IL108784A0 - Use of 2h-1,2,4-benzothiadiazin-3(4h)-one 1,1-dioxide derivatives as noncompetitive antagonists of the mmda receptor - Google Patents
Use of 2h-1,2,4-benzothiadiazin-3(4h)-one 1,1-dioxide derivatives as noncompetitive antagonists of the mmda receptorInfo
- Publication number
- IL108784A0 IL108784A0 IL10878494A IL10878494A IL108784A0 IL 108784 A0 IL108784 A0 IL 108784A0 IL 10878494 A IL10878494 A IL 10878494A IL 10878494 A IL10878494 A IL 10878494A IL 108784 A0 IL108784 A0 IL 108784A0
- Authority
- IL
- Israel
- Prior art keywords
- benzothiadiazin
- dioxide derivatives
- noncompetitive antagonists
- mmda
- receptor
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Psychiatry (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Anesthesiology (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9302439A FR2702150B1 (fr) | 1993-03-03 | 1993-03-03 | Application de dérivés de 2H-1,2-4-benzothiadiazine-3(4H)-one-1,1-dioxyde comme antagonistes non compétitifs du récepteur NMDA. |
Publications (1)
Publication Number | Publication Date |
---|---|
IL108784A0 true IL108784A0 (en) | 1994-06-24 |
Family
ID=9444603
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL10878494A IL108784A0 (en) | 1993-03-03 | 1994-02-28 | Use of 2h-1,2,4-benzothiadiazin-3(4h)-one 1,1-dioxide derivatives as noncompetitive antagonists of the mmda receptor |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP0687178A1 (xx) |
JP (1) | JPH08507303A (xx) |
AU (1) | AU6143694A (xx) |
CA (1) | CA2153951A1 (xx) |
FR (1) | FR2702150B1 (xx) |
HU (1) | HU9502572D0 (xx) |
IL (1) | IL108784A0 (xx) |
NO (1) | NO953387L (xx) |
PL (1) | PL310439A1 (xx) |
WO (1) | WO1994020109A1 (xx) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7732162B2 (en) | 2003-05-05 | 2010-06-08 | Probiodrug Ag | Inhibitors of glutaminyl cyclase for treating neurodegenerative diseases |
WO2008055945A1 (en) | 2006-11-09 | 2008-05-15 | Probiodrug Ag | 3-hydr0xy-1,5-dihydr0-pyrr0l-2-one derivatives as inhibitors of glutaminyl cyclase for the treatment of ulcer, cancer and other diseases |
SI2091948T1 (sl) | 2006-11-30 | 2012-07-31 | Probiodrug Ag | Novi inhibitorji glutaminil ciklaze |
ZA200905537B (en) | 2007-03-01 | 2010-10-27 | Probiodrug Ag | New use of glutaminyl cyclase inhibitors |
EP2142514B1 (en) | 2007-04-18 | 2014-12-24 | Probiodrug AG | Thiourea derivatives as glutaminyl cyclase inhibitors |
ES2548913T3 (es) | 2009-09-11 | 2015-10-21 | Probiodrug Ag | Derivados heterocíclicos como inhibidores de glutaminil ciclasa |
JP6026284B2 (ja) | 2010-03-03 | 2016-11-16 | プロビオドルグ エージー | グルタミニルシクラーゼの阻害剤 |
JP5688745B2 (ja) | 2010-03-10 | 2015-03-25 | プロビオドルグ エージー | グルタミニルシクラーゼ(qc、ec2.3.2.5)の複素環阻害剤 |
WO2011131748A2 (en) | 2010-04-21 | 2011-10-27 | Probiodrug Ag | Novel inhibitors |
WO2012123563A1 (en) | 2011-03-16 | 2012-09-20 | Probiodrug Ag | Benz imidazole derivatives as inhibitors of glutaminyl cyclase |
EP3461819B1 (en) | 2017-09-29 | 2020-05-27 | Probiodrug AG | Inhibitors of glutaminyl cyclase |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB975925A (en) * | 1961-02-21 | 1964-11-25 | Scherico Ltd | 3,4-dihydro-1,2,4-benzothiadiazine-1,1-dioxides |
US4716161A (en) * | 1984-04-17 | 1987-12-29 | Mitsubishi Chemical Industries Limited | Phenylpiperazine derivatives and their acid addition salts |
FR2675801A1 (fr) * | 1991-04-24 | 1992-10-30 | Rhone Poulenc Rorer Sa | Piperidines, leur preparation et les medicaments les contenant. |
WO1993021170A1 (fr) * | 1992-04-15 | 1993-10-28 | Rhone-Poulenc Rorer S.A. | Derives d'acide 3,4-dihydro-2h-1,2,4-benzothiadiazine 1,1-dioxyde-3-carboxylique, leur preparation et les medicaments les contenant |
FR2690160A1 (fr) * | 1992-04-15 | 1993-10-22 | Rhone Poulenc Rorer Sa | Application de dérivés d'acide 2H-1,2,4-benzothiadiazine-1,1-dioxyde-3-carboxylique à la préparation de médicaments, les produits nouveaux, leur préparation et les médicaments les contenant. |
-
1993
- 1993-03-03 FR FR9302439A patent/FR2702150B1/fr not_active Expired - Fee Related
-
1994
- 1994-02-25 JP JP6519646A patent/JPH08507303A/ja active Pending
- 1994-02-25 WO PCT/FR1994/000207 patent/WO1994020109A1/fr not_active Application Discontinuation
- 1994-02-25 HU HU9502572A patent/HU9502572D0/hu unknown
- 1994-02-25 CA CA002153951A patent/CA2153951A1/fr not_active Abandoned
- 1994-02-25 AU AU61436/94A patent/AU6143694A/en not_active Abandoned
- 1994-02-25 EP EP94908373A patent/EP0687178A1/fr not_active Withdrawn
- 1994-02-25 PL PL94310439A patent/PL310439A1/xx unknown
- 1994-02-28 IL IL10878494A patent/IL108784A0/xx unknown
-
1995
- 1995-08-29 NO NO953387A patent/NO953387L/no unknown
Also Published As
Publication number | Publication date |
---|---|
NO953387D0 (no) | 1995-08-29 |
FR2702150B1 (fr) | 1995-04-07 |
PL310439A1 (en) | 1995-12-11 |
CA2153951A1 (fr) | 1994-09-15 |
WO1994020109A1 (fr) | 1994-09-15 |
NO953387L (no) | 1995-08-29 |
HU9502572D0 (en) | 1995-11-28 |
EP0687178A1 (fr) | 1995-12-20 |
AU6143694A (en) | 1994-09-26 |
FR2702150A1 (fr) | 1994-09-09 |
JPH08507303A (ja) | 1996-08-06 |
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