IL155561A0 - Oligonucleotides that block toll-like receptors - Google Patents

Oligonucleotides that block toll-like receptors

Info

Publication number
IL155561A0
IL155561A0 IL155561A IL15556103A IL155561A0 IL 155561 A0 IL155561 A0 IL 155561A0 IL 155561 A IL155561 A IL 155561A IL 15556103 A IL15556103 A IL 15556103A IL 155561 A0 IL155561 A0 IL 155561A0
Authority
IL
Israel
Prior art keywords
oligonucleotides
receptors
toll
block
block toll
Prior art date
Application number
IL155561A
Original Assignee
Yeda Res & Dev
Irun Cohen
Gabriel Nussbaum
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Res & Dev, Irun Cohen, Gabriel Nussbaum filed Critical Yeda Res & Dev
Priority to IL155561A priority Critical patent/IL155561A0/en
Priority to PCT/IL2004/000349 priority patent/WO2004093778A2/en
Publication of IL155561A0 publication Critical patent/IL155561A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/11—Antisense
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/11—Antisense
    • C12N2310/111—Antisense spanning the whole gene, or a large part of it
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/14—Type of nucleic acid interfering N.A.
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/31—Chemical structure of the backbone
    • C12N2310/315—Phosphorothioates

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL155561A 2003-04-24 2003-04-24 Oligonucleotides that block toll-like receptors IL155561A0 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
IL155561A IL155561A0 (en) 2003-04-24 2003-04-24 Oligonucleotides that block toll-like receptors
PCT/IL2004/000349 WO2004093778A2 (en) 2003-04-24 2004-04-25 Oligonucleotides that block toll-like receptors

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL155561A IL155561A0 (en) 2003-04-24 2003-04-24 Oligonucleotides that block toll-like receptors

Publications (1)

Publication Number Publication Date
IL155561A0 true IL155561A0 (en) 2006-12-31

Family

ID=33307093

Family Applications (1)

Application Number Title Priority Date Filing Date
IL155561A IL155561A0 (en) 2003-04-24 2003-04-24 Oligonucleotides that block toll-like receptors

Country Status (2)

Country Link
IL (1) IL155561A0 (en)
WO (1) WO2004093778A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005052192A1 (en) * 2003-11-21 2005-06-09 University Of Massachusetts Pancreatitis
JP2007534775A (en) 2004-05-28 2007-11-29 セダーズ−シナイ メディカル センター Methods for treating vascular disease
US7629135B2 (en) 2006-12-22 2009-12-08 The Board Of Trustees Of The University Of Illinois Toll-like receptor agonists and antagonists and methods of use thereof
US9512196B2 (en) 2008-09-22 2016-12-06 Cedars-Sinai Medical Center Short-form human MD-2 as a negative regulator of toll-like receptor 4 signaling
EP2328911A4 (en) 2008-09-22 2012-03-14 Cedars Sinai Medical Center Short-form human md-2 as a negative regulator of toll-like receptor 4 signaling
US9796979B2 (en) 2011-03-03 2017-10-24 Quark Pharmaceuticals Inc. Oligonucleotide modulators of the toll-like receptor pathway
SG193280A1 (en) 2011-03-03 2013-10-30 Quark Pharmaceuticals Inc Oligonucleotide modulators of the toll-like receptor pathway

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6506559B1 (en) * 1997-12-23 2003-01-14 Carnegie Institute Of Washington Genetic inhibition by double-stranded RNA
US6740487B1 (en) * 1999-06-10 2004-05-25 University Of Iowa Research Foundation Variant TLR4 nucleic acid and uses thereof

Also Published As

Publication number Publication date
WO2004093778A2 (en) 2004-11-04
WO2004093778A8 (en) 2005-05-19
WO2004093778A3 (en) 2007-05-03

Similar Documents

Publication Publication Date Title
HK1071970A1 (en) Network device
EP1620544A4 (en) MODIFIED iRNA AGENTS
AU155540S (en) Dispenser
AU153556S (en) Dispenser
AU158090S (en) Dispenser
GB2422335A8 (en) Biochip
GB0310841D0 (en) Block
GB0416577D0 (en) Improved lubricant dispensers
AU153757S (en) Dispenser
GB0323043D0 (en) Biochip
IL155561A0 (en) Oligonucleotides that block toll-like receptors
IL173337A0 (en) Receptor
AU155406S (en) Dispenser
EP1694640A4 (en) Anti-cancer agents
AU155539S (en) Dispenser
GB2408703B8 (en) Dispensers
EP1610493A4 (en) Network design device
AU156500S (en) Dispenser
IL149343A0 (en) Antisense oligonucleotides that block toll-like receptors
GB0322774D0 (en) Extension device
EP1593416A4 (en) Block
AU153555S (en) Dispenser
GB0321998D0 (en) Receptor
GB0304065D0 (en) Receptors
GB0304090D0 (en) Receptors