IL129267A0 - Treatment of urinary incontinence and compositions for use therein - Google Patents
Treatment of urinary incontinence and compositions for use thereinInfo
- Publication number
- IL129267A0 IL129267A0 IL12926797A IL12926797A IL129267A0 IL 129267 A0 IL129267 A0 IL 129267A0 IL 12926797 A IL12926797 A IL 12926797A IL 12926797 A IL12926797 A IL 12926797A IL 129267 A0 IL129267 A0 IL 129267A0
- Authority
- IL
- Israel
- Prior art keywords
- urinary incontinence
- treatment
- compositions
- serotonin
- histamine
- Prior art date
Links
- 206010046543 Urinary incontinence Diseases 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 2
- NTYJJOPFIAHURM-UHFFFAOYSA-N Histamine Chemical compound NCCC1=CN=CN1 NTYJJOPFIAHURM-UHFFFAOYSA-N 0.000 abstract 2
- QZAYGJVTTNCVMB-UHFFFAOYSA-N serotonin Chemical compound C1=C(O)C=C2C(CCN)=CNC2=C1 QZAYGJVTTNCVMB-UHFFFAOYSA-N 0.000 abstract 2
- 229960001340 histamine Drugs 0.000 abstract 1
- 229940076279 serotonin Drugs 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/417—Imidazole-alkylamines, e.g. histamine, phentolamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
Abstract
The present invention relates to a treatment for patients having urinary incontinence by administering a composition comprising histamine, serotonin or a combination thereof in an amount effective to alleviate symptoms of urinary incontinence.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/731,702 US5877198A (en) | 1996-10-17 | 1996-10-17 | Treatment of urinary incontinence |
PCT/US1997/018601 WO1998016225A1 (en) | 1996-10-17 | 1997-10-16 | Treatment of urinary incontinence and compositions for use therein |
Publications (2)
Publication Number | Publication Date |
---|---|
IL129267A0 true IL129267A0 (en) | 2000-02-17 |
IL129267A IL129267A (en) | 2003-10-31 |
Family
ID=24940633
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL12926797A IL129267A (en) | 1996-10-17 | 1997-10-16 | Pharmaceutical compositions comprising histamine and/or serotonin for treatment of urinary incontinence |
Country Status (9)
Country | Link |
---|---|
US (1) | US5877198A (en) |
EP (1) | EP0946174B1 (en) |
JP (1) | JP2001502336A (en) |
AT (1) | ATE271867T1 (en) |
AU (1) | AU729675B2 (en) |
CA (1) | CA2269031C (en) |
DE (1) | DE69730045T2 (en) |
IL (1) | IL129267A (en) |
WO (1) | WO1998016225A1 (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA977967B (en) * | 1996-09-23 | 1999-03-04 | Lilly Co Eli | Combination therapy for treatment of psychoses |
US6156780A (en) * | 1996-10-17 | 2000-12-05 | Milkhaus Laboratory, Inc. | Treatment of fecal incontinence |
WO2014066672A1 (en) * | 2012-10-26 | 2014-05-01 | Beech Tree Labs, Inc. | Method of treating muscular weakness comprising administering a composition comprising an effective amount of histamine and/or serotonin |
AU2018389242A1 (en) | 2017-12-21 | 2020-07-16 | Resolys Bio, Inc. | Compositions and methods of treatment of Ehlers-Danlos Syndromes |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4692332A (en) * | 1985-01-18 | 1987-09-08 | Mcmichael John | Immunotherapeutic methods and compositions employing antigens characteristic of malignant neoplasms |
US4970071A (en) * | 1985-01-18 | 1990-11-13 | Mcmichael John | Immunotherapeutic methods and compositions employing antigens characteristic of non human malignant neoplasms |
US4689222A (en) * | 1985-01-18 | 1987-08-25 | Mcmichael John | Methods and materials for alleviation of pain symptoms of malignant neoplasia |
US4880626A (en) * | 1985-01-18 | 1989-11-14 | Mcmichael John | Immunotherapeutic methods and compositions for the treatment of diseases of viral origin, including acquired immune deficiency syndrome |
US4966753A (en) * | 1987-08-18 | 1990-10-30 | Molecular Rx, Inc. | Immunotherapeutic methods and compositions employing antigens characteristic of malignant neoplasms |
AU2485988A (en) * | 1987-09-10 | 1989-04-17 | John Mcmichael | Method and composition for enhancing animal fertility |
ATE153534T1 (en) * | 1990-04-27 | 1997-06-15 | John Mcmichael | METHOD AND COMPOSITION FOR TREATING CNS DISEASES CAUSED BY ABNORMAL BETA-AMYLOID PROTEIN |
WO1995031996A1 (en) * | 1994-05-25 | 1995-11-30 | Milkhaus Lab | Materials and methods for treatment of plaquing diseases |
FR2732017B1 (en) * | 1995-03-21 | 2000-09-22 | Inst Nat Sante Rech Med | NOVEL IMIDAZOLE DERIVATIVES AND / OR HISTAMINE H3 RECEPTOR AGONISTS AND / OR AGONISTS, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATIONS |
AU716486B2 (en) * | 1995-04-13 | 2000-02-24 | Milkhaus Laboratory, Inc. | Methods for treating respiratory disease |
US5610174A (en) * | 1995-06-02 | 1997-03-11 | Synaptic Pharmaceutical Corporation | Use of α1A -selective adrenoceptor agonists for the treatment of urinary incontinence |
-
1996
- 1996-10-17 US US08/731,702 patent/US5877198A/en not_active Expired - Lifetime
-
1997
- 1997-10-16 IL IL12926797A patent/IL129267A/en not_active IP Right Cessation
- 1997-10-16 DE DE69730045T patent/DE69730045T2/en not_active Expired - Lifetime
- 1997-10-16 AU AU47572/97A patent/AU729675B2/en not_active Ceased
- 1997-10-16 CA CA002269031A patent/CA2269031C/en not_active Expired - Fee Related
- 1997-10-16 EP EP97910115A patent/EP0946174B1/en not_active Expired - Lifetime
- 1997-10-16 JP JP10518563A patent/JP2001502336A/en active Pending
- 1997-10-16 WO PCT/US1997/018601 patent/WO1998016225A1/en active IP Right Grant
- 1997-10-16 AT AT97910115T patent/ATE271867T1/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CA2269031A1 (en) | 1998-04-23 |
US5877198A (en) | 1999-03-02 |
AU729675B2 (en) | 2001-02-08 |
DE69730045T2 (en) | 2005-07-21 |
WO1998016225A1 (en) | 1998-04-23 |
EP0946174B1 (en) | 2004-07-28 |
ATE271867T1 (en) | 2004-08-15 |
JP2001502336A (en) | 2001-02-20 |
IL129267A (en) | 2003-10-31 |
DE69730045D1 (en) | 2004-09-02 |
CA2269031C (en) | 2003-09-09 |
EP0946174A1 (en) | 1999-10-06 |
EP0946174A4 (en) | 2002-10-23 |
AU4757297A (en) | 1998-05-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
MM9K | Patent not in force due to non-payment of renewal fees |