IL160938A - Coniosulphides and their derivatives, processes for preparing them and their use as pharmaceuticals - Google Patents

Coniosulphides and their derivatives, processes for preparing them and their use as pharmaceuticals

Info

Publication number
IL160938A
IL160938A IL160938A IL16093804A IL160938A IL 160938 A IL160938 A IL 160938A IL 160938 A IL160938 A IL 160938A IL 16093804 A IL16093804 A IL 16093804A IL 160938 A IL160938 A IL 160938A
Authority
IL
Israel
Prior art keywords
coniosulphides
pharmaceuticals
derivatives
preparing
processes
Prior art date
Application number
IL160938A
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Publication of IL160938A publication Critical patent/IL160938A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/44—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P11/00—Preparation of sulfur-containing organic compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/001—Amines; Imines
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
IL160938A 2001-09-22 2004-03-18 Coniosulphides and their derivatives, processes for preparing them and their use as pharmaceuticals IL160938A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10146737A DE10146737A1 (en) 2001-09-22 2001-09-22 Coniosulfides and their derivatives, process for their preparation and use as medicines
PCT/EP2002/009977 WO2003029495A2 (en) 2001-09-22 2002-09-06 Coniosulphides and their derivatives, method for their production and use as medicaments

Publications (1)

Publication Number Publication Date
IL160938A true IL160938A (en) 2010-11-30

Family

ID=7699903

Family Applications (2)

Application Number Title Priority Date Filing Date
IL16093802A IL160938A0 (en) 2001-09-22 2002-09-06 Coniosulphides and their derivatives, processes for preparing them, and their use as pharmaceuticals
IL160938A IL160938A (en) 2001-09-22 2004-03-18 Coniosulphides and their derivatives, processes for preparing them and their use as pharmaceuticals

Family Applications Before (1)

Application Number Title Priority Date Filing Date
IL16093802A IL160938A0 (en) 2001-09-22 2002-09-06 Coniosulphides and their derivatives, processes for preparing them, and their use as pharmaceuticals

Country Status (12)

Country Link
EP (2) EP1474440B1 (en)
JP (2) JP4287744B2 (en)
AR (1) AR036554A1 (en)
AT (2) ATE430131T1 (en)
AU (1) AU2002339519B2 (en)
CA (1) CA2461033C (en)
DE (3) DE10146737A1 (en)
ES (2) ES2314107T3 (en)
IL (2) IL160938A0 (en)
MX (1) MXPA04001951A (en)
PE (1) PE20030466A1 (en)
WO (1) WO2003029495A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3330252B1 (en) * 2008-11-11 2020-02-12 Signum Biosciences, Inc. Isoprenyl compounds and methods thereof
WO2019198825A1 (en) * 2018-04-13 2019-10-17 国立大学法人京都大学 Prophylactic, therapeutic, or diagnostic drug for alzheimer's disease using microorganism-derived compound

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9210393D0 (en) * 1992-05-15 1992-07-01 Merck Sharp & Dohme Therapeutic agents
FR2740454B1 (en) * 1995-10-26 1997-11-21 Rhone Poulenc Rorer Sa PEPTIDES CAPABLE OF INHIBITING APP ENDOCYTOSIS AND CORRESPONDING NUCLEOTIDE SEQUENCES
WO1998021327A1 (en) 1996-11-08 1998-05-22 Rhone-Poulenc Rorer S.A. Peptides capable of inhibiting the endocytosis of the app and corresponding nucleotide sequences
NZ520697A (en) * 2000-02-10 2005-11-25 Aventis Pharma Sa Partners of PTB1 domain of FE65, preparation and uses
DE10060810A1 (en) 2000-12-07 2002-06-20 Aventis Pharma Gmbh Coniosetin and derivatives thereof, processes for making and using the same

Also Published As

Publication number Publication date
DE50212774D1 (en) 2008-10-23
MXPA04001951A (en) 2004-06-07
EP1903033A1 (en) 2008-03-26
ES2326563T3 (en) 2009-10-14
EP1474440B1 (en) 2008-09-10
WO2003029495A3 (en) 2004-02-26
DE50213512D1 (en) 2009-06-10
JP4287744B2 (en) 2009-07-01
JP2005504131A (en) 2005-02-10
CA2461033C (en) 2011-12-06
ATE407942T1 (en) 2008-09-15
ATE430131T1 (en) 2009-05-15
IL160938A0 (en) 2004-08-31
EP1474440A2 (en) 2004-11-10
WO2003029495A2 (en) 2003-04-10
PE20030466A1 (en) 2003-07-08
DE10146737A1 (en) 2003-04-10
AU2002339519B2 (en) 2007-02-08
ES2314107T3 (en) 2009-03-16
AR036554A1 (en) 2004-09-15
JP2009149662A (en) 2009-07-09
CA2461033A1 (en) 2003-04-10
EP1903033B1 (en) 2009-04-29

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Legal Events

Date Code Title Description
FF Patent granted
MM9K Patent not in force due to non-payment of renewal fees