IL111021A0 - Factor derived from muscle cells - Google Patents

Factor derived from muscle cells

Info

Publication number
IL111021A0
IL111021A0 IL11102194A IL11102194A IL111021A0 IL 111021 A0 IL111021 A0 IL 111021A0 IL 11102194 A IL11102194 A IL 11102194A IL 11102194 A IL11102194 A IL 11102194A IL 111021 A0 IL111021 A0 IL 111021A0
Authority
IL
Israel
Prior art keywords
substance
cells
cancer
muscle cells
proliferation
Prior art date
Application number
IL11102194A
Original Assignee
Mor Research Applic Ltd
Univ Bar Ilan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mor Research Applic Ltd, Univ Bar Ilan filed Critical Mor Research Applic Ltd
Priority to IL11102194A priority Critical patent/IL111021A0/en
Publication of IL111021A0 publication Critical patent/IL111021A0/en
Priority to US08/531,783 priority patent/US5962331A/en
Priority to DE69526096T priority patent/DE69526096T2/en
Priority to EP95934498A priority patent/EP0782452B1/en
Priority to KR1019970701853A priority patent/KR100392996B1/en
Priority to RU97106333/13A priority patent/RU2199327C2/en
Priority to PCT/US1995/012093 priority patent/WO1996009060A1/en
Priority to AT95934498T priority patent/ATE214934T1/en
Priority to CNB951963368A priority patent/CN1146432C/en
Priority to BR9509154A priority patent/BR9509154A/en
Priority to CA002198727A priority patent/CA2198727C/en
Priority to DK95934498T priority patent/DK0782452T3/en
Priority to AU36816/95A priority patent/AU692931B2/en
Priority to MX9702174A priority patent/MX9702174A/en
Priority to IL11541595A priority patent/IL115415A/en
Priority to ES95934498T priority patent/ES2174963T3/en
Priority to JP51109996A priority patent/JP3778366B2/en
Priority to FI971190A priority patent/FI113153B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/34—Muscles; Smooth muscle cells; Heart; Cardiac stem cells; Myoblasts; Myocytes; Cardiomyocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/16—Blood plasma; Blood serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/91—Cell lines ; Processes using cell lines

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Cardiology (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Vascular Medicine (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Stabilization Of Oscillater, Synchronisation, Frequency Synthesizers (AREA)
  • Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
  • Sorption Type Refrigeration Machines (AREA)
  • Led Devices (AREA)
  • Medicinal Preparation (AREA)

Abstract

A substance secreted or shed by muscle cells and white blood cells is disclosed. This novel substance is active in inhibiting proliferation of tumor cells and proliferation of stimulated lymphocytes. The substance does not inhibit proliferation of normal cells. This substance is used in accordance with the invention for treatment or prevention of cancer and the level of said substance in a body fluid or in a fluid conditioned by the growth therein of cells withdrawn from the individual, is used for the diagnosis of cancer or the level of risk of the individual of developing cancer.
IL11102194A 1994-09-22 1994-09-22 Factor derived from muscle cells IL111021A0 (en)

Priority Applications (18)

Application Number Priority Date Filing Date Title
IL11102194A IL111021A0 (en) 1994-09-22 1994-09-22 Factor derived from muscle cells
US08/531,783 US5962331A (en) 1994-09-22 1995-09-21 Cell growth regulator
JP51109996A JP3778366B2 (en) 1994-09-22 1995-09-22 Cell growth regulator
CNB951963368A CN1146432C (en) 1994-09-22 1995-09-22 Cell growth regulator
BR9509154A BR9509154A (en) 1994-09-22 1995-09-22 Cell growth regulator Processes for the treatment or prevention of a disease or disorder for the diagnosis of an individual's cancerous state or for determining the risk of an individual developing cancer for the preparation of cell growth regulator and composition
KR1019970701853A KR100392996B1 (en) 1994-09-22 1995-09-22 Cell growth regulators
RU97106333/13A RU2199327C2 (en) 1994-09-22 1995-09-22 Purified cellular growth regulator, method for its obtaining (versions), method for treating, preventing and predicting pulmonary cancer, composition for inhibiting cellular growth
PCT/US1995/012093 WO1996009060A1 (en) 1994-09-22 1995-09-22 Cell growth regulator
AT95934498T ATE214934T1 (en) 1994-09-22 1995-09-22 GROWTH REGULATOR
DE69526096T DE69526096T2 (en) 1994-09-22 1995-09-22 GROWTH REGULATOR
EP95934498A EP0782452B1 (en) 1994-09-22 1995-09-22 Cell growth regulator
CA002198727A CA2198727C (en) 1994-09-22 1995-09-22 Cell growth regulator
DK95934498T DK0782452T3 (en) 1994-09-22 1995-09-22 Cell Growth Regulator
AU36816/95A AU692931B2 (en) 1994-09-22 1995-09-22 Cell growth regulator
MX9702174A MX9702174A (en) 1994-09-22 1995-09-22 Cell growth regulator.
IL11541595A IL115415A (en) 1994-09-22 1995-09-22 Growth regulator having low molecular weight, endogenously present in white blood cells and muscle cells, compositions containing it, processes for its obtainment and various uses thereof
ES95934498T ES2174963T3 (en) 1994-09-22 1995-09-22 CELLULAR GROWTH REGULATOR.
FI971190A FI113153B (en) 1994-09-22 1997-03-21 Cell Growth

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL11102194A IL111021A0 (en) 1994-09-22 1994-09-22 Factor derived from muscle cells

Publications (1)

Publication Number Publication Date
IL111021A0 true IL111021A0 (en) 1994-11-28

Family

ID=11066570

Family Applications (2)

Application Number Title Priority Date Filing Date
IL11102194A IL111021A0 (en) 1994-09-22 1994-09-22 Factor derived from muscle cells
IL11541595A IL115415A (en) 1994-09-22 1995-09-22 Growth regulator having low molecular weight, endogenously present in white blood cells and muscle cells, compositions containing it, processes for its obtainment and various uses thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL11541595A IL115415A (en) 1994-09-22 1995-09-22 Growth regulator having low molecular weight, endogenously present in white blood cells and muscle cells, compositions containing it, processes for its obtainment and various uses thereof

Country Status (17)

Country Link
US (1) US5962331A (en)
EP (1) EP0782452B1 (en)
JP (1) JP3778366B2 (en)
KR (1) KR100392996B1 (en)
CN (1) CN1146432C (en)
AT (1) ATE214934T1 (en)
AU (1) AU692931B2 (en)
BR (1) BR9509154A (en)
CA (1) CA2198727C (en)
DE (1) DE69526096T2 (en)
DK (1) DK0782452T3 (en)
ES (1) ES2174963T3 (en)
FI (1) FI113153B (en)
IL (2) IL111021A0 (en)
MX (1) MX9702174A (en)
RU (1) RU2199327C2 (en)
WO (1) WO1996009060A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6133416A (en) * 1996-08-23 2000-10-17 The University Of Texas System Board Of Regents Inhibition of cell growth by an anti-proliferative factor
IL131096A (en) * 1999-07-26 2004-09-27 Can Fite Technologies Ltd Method for preparing a composition derived from muscle tissue
US20030143282A1 (en) * 2002-01-28 2003-07-31 Pnina Fishman Adenosine A3 receptor agonist

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4708948A (en) * 1984-04-20 1987-11-24 The United States Of America As Represented By The Department Of Health And Human Services Substantially purified tumor growth inhibitory factor
US5242692A (en) * 1990-07-10 1993-09-07 Bar Ilan University Anti-metastatic factor

Also Published As

Publication number Publication date
EP0782452A1 (en) 1997-07-09
FI971190A0 (en) 1997-03-21
IL115415A (en) 2001-05-20
DE69526096D1 (en) 2002-05-02
FI971190A (en) 1997-03-21
JPH10509028A (en) 1998-09-08
FI113153B (en) 2004-03-15
AU3681695A (en) 1996-04-09
EP0782452B1 (en) 2002-03-27
CN1146432C (en) 2004-04-21
AU692931B2 (en) 1998-06-18
IL115415A0 (en) 1995-12-31
MX9702174A (en) 1998-04-30
CA2198727C (en) 2007-03-27
CA2198727A1 (en) 1996-03-28
DK0782452T3 (en) 2002-07-01
CN1164190A (en) 1997-11-05
JP3778366B2 (en) 2006-05-24
DE69526096T2 (en) 2002-09-26
BR9509154A (en) 1997-10-14
ES2174963T3 (en) 2002-11-16
US5962331A (en) 1999-10-05
WO1996009060A1 (en) 1996-03-28
RU2199327C2 (en) 2003-02-27
ATE214934T1 (en) 2002-04-15
KR100392996B1 (en) 2003-11-28

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