IL138721A0 - Process for identifying chemical active ingredients and active ingredients for inhibiting the 1-desoxy-d-xylulose-5-phosphate biosynthesis pathway - Google Patents

Process for identifying chemical active ingredients and active ingredients for inhibiting the 1-desoxy-d-xylulose-5-phosphate biosynthesis pathway

Info

Publication number
IL138721A0
IL138721A0 IL13872199A IL13872199A IL138721A0 IL 138721 A0 IL138721 A0 IL 138721A0 IL 13872199 A IL13872199 A IL 13872199A IL 13872199 A IL13872199 A IL 13872199A IL 138721 A0 IL138721 A0 IL 138721A0
Authority
IL
Israel
Prior art keywords
active ingredients
desoxy
xylulose
inhibiting
biosynthesis pathway
Prior art date
Application number
IL13872199A
Original Assignee
Jomaa Hassan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19825585A external-priority patent/DE19825585A1/en
Priority claimed from DE19828097A external-priority patent/DE19828097A1/en
Priority claimed from DE19831639A external-priority patent/DE19831639C1/en
Priority claimed from DE19831637A external-priority patent/DE19831637A1/en
Application filed by Jomaa Hassan filed Critical Jomaa Hassan
Publication of IL138721A0 publication Critical patent/IL138721A0/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N57/00Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds
    • A01N57/18Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06Antimalarials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • C07K14/445Plasmodium
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/527Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving lyase
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Agronomy & Crop Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Dentistry (AREA)
  • Pest Control & Pesticides (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
IL13872199A 1998-04-14 1999-04-13 Process for identifying chemical active ingredients and active ingredients for inhibiting the 1-desoxy-d-xylulose-5-phosphate biosynthesis pathway IL138721A0 (en)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
DE19816196 1998-04-14
DE19825585A DE19825585A1 (en) 1998-04-14 1998-06-09 Treating and preventing viral, fungal or parasitic infections in humans and animals
DE19828097A DE19828097A1 (en) 1998-06-24 1998-06-24 Identifying antiparasitic agents used to treat or prevent parasitic infections, especially malaria, sleeping sickness and leishmaniosis
DE19831638 1998-07-15
DE19831639A DE19831639C1 (en) 1998-07-15 1998-07-15 Identifying antiparasitic agents used to treat or prevent parasitic infections, especially malaria, sleeping sickness and leishmaniosis
DE19831637A DE19831637A1 (en) 1998-07-15 1998-07-15 Identifying antiparasitic agents used to treat or prevent parasitic infections, especially malaria, sleeping sickness and leishmaniosis
DE19843279 1998-09-22
PCT/EP1999/002463 WO1999052938A2 (en) 1998-04-14 1999-04-13 Identification of chemical active agents for inhibiting the 1-desoxy-d-xylulose-5-phosphate biosynthetic pathway in parasites

Publications (1)

Publication Number Publication Date
IL138721A0 true IL138721A0 (en) 2001-10-31

Family

ID=27561757

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13872199A IL138721A0 (en) 1998-04-14 1999-04-13 Process for identifying chemical active ingredients and active ingredients for inhibiting the 1-desoxy-d-xylulose-5-phosphate biosynthesis pathway

Country Status (14)

Country Link
EP (1) EP1071959A2 (en)
JP (1) JP2002511486A (en)
CN (1) CN1297532A (en)
AP (1) AP2000001937A0 (en)
AU (1) AU753169B2 (en)
CA (1) CA2328157A1 (en)
HU (1) HUP0101711A2 (en)
IL (1) IL138721A0 (en)
MX (1) MXPA00010069A (en)
OA (1) OA11500A (en)
PL (1) PL358989A1 (en)
SK (1) SK15232000A3 (en)
TR (1) TR200002972T2 (en)
WO (1) WO1999052938A2 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU757440B2 (en) * 1998-08-05 2003-02-20 Sungene Gmbh And Co. Kgaa DNA sequence coding for a 1-deoxy-d-xylulose-5-phosphate synthase and the overproduction thereof in plants
IL141888A0 (en) * 1998-09-22 2002-03-10 Jomaa Pharmaka Gmbh Genes of the 1-deoxy-d-xylulose biosynthetic pathway
EP1141379A1 (en) * 1998-12-14 2001-10-10 Adelbert Bacher Screening for inhibitors of terpenoids biosynthesis
GB9901902D0 (en) * 1999-01-28 1999-03-17 New Royal Holloway & Bedford Manipulating isoprenoid expression
IL146347A0 (en) * 1999-05-21 2002-07-25 Jomaa Pharmaka Gmbh Use of genes of the deoxy-d-xylulose phosphate biosynthetic pathway for altering the concentration of isoprenoid
US7122331B1 (en) 1999-08-04 2006-10-17 Wolfgang Eisenreich Isoprenoid biosynthesis
DE10021688A1 (en) * 2000-05-05 2001-11-15 Hassan Jomaa New DNA sequences involved in isoprenoid biosynthesis, useful in screening for compounds with e.g. antimicrobial and herbicidal activity
DE10027821A1 (en) * 2000-06-05 2001-12-06 Adelbert Bacher New intermediate in isoprenoid biosynthesis, useful in screening for potential herbicides, comprises mutant encoding-enzymes sequences for imparting herbicide resistance
DE10201458A1 (en) 2001-04-11 2002-10-17 Adelbert Bacher New proteins involved in isoprenoid biosynthesis, useful in screening for inhibitors, also new intermediates, potential therapeutic agents, nucleic acids and antibodies
CN102860999B (en) * 2012-10-12 2014-04-09 西北大学 1-deoxidation-D-xylulose5-phosphoric acid reduction isomerization enzyme inhibitor and preparation method thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19752700A1 (en) * 1997-11-28 1999-06-02 Hoechst Schering Agrevo Gmbh 1-Deoxy-D-xylulose-5-phosphate synthase protein and modulators

Also Published As

Publication number Publication date
OA11500A (en) 2004-05-14
WO1999052938A2 (en) 1999-10-21
JP2002511486A (en) 2002-04-16
MXPA00010069A (en) 2002-08-06
TR200002972T2 (en) 2001-01-22
AU753169B2 (en) 2002-10-10
HUP0101711A2 (en) 2001-09-28
AU4481699A (en) 1999-11-01
SK15232000A3 (en) 2001-05-10
AP2000001937A0 (en) 2000-12-31
EP1071959A2 (en) 2001-01-31
PL358989A1 (en) 2004-08-23
WO1999052938A3 (en) 1999-12-09
CA2328157A1 (en) 1999-10-21
CN1297532A (en) 2001-05-30

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