IE862047L - Homogeneous process of immunoassay using luminescence¹technique - Google Patents
Homogeneous process of immunoassay using luminescence¹techniqueInfo
- Publication number
- IE862047L IE862047L IE862047A IE204786A IE862047L IE 862047 L IE862047 L IE 862047L IE 862047 A IE862047 A IE 862047A IE 204786 A IE204786 A IE 204786A IE 862047 L IE862047 L IE 862047L
- Authority
- IE
- Ireland
- Prior art keywords
- analyte
- addition
- reactant
- medium
- heavy atom
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Homogeneous process for the detection and/or determination by luminescence of an analyte in a medium susceptible of containing it by evidencing the product obtained by the reaction between the analyte and a corresponding receiver. Said process comprises 1) the addition to said medium of a first reactant comprised of an analyte receiver; 2) the addition of a second reactant comprised of at least one of the elements of the product obtained from the reaction of the analyte with at least one of its receivers, one of the two reactants being coupled with a luminescent compound and the other reactant comprising a heavy atom or patterns containing a heavy atom; 3) the incubation of the resulting medium either after the addition of each reactant or after the addition of both reactants; 4) excitation of the resulting medium; and 5) measuring, in balance or kinetic conditions, the signal emitted by the luminescent compound, said signal being modulated by the heavy atom effect.
[WO8700927A1]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8511905A FR2585836B1 (en) | 1985-08-02 | 1985-08-02 | HOMOGENEOUS METHOD FOR LUMINESCENCE DETECTION AND / OR DETERMINATION OF AN ANALYTE IN A MEDIUM CONTAINING IT |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE862047L true IE862047L (en) | 1987-02-02 |
| IE59302B1 IE59302B1 (en) | 1994-02-09 |
Family
ID=9321947
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE204786A IE59302B1 (en) | 1985-08-02 | 1986-07-30 | Homogeneous process for the detection and/or determination by luminescence of an analyte in a medium in which it may be present |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0232348B1 (en) |
| JP (1) | JPH0758291B2 (en) |
| KR (1) | KR880700270A (en) |
| AU (1) | AU595821B2 (en) |
| CA (1) | CA1279260C (en) |
| ES (1) | ES2000593A6 (en) |
| FR (1) | FR2585836B1 (en) |
| IE (1) | IE59302B1 (en) |
| IL (1) | IL79592A0 (en) |
| WO (1) | WO1987000927A1 (en) |
| ZA (1) | ZA865767B (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2617974B1 (en) * | 1987-07-07 | 1992-11-13 | Stabiligen | IMMUNOLOGICAL ASSAY PROCESS BY BIO- OR CHEMIO-LUMINESCENCE |
| JPH0737986B2 (en) * | 1988-03-29 | 1995-04-26 | 松下電器産業株式会社 | Immunological detection method |
| JP2599974B2 (en) * | 1988-09-13 | 1997-04-16 | 積水化学工業株式会社 | Voice detection method |
| JP2559475B2 (en) * | 1988-09-22 | 1996-12-04 | 積水化学工業株式会社 | Voice detection method |
| CA2384523C (en) * | 1991-03-04 | 2007-01-09 | Bayer Corporation | Automated analyzer |
| FR2768817B1 (en) * | 1997-09-19 | 1999-12-10 | Cis Bio Int | HOMOGENEOUS METHOD FOR THE DETECTION AND/OR DETERMINATION OF THE PHOSPHORYLATING ACTIVITY OF A BIOLOGICAL MATERIAL |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3996345A (en) * | 1974-08-12 | 1976-12-07 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
| AU531777B2 (en) * | 1978-04-05 | 1983-09-08 | Syva Co. | Label/solid conjugate immunoassay system |
| US4277437A (en) * | 1978-04-05 | 1981-07-07 | Syva Company | Kit for carrying out chemically induced fluorescence immunoassay |
| US4195072A (en) * | 1978-07-05 | 1980-03-25 | Abbott Laboratories | Stabilized platelet factor 4 immunoassay standards |
| US4318707A (en) * | 1978-11-24 | 1982-03-09 | Syva Company | Macromolecular fluorescent quencher particle in specific receptor assays |
| CA1121345A (en) * | 1979-03-05 | 1982-04-06 | Robert A. Yoshida | Method for competitive protein binding assays inhibiting non-specific interference |
| US4261968A (en) * | 1979-05-10 | 1981-04-14 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
| SE454115B (en) * | 1982-09-13 | 1988-03-28 | Wallac Oy | HOMOGENIC PHASE ANALYSIS WITH LANTANIDE KELAT AS BRAND SUBSTANCE |
| EP0200960A1 (en) * | 1985-05-08 | 1986-11-12 | Abbott Laboratories | Total estriol fluorescence polarization immunoassay |
-
1985
- 1985-08-02 FR FR8511905A patent/FR2585836B1/en not_active Expired
-
1986
- 1986-07-30 IE IE204786A patent/IE59302B1/en not_active IP Right Cessation
- 1986-07-31 JP JP61504184A patent/JPH0758291B2/en not_active Expired - Fee Related
- 1986-07-31 KR KR1019870700284A patent/KR880700270A/en not_active Application Discontinuation
- 1986-07-31 WO PCT/FR1986/000269 patent/WO1987000927A1/en active IP Right Grant
- 1986-07-31 AU AU61473/86A patent/AU595821B2/en not_active Ceased
- 1986-07-31 EP EP86904837A patent/EP0232348B1/en not_active Expired - Lifetime
- 1986-08-01 ZA ZA865767A patent/ZA865767B/en unknown
- 1986-08-01 IL IL79592A patent/IL79592A0/en not_active IP Right Cessation
- 1986-08-01 CA CA000515159A patent/CA1279260C/en not_active Expired - Lifetime
- 1986-08-01 ES ES8600821A patent/ES2000593A6/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| AU595821B2 (en) | 1990-04-12 |
| JPS63500399A (en) | 1988-02-12 |
| IL79592A0 (en) | 1986-11-30 |
| ZA865767B (en) | 1987-04-29 |
| EP0232348A1 (en) | 1987-08-19 |
| AU6147386A (en) | 1987-03-05 |
| FR2585836B1 (en) | 1987-11-27 |
| CA1279260C (en) | 1991-01-22 |
| JPH0758291B2 (en) | 1995-06-21 |
| FR2585836A1 (en) | 1987-02-06 |
| IE59302B1 (en) | 1994-02-09 |
| ES2000593A6 (en) | 1988-03-01 |
| KR880700270A (en) | 1988-02-22 |
| WO1987000927A1 (en) | 1987-02-12 |
| EP0232348B1 (en) | 1991-06-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Patent lapsed |