| TW202530255A (zh) | 2023-12-15 | 2025-08-01 | 法商亞維西亞有限公司 | 抗il-1rap結合結構域及其抗體-藥物偶聯物 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4444879A (en) * | 1981-01-29 | 1984-04-24 | Science Research Center, Inc. | Immunoassay with article having support film and immunological counterpart of analyte |
| US4988617A (en) * | 1988-03-25 | 1991-01-29 | California Institute Of Technology | Method of detecting a nucleotide change in nucleic acids |
| US5612034A (en) * | 1990-10-03 | 1997-03-18 | Redcell, Inc. | Super-globuling for in vivo extended lifetimes |
| EP0787185A2 (de) * | 1994-10-20 | 1997-08-06 | MorphoSys AG | Gezielte heterozusammensetzung von rekombinanten proteinen bei multifunktionalen komplexen |
| US6372427B1 (en) * | 1995-04-12 | 2002-04-16 | Hybridon, Inc. | Cooperative oligonucleotides |
| US5981199A (en) * | 1996-06-14 | 1999-11-09 | Boehringer Mannheim Corporation | Method for measuring antigen concentration |
| CA2196496A1 (en) * | 1997-01-31 | 1998-07-31 | Stephen William Watson Michnick | Protein fragment complementation assay for the detection of protein-protein interactions |
| US20030103984A1 (en) * | 1998-05-04 | 2003-06-05 | Heinz Kohler | Fusion proteins of biologically active peptides and antibodies |
| US6511809B2 (en) * | 2000-06-13 | 2003-01-28 | E. I. Du Pont De Nemours And Company | Method for the detection of an analyte by means of a nucleic acid reporter |
| US20030157091A1 (en) * | 2002-02-14 | 2003-08-21 | Dyax Corporation | Multi-functional proteins |
-
2003
- 2003-04-30 CA CA002482967A patent/CA2482967A1/en not_active Abandoned
- 2003-04-30 WO PCT/US2003/013637 patent/WO2003093793A2/en not_active Ceased
- 2003-04-30 EP EP03728641A patent/EP1497466A4/de not_active Withdrawn
- 2003-04-30 US US10/427,755 patent/US6867007B2/en not_active Expired - Lifetime
- 2003-04-30 AU AU2003234327A patent/AU2003234327B2/en not_active Ceased
- 2003-04-30 JP JP2004501909A patent/JP2005538049A/ja active Pending
-
2004
- 2004-10-13 IL IL16455204A patent/IL164552A0/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2003093793A2 (en) | 2003-11-13 |
| WO2003093793A3 (en) | 2004-10-21 |
| US20040033519A1 (en) | 2004-02-19 |
| EP1497466A4 (de) | 2007-11-14 |
| AU2003234327B2 (en) | 2008-05-29 |
| CA2482967A1 (en) | 2003-11-13 |
| AU2003234327A1 (en) | 2003-11-17 |
| US6867007B2 (en) | 2005-03-15 |
| JP2005538049A (ja) | 2005-12-15 |
| EP1497466A2 (de) | 2005-01-19 |
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