IL162462A0 - Intracellular generation of single-stranded dna - Google Patents
Intracellular generation of single-stranded dnaInfo
- Publication number
- IL162462A0 IL162462A0 IL16246202A IL16246202A IL162462A0 IL 162462 A0 IL162462 A0 IL 162462A0 IL 16246202 A IL16246202 A IL 16246202A IL 16246202 A IL16246202 A IL 16246202A IL 162462 A0 IL162462 A0 IL 162462A0
- Authority
- IL
- Israel
- Prior art keywords
- stranded dna
- intracellular generation
- intracellular
- generation
- stranded
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/102—Mutagenizing nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/11—Antisense
- C12N2310/111—Antisense spanning the whole gene, or a large part of it
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/15—Nucleic acids forming more than 2 strands, e.g. TFOs
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US34080301P | 2001-12-14 | 2001-12-14 | |
| PCT/US2002/040024 WO2003052071A2 (en) | 2001-12-14 | 2002-12-13 | Intracellular generation of single-stranded dna |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL162462A0 true IL162462A0 (en) | 2005-11-20 |
Family
ID=23335000
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL16246202A IL162462A0 (en) | 2001-12-14 | 2002-12-13 | Intracellular generation of single-stranded dna |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20030148352A1 (en) |
| EP (1) | EP1468086A2 (en) |
| CN (1) | CN1620503A (en) |
| AU (1) | AU2002363997A1 (en) |
| CA (1) | CA2470033A1 (en) |
| IL (1) | IL162462A0 (en) |
| MX (1) | MXPA04005747A (en) |
| WO (1) | WO2003052071A2 (en) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050020526A1 (en) * | 2003-06-03 | 2005-01-27 | Cytogenix, Inc. | Oligodeoxynucleotide intervention for prevention and treatment of sepsis |
| US20040248101A1 (en) * | 2003-06-03 | 2004-12-09 | Cytogenix, Inc. | Identification of novel antibacteria agents by screening the single-stranded DNA expression library |
| EP1773995B1 (en) * | 2004-08-03 | 2009-10-07 | The Regents Of The University Of California | Site specific system for generating diversity protein sequences |
| WO2015172149A1 (en) | 2014-05-09 | 2015-11-12 | Yale University | Hyperbranched polyglycerol-coated particles and methods of making and using thereof |
| US11918695B2 (en) | 2014-05-09 | 2024-03-05 | Yale University | Topical formulation of hyperbranched polymer-coated particles |
| CN109476706A (en) * | 2016-02-16 | 2019-03-15 | 耶鲁大学 | For promoting the composition and its application method of target gene editor |
| WO2017143061A1 (en) | 2016-02-16 | 2017-08-24 | Yale University | Compositions and methods for treatment of cystic fibrosis |
| WO2018187493A1 (en) | 2017-04-04 | 2018-10-11 | Yale University | Compositions and methods for in utero delivery |
| US20210189431A1 (en) | 2018-08-10 | 2021-06-24 | Yale University | Compositions and methods for embryonic gene editing in vitro |
| CN112912502A (en) | 2018-08-31 | 2021-06-04 | 耶鲁大学 | Compositions and methods for enhancing triplex and nuclease-based gene editing |
| WO2020112195A1 (en) | 2018-11-30 | 2020-06-04 | Yale University | Compositions, technologies and methods of using plerixafor to enhance gene editing |
| US20220243211A1 (en) | 2019-06-21 | 2022-08-04 | Yale University | Peptide nucleic acid compositions with modified hoogsteen binding segments and methods of use thereof |
| WO2020257779A1 (en) | 2019-06-21 | 2020-12-24 | Yale University | Hydroxymethyl-modified gamma-pna compositions and methods of use thereof |
| US20220339294A1 (en) | 2019-09-09 | 2022-10-27 | Yale University | Nanoparticles for selective tissue or cellular uptake |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5792632A (en) * | 1992-05-05 | 1998-08-11 | Institut Pasteur | Nucleotide sequence encoding the enzyme I-SceI and the uses thereof |
| US5962426A (en) * | 1993-06-25 | 1999-10-05 | Yale University | Triple-helix forming oligonucleotides for targeted mutagenesis |
| AU6430599A (en) * | 1998-10-09 | 2000-05-01 | Cytogenix, Inc. | Enzymatic synthesis of ssdna |
| CA2345936A1 (en) * | 1998-10-09 | 2000-04-20 | Ingene, Inc. | Production of ssdna in a cell |
| IL148946A0 (en) * | 1999-10-04 | 2002-09-12 | Cytogenix Inc | Altering gene expression with ssdna produced in vivo |
-
2002
- 2002-12-13 US US10/319,369 patent/US20030148352A1/en not_active Abandoned
- 2002-12-13 CN CN02828039.3A patent/CN1620503A/en active Pending
- 2002-12-13 CA CA002470033A patent/CA2470033A1/en not_active Abandoned
- 2002-12-13 IL IL16246202A patent/IL162462A0/en unknown
- 2002-12-13 WO PCT/US2002/040024 patent/WO2003052071A2/en not_active Application Discontinuation
- 2002-12-13 AU AU2002363997A patent/AU2002363997A1/en not_active Abandoned
- 2002-12-13 MX MXPA04005747A patent/MXPA04005747A/en not_active Application Discontinuation
- 2002-12-13 EP EP02798516A patent/EP1468086A2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP1468086A2 (en) | 2004-10-20 |
| CA2470033A1 (en) | 2003-06-26 |
| AU2002363997A1 (en) | 2003-06-30 |
| WO2003052071A2 (en) | 2003-06-26 |
| US20030148352A1 (en) | 2003-08-07 |
| WO2003052071A3 (en) | 2003-11-20 |
| MXPA04005747A (en) | 2005-07-05 |
| CN1620503A (en) | 2005-05-25 |
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