IL164358A0 - Broad-spectrum in-vivo effective superantigen toxin antagonists based on the interaction between cd28 and the superantigen and uses thereof - Google Patents

Broad-spectrum in-vivo effective superantigen toxin antagonists based on the interaction between cd28 and the superantigen and uses thereof

Info

Publication number
IL164358A0
IL164358A0 IL16435803A IL16435803A IL164358A0 IL 164358 A0 IL164358 A0 IL 164358A0 IL 16435803 A IL16435803 A IL 16435803A IL 16435803 A IL16435803 A IL 16435803A IL 164358 A0 IL164358 A0 IL 164358A0
Authority
IL
Israel
Prior art keywords
superantigen
broad
spectrum
interaction
antagonists based
Prior art date
Application number
IL16435803A
Original Assignee
Yissum Res Dev Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yissum Res Dev Co filed Critical Yissum Res Dev Co
Priority to IL16435803A priority Critical patent/IL164358A0/en
Publication of IL164358A0 publication Critical patent/IL164358A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70521—CD28, CD152
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
IL16435803A 2002-04-04 2003-04-03 Broad-spectrum in-vivo effective superantigen toxin antagonists based on the interaction between cd28 and the superantigen and uses thereof IL164358A0 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IL16435803A IL164358A0 (en) 2002-04-04 2003-04-03 Broad-spectrum in-vivo effective superantigen toxin antagonists based on the interaction between cd28 and the superantigen and uses thereof

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IL14899302A IL148993A0 (en) 2002-04-04 2002-04-04 Broad-spectrum in-vivo effective superantigen toxin antagonists based on the interaction between cd28 and the superantigen and uses thereof
PCT/IL2003/000278 WO2003084995A2 (en) 2002-04-04 2003-04-03 Broad-spectrum in-vivo effective superantigen toxin antagonists based on the interaction between cd28 and the superantigen and uses thereof
IL16435803A IL164358A0 (en) 2002-04-04 2003-04-03 Broad-spectrum in-vivo effective superantigen toxin antagonists based on the interaction between cd28 and the superantigen and uses thereof

Publications (1)

Publication Number Publication Date
IL164358A0 true IL164358A0 (en) 2005-12-18

Family

ID=28460340

Family Applications (3)

Application Number Title Priority Date Filing Date
IL14899302A IL148993A0 (en) 2002-04-04 2002-04-04 Broad-spectrum in-vivo effective superantigen toxin antagonists based on the interaction between cd28 and the superantigen and uses thereof
IL16435803A IL164358A0 (en) 2002-04-04 2003-04-03 Broad-spectrum in-vivo effective superantigen toxin antagonists based on the interaction between cd28 and the superantigen and uses thereof
IL164358A IL164358A (en) 2002-04-04 2004-09-28 Superantigen binding site within the cd28 molucule, peptides derived therefrom and uses thereof

Family Applications Before (1)

Application Number Title Priority Date Filing Date
IL14899302A IL148993A0 (en) 2002-04-04 2002-04-04 Broad-spectrum in-vivo effective superantigen toxin antagonists based on the interaction between cd28 and the superantigen and uses thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL164358A IL164358A (en) 2002-04-04 2004-09-28 Superantigen binding site within the cd28 molucule, peptides derived therefrom and uses thereof

Country Status (6)

Country Link
EP (1) EP1492808A2 (en)
JP (2) JP4624684B2 (en)
AU (1) AU2003219489B2 (en)
CA (1) CA2480598A1 (en)
IL (3) IL148993A0 (en)
WO (1) WO2003084995A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL148993A0 (en) * 2002-04-04 2002-11-10 Yissum Res Dev Co Broad-spectrum in-vivo effective superantigen toxin antagonists based on the interaction between cd28 and the superantigen and uses thereof
US8535672B2 (en) 2002-04-04 2013-09-17 Yissum Research Development Of The Hebrew University Of Jerusalem Broad-spectrum in-vivo effective superantigen toxin antagonists based on the interaction between CD28 and the superantigen and uses thereof
AU2003272065A1 (en) 2003-04-03 2004-10-25 Yissum Research Development Company Of The Hebrew University Of Jerusalem Broad-spectrum in-vivo effective superantigen toxin antagonists based on the interaction between cd28 and the superantigen and uses thereof
TWI686405B (en) 2008-12-09 2020-03-01 建南德克公司 Anti-pd-l1 antibodies and their use to enhance t-cell function

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6060054A (en) * 1996-04-10 2000-05-09 National Jewish Medical And Research Center Product for T lymphocyte immunosuppression
IL119938A (en) * 1996-12-30 2005-08-31 Yissum Res Dev Co Peptides capable of eliciting protective immunity against toxic shock induced by pyrogenic exotoxins or of antagonizing toxin-mediated activation of t cells
WO1998056401A1 (en) * 1997-06-12 1998-12-17 Applied Research Systems Ars Holding N.V. Cd28/ctla-4 inhibiting peptidomimetics, pharmaceutical compositions thereof, and method of using same
IL148993A0 (en) * 2002-04-04 2002-11-10 Yissum Res Dev Co Broad-spectrum in-vivo effective superantigen toxin antagonists based on the interaction between cd28 and the superantigen and uses thereof
AU2003272065A1 (en) * 2003-04-03 2004-10-25 Yissum Research Development Company Of The Hebrew University Of Jerusalem Broad-spectrum in-vivo effective superantigen toxin antagonists based on the interaction between cd28 and the superantigen and uses thereof

Also Published As

Publication number Publication date
EP1492808A2 (en) 2005-01-05
CA2480598A1 (en) 2003-10-16
JP2006505500A (en) 2006-02-16
IL148993A0 (en) 2002-11-10
AU2003219489B2 (en) 2010-04-15
JP4624684B2 (en) 2011-02-02
AU2003219489A1 (en) 2003-10-20
JP2010195797A (en) 2010-09-09
WO2003084995A2 (en) 2003-10-16
IL164358A (en) 2013-02-28
WO2003084995A3 (en) 2003-12-18

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