IL151375A0 - Nucleic acid molecule containing a neuregulin-1-associated gene and polypeptides encoded thereby - Google Patents

Nucleic acid molecule containing a neuregulin-1-associated gene and polypeptides encoded thereby

Info

Publication number
IL151375A0
IL151375A0 IL15137501A IL15137501A IL151375A0 IL 151375 A0 IL151375 A0 IL 151375A0 IL 15137501 A IL15137501 A IL 15137501A IL 15137501 A IL15137501 A IL 15137501A IL 151375 A0 IL151375 A0 IL 151375A0
Authority
IL
Israel
Prior art keywords
neuregulin
nucleic acid
acid molecule
molecule containing
polypeptides encoded
Prior art date
Application number
IL15137501A
Other languages
English (en)
Original Assignee
Decode Genetics Ehf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Decode Genetics Ehf filed Critical Decode Genetics Ehf
Publication of IL151375A0 publication Critical patent/IL151375A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/4756Neuregulins, i.e. p185erbB2 ligands, glial growth factor, heregulin, ARIA, neu differentiation factor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Neurosurgery (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL15137501A 2000-02-28 2001-02-28 Nucleic acid molecule containing a neuregulin-1-associated gene and polypeptides encoded thereby IL151375A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51571500A 2000-02-28 2000-02-28
PCT/US2001/006376 WO2001064876A2 (en) 2000-02-28 2001-02-28 Human schizophrenia gene

Publications (1)

Publication Number Publication Date
IL151375A0 true IL151375A0 (en) 2003-04-10

Family

ID=24052437

Family Applications (1)

Application Number Title Priority Date Filing Date
IL15137501A IL151375A0 (en) 2000-02-28 2001-02-28 Nucleic acid molecule containing a neuregulin-1-associated gene and polypeptides encoded thereby

Country Status (9)

Country Link
US (1) US20020094954A1 (xx)
EP (1) EP1259609A2 (xx)
JP (1) JP2004527203A (xx)
KR (1) KR20030072205A (xx)
AU (1) AU2001241838A1 (xx)
CA (1) CA2400679A1 (xx)
IL (1) IL151375A0 (xx)
MX (1) MXPA02008238A (xx)
WO (1) WO2001064876A2 (xx)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6528640B1 (en) * 1997-11-05 2003-03-04 Ribozyme Pharmaceuticals, Incorporated Synthetic ribonucleic acids with RNAse activity
US6482932B1 (en) * 1997-11-05 2002-11-19 Ribozyme Pharmaceuticals, Incorporated Nucleoside triphosphates and their incorporation into oligonucleotides
US6617438B1 (en) * 1997-11-05 2003-09-09 Sirna Therapeutics, Inc. Oligoribonucleotides with enzymatic activity
US7495147B2 (en) 2000-02-28 2009-02-24 Decode Genetics Ehf. Neuregulin-1 transgenic mouse and methods of use
WO2003099320A1 (en) 2002-05-24 2003-12-04 Zensun (Shanghai) Sci-Tech.Ltd Neuregulin based methods and compositions for treating viral myocarditis and dilated cardiomyopathy
US20090131308A1 (en) * 2003-08-19 2009-05-21 Agos Biotech Ltd. Splice Variants of ErbB Ligands, Compositions and Uses Thereof
JP2008538238A (ja) * 2005-03-31 2008-10-16 ザ・ボード・オブ・トラスティーズ・オブ・ザ・レランド・スタンフォード・ジュニア・ユニバーシティ 神経精神障害を診断および処置するための組成物および方法
RU2499599C2 (ru) 2007-09-28 2013-11-27 Интрексон Корпорейшн Конструкции терапевтического переключения генов и биореакторы для экспрессии биотерапевтических молекул и их применение
CA2742074A1 (en) * 2008-10-29 2010-08-26 Janssen Pharmaceutica Nv Methods of treating psychosis and schizophrenia based on polymorphisms in the erbb4 gene

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4975960A (en) * 1985-06-03 1990-12-04 Petajan Eric D Electronic facial tracking and detection system and method and apparatus for automated speech recognition
AU7042994A (en) * 1993-05-21 1994-12-20 Amgen, Inc. Recombinant (neu) differentiation factors

Also Published As

Publication number Publication date
CA2400679A1 (en) 2001-09-07
WO2001064876A2 (en) 2001-09-07
AU2001241838A1 (en) 2001-09-12
JP2004527203A (ja) 2004-09-09
WO2001064876A3 (en) 2002-04-18
US20020094954A1 (en) 2002-07-18
MXPA02008238A (es) 2003-09-10
KR20030072205A (ko) 2003-09-13
EP1259609A2 (en) 2002-11-27

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