IL155784A0 - PROCESS FOR THE ENZYMATIC PREPARATION OF ENANTIOMER-ENRICHED beta-AMINO ACIDS - Google Patents

PROCESS FOR THE ENZYMATIC PREPARATION OF ENANTIOMER-ENRICHED beta-AMINO ACIDS

Info

Publication number
IL155784A0
IL155784A0 IL15578403A IL15578403A IL155784A0 IL 155784 A0 IL155784 A0 IL 155784A0 IL 15578403 A IL15578403 A IL 15578403A IL 15578403 A IL15578403 A IL 15578403A IL 155784 A0 IL155784 A0 IL 155784A0
Authority
IL
Israel
Prior art keywords
enantiomer
amino acids
enzymatic preparation
beta
enriched beta
Prior art date
Application number
IL15578403A
Other versions
IL155784A (en
Original Assignee
Degussa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Degussa filed Critical Degussa
Publication of IL155784A0 publication Critical patent/IL155784A0/en
Publication of IL155784A publication Critical patent/IL155784A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/005—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of carboxylic acid groups in the enantiomers or the inverse reaction
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

A process for the production of enantiomer enriched N-unprotected, preferably open chain beta-aminoacids comprises enzymatic hydrolysis of an enantiomer mixture of corresponding beta-aminoacid esters with a hydrolase, whereby the hydrolysis is carried out in a two-phase system of water and an organic solvent that forms a second phase under the reaction conditions.
IL155784A 2002-05-08 2003-05-06 Process for the enzymatic preparation of enantiomer-enriched amino acids IL155784A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10220740A DE10220740A1 (en) 2002-05-08 2002-05-08 Production of enantiomer enriched N-unprotected beta-aminoacids, useful for production of pharmaceuticals, comprises enzymatic hydrolysis of beta-aminoacid esters with hydrolase in two-phase system of water and organic solvent

Publications (2)

Publication Number Publication Date
IL155784A0 true IL155784A0 (en) 2003-12-23
IL155784A IL155784A (en) 2010-06-30

Family

ID=29285247

Family Applications (1)

Application Number Title Priority Date Filing Date
IL155784A IL155784A (en) 2002-05-08 2003-05-06 Process for the enzymatic preparation of enantiomer-enriched amino acids

Country Status (10)

Country Link
EP (1) EP1367129B1 (en)
JP (1) JP4662694B2 (en)
KR (1) KR101043190B1 (en)
CN (1) CN1327002C (en)
AT (1) ATE435299T1 (en)
CA (1) CA2428163C (en)
DE (2) DE10220740A1 (en)
HR (1) HRP20030356A2 (en)
IL (1) IL155784A (en)
SG (1) SG120092A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2853327B1 (en) * 2003-04-04 2012-07-27 Solvay PROCESS FOR THE PRODUCTION OF ENANTIOPOR BETA-AMINOACID DERIVATIVES AND ENANTIOPA BETA-AMINOACIDIC DERIVATIVES
CA2547733C (en) 2003-12-10 2009-09-08 Degussa Ag Process for the preparation of enantiomerically enriched amino acids
CN1926241A (en) * 2004-02-27 2007-03-07 帝斯曼知识产权资产管理有限公司 Enzymatic preparation of an enantiomerically enriched beta-2-amino acids
JP4608938B2 (en) * 2004-05-12 2011-01-12 宇部興産株式会社 Process for producing optically active 3-alkyl-3-arylpropionic acid and optically active 3-alkyl-3-arylpropionic acid alkyl ester
JP4608963B2 (en) * 2004-06-22 2011-01-12 宇部興産株式会社 Process for producing optically active 3-aryl-3-hydroxypropionic acid and optically active 3-aryl-3-hydroxypropionic acid alkyl ester
ES2359253T3 (en) * 2004-10-08 2011-05-19 Ube Industries, Ltd. PROCEDURE FOR THE PRODUCTION OF (S) - O (R) -BETA-OPTICALLY ACTIVE AND ESTERES AMINO ACIDS OF (R) - O (S) -BETA-OPTIMALLY ACTIVE AMINO ACIDS, AND (S) - O (R) -2-ALCOXIETIL OPTICALLY ACTIVE BETA-AMINO ACIDS ESTERS.
DE102004057966A1 (en) * 2004-11-30 2006-06-01 Degussa Ag Method for asymmetrical enzymatic production of optically active organic compounds in microemulsion
EP1887086A4 (en) * 2005-05-17 2010-10-27 Ube Industries Process for production of carboxylic acid using surfactant-modifying enzyme

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2927535A1 (en) * 1979-07-07 1981-01-08 Bayer Ag STEREOSELECTIVE CUTTING OF PHENYLGLYCINE DERIVATIVES WITH ENZYME RESINS
US4636470A (en) * 1984-08-17 1987-01-13 Stauffer Chemical Company Resolution of racemates of amino acids

Also Published As

Publication number Publication date
KR20030087562A (en) 2003-11-14
KR101043190B1 (en) 2011-06-22
SG120092A1 (en) 2006-03-28
CN1456676A (en) 2003-11-19
IL155784A (en) 2010-06-30
DE10220740A1 (en) 2003-11-27
EP1367129A3 (en) 2003-12-17
DE50311645D1 (en) 2009-08-13
ATE435299T1 (en) 2009-07-15
CA2428163A1 (en) 2003-11-08
CN1327002C (en) 2007-07-18
CA2428163C (en) 2011-08-09
JP4662694B2 (en) 2011-03-30
EP1367129B1 (en) 2009-07-01
JP2003325197A (en) 2003-11-18
HRP20030356A2 (en) 2004-04-30
EP1367129A2 (en) 2003-12-03

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