IL153864A0 - Cyclic polyamine compounds and methods for the preparation thereof - Google Patents

Cyclic polyamine compounds and methods for the preparation thereof

Info

Publication number
IL153864A0
IL153864A0 IL15386401A IL15386401A IL153864A0 IL 153864 A0 IL153864 A0 IL 153864A0 IL 15386401 A IL15386401 A IL 15386401A IL 15386401 A IL15386401 A IL 15386401A IL 153864 A0 IL153864 A0 IL 153864A0
Authority
IL
Israel
Prior art keywords
preparation
methods
polyamine compounds
cyclic polyamine
cyclic
Prior art date
Application number
IL15386401A
Original Assignee
Slil Biomedical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Slil Biomedical Corp filed Critical Slil Biomedical Corp
Publication of IL153864A0 publication Critical patent/IL153864A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D255/00—Heterocyclic compounds containing rings having three nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D249/00 - C07D253/00
    • C07D255/02—Heterocyclic compounds containing rings having three nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D249/00 - C07D253/00 not condensed with other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL15386401A 2000-08-02 2001-08-02 Cyclic polyamine compounds and methods for the preparation thereof IL153864A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22252200P 2000-08-02 2000-08-02
PCT/US2001/024282 WO2002010142A1 (en) 2000-08-02 2001-08-02 Cyclic polyamine compounds for cancer therapy

Publications (1)

Publication Number Publication Date
IL153864A0 true IL153864A0 (en) 2003-07-31

Family

ID=22832553

Family Applications (1)

Application Number Title Priority Date Filing Date
IL15386401A IL153864A0 (en) 2000-08-02 2001-08-02 Cyclic polyamine compounds and methods for the preparation thereof

Country Status (7)

Country Link
EP (1) EP1305299A1 (en)
JP (1) JP2004505112A (en)
AU (2) AU2001278143B2 (en)
CA (1) CA2417064A1 (en)
IL (1) IL153864A0 (en)
MX (1) MXPA03000905A (en)
WO (1) WO2002010142A1 (en)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005533820A (en) * 2002-06-26 2005-11-10 セルゲイト， インコーポレイテッド Porphyrin-polyamine conjugates for cancer treatment
EP1940773B1 (en) 2005-08-10 2015-03-18 Johns Hopkins University Polyamines useful as anti-parasitic and anti-cancer therapeutics and as lysine-specific demethylase inhibitors
US9822364B2 (en) 2008-03-11 2017-11-21 Yale University Compositions and methods for controlled delivery of inhibitory ribonucleic acids
US9241898B2 (en) 2008-03-11 2016-01-26 Yale University Compositions and methods for controlled delivery of inhibitory ribonucleic acids
WO2013082529A1 (en) 2011-12-02 2013-06-06 Yale University Enzymatic synthesis of poly(amine-co-esters) and methods of use thereof for gene delivery
US10465042B2 (en) 2011-12-02 2019-11-05 Yale University Poly(amine-co-ester) nanoparticles and methods of use thereof
US9895451B2 (en) 2011-12-02 2018-02-20 Yale University Formulations for targeted release of agents to low pH tissue environments or cellular compartments and methods of use thereof
EP2822936B1 (en) 2012-03-07 2021-09-08 The McLean Hospital Corporation Aminoquinoline derivatives and uses thereof
JP2015524078A (en) * 2012-05-15 2015-08-20 サーモ エレクトロン サイエンティフィック インストルメンツ リミテッド ライアビリティ カンパニー Ultra-wideband multilayer dielectric beam splitter film
EP4331618A3 (en) 2014-05-09 2024-06-12 Yale University Hyperbranched polyglycerol-coated particles and methods of making and using thereof
US11918695B2 (en) 2014-05-09 2024-03-05 Yale University Topical formulation of hyperbranched polymer-coated particles
US10815276B2 (en) 2014-05-21 2020-10-27 Entrada Therapeutics, Inc. Cell penetrating peptides and methods of making and using thereof
HUE045872T2 (en) 2014-05-21 2020-01-28 Entrada Therapeutics Inc Cell penetrating peptides and methods of making and using thereof
EP3185880B1 (en) 2014-08-27 2020-02-12 Ohio State Innovation Foundation Improved peptidyl calcineurin inhibitors
US10682422B2 (en) 2014-11-18 2020-06-16 Yale University Formulations for targeted release of agents under low pH conditions and methods of use thereof
WO2016081621A1 (en) 2014-11-18 2016-05-26 Yale University Formulations for targeted release of agents under low ph conditions and methods of use thereof
WO2017143042A2 (en) 2016-02-16 2017-08-24 Yale University Compositions for enhancing targeted gene editing and methods of use thereof
AU2017221424A1 (en) 2016-02-16 2018-09-20 Yale University Compositions and methods for treatment of cystic fibrosis
WO2017197128A1 (en) 2016-05-11 2017-11-16 Yale University Poly(amine-co-ester) nanoparticles and methods of use thereof
WO2018187493A1 (en) 2017-04-04 2018-10-11 Yale University Compositions and methods for in utero delivery
US11576946B2 (en) 2018-01-29 2023-02-14 Ohio State Innovation Foundation Peptidyl inhibitors of calcineurin-NFAT interaction
TW201945014A (en) 2018-02-22 2019-12-01 美商安卓達治療股份有限公司 Compositions and methods for treating Mitochondrial Neurogastrointestinal Encephalopathy
WO2019217682A1 (en) 2018-05-09 2019-11-14 Ohio State Innovation Foundation Cyclic cell-penetrating peptides with one or more hydrophobic residues
WO2020033951A1 (en) 2018-08-10 2020-02-13 Yale University Compositions and methods for embryonic gene editing in vitro
US11814464B2 (en) 2019-04-29 2023-11-14 Yale University Poly(amine-co-ester) polymers and polyplexes with modified end groups and methods of use thereof
US20220243211A1 (en) 2019-06-21 2022-08-04 Yale University Peptide nucleic acid compositions with modified hoogsteen binding segments and methods of use thereof
US20220372474A1 (en) 2019-06-21 2022-11-24 Yale University Hydroxymethyl-modified gamma-pna compositions and methods of use thereof
WO2021022161A1 (en) 2019-07-31 2021-02-04 Yale University Compositions and methods for treating sickle cell disease
MX2022016581A (en) 2020-06-19 2023-02-01 Univ Yale Poly(amine-co-ester) polymers with modified end groups and enhanced pulmonary delivery.
US20220031633A1 (en) 2020-07-28 2022-02-03 Yale University Poly(amine-co-ester) polymeric particles for selective pulmonary delivery
US20230172870A1 (en) 2021-12-08 2023-06-08 Yale University Surface conjugation to poly(amine-co-ester) nanoparticles for targeting to cells and tissues
WO2023159189A1 (en) 2022-02-18 2023-08-24 Yale University Branched poly(amine-co-ester) polymers for more efficient nucleic expression
CN117088825A (en) * 2023-10-12 2023-11-21 成都威斯津生物医药科技有限公司 Ionizable lipid, pharmaceutical composition containing same and application thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4999349A (en) * 1990-03-22 1991-03-12 Bristol-Myers Squibb Co. BU-4164E - A and B, prolyl endopeptidase inhibitors
EP0792875B1 (en) * 1996-02-27 2001-05-09 Eli Lilly And Company Cryptophycin derivatives and their use as anti-microtubule agents

Also Published As

Publication number Publication date
MXPA03000905A (en) 2003-06-24
EP1305299A1 (en) 2003-05-02
AU7814301A (en) 2002-02-13
WO2002010142A1 (en) 2002-02-07
AU2001278143B2 (en) 2007-08-09
CA2417064A1 (en) 2002-02-07
JP2004505112A (en) 2004-02-19

Similar Documents

Publication Publication Date Title
IL153864A0 (en) Cyclic polyamine compounds and methods for the preparation thereof
HK1052183A1 (en) Method for the preparation of tetrahydrobenzothiepines
IL150908A0 (en) Single phase gels and methods for the preparation thereof
AU6275601A (en) Stable polymeric micelle-type drug composition and method for the preparation thereof
AU4114201A (en) Cyclic compounds
GB0008264D0 (en) Novel method and compounds
AU4433702A (en) Vaccines
GB0024200D0 (en) Component vaccine
AU1591402A (en) Vaccine
IL155177A0 (en) Method for the preparation of grf-peg conjugate
EP1434772A4 (en) Compounds and methods
IL153505A0 (en) Dds compound and process for the preparation thereof
AU2002359694A8 (en) Compounds and methods
TW426082U (en) Locking device
GB0026094D0 (en) Methods
EP1379240A4 (en) Compounds and methods
GB0001005D0 (en) Methods
GB2369345B (en) Locking device
GB0003082D0 (en) Vaccine
GB0027433D0 (en) Vaccine component
GB0102454D0 (en) Methods
GB0024510D0 (en) Methods
GB0004533D0 (en) Vaccines
EP1338275A4 (en) Pharmaceutical composition, the use thereof and method for producing said composition
AU7035601A (en) Novel compounds and methods