IE800362L - Therapeutic compositions - Google Patents
Therapeutic compositionsInfo
- Publication number
- IE800362L IE800362L IE800362A IE36280A IE800362L IE 800362 L IE800362 L IE 800362L IE 800362 A IE800362 A IE 800362A IE 36280 A IE36280 A IE 36280A IE 800362 L IE800362 L IE 800362L
- Authority
- IE
- Ireland
- Prior art keywords
- therapeutic compositions
- compositions
- fluoruracil
- isocyanurate
- derivatives
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 230000001225 therapeutic effect Effects 0.000 title abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- SNKDCTFPQUHAPR-UHFFFAOYSA-N 1-fluoropyrimidine-2,4-dione Chemical compound FN1C=CC(=O)NC1=O SNKDCTFPQUHAPR-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000002152 alkylating effect Effects 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 230000001085 cytostatic effect Effects 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- ZFSLODLOARCGLH-UHFFFAOYSA-N isocyanuric acid Chemical compound OC1=NC(O)=NC(O)=N1 ZFSLODLOARCGLH-UHFFFAOYSA-N 0.000 abstract 1
- HAWPXGHAZFHHAD-UHFFFAOYSA-N mechlorethamine Chemical class ClCCN(C)CCCl HAWPXGHAZFHHAD-UHFFFAOYSA-N 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
A therapeutic composition with cytostatic action comprising an isocyanurate having the formula I <IMAGE> in which R, R', and R'' which may be the same or different represent hydrogen or alkyl having from 1 to 4 carbon atoms, preferably hydrogen or methyl in an inert pharmaceutically acceptable diluent, carrier or vehicle. The compositions may also contain other alkylating substances such as derivatives of nitrogen mustard or fluoruracil.
[EP0014981A2]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2907349A DE2907349C2 (en) | 1979-02-24 | 1979-02-24 | Medicines with cytostatic activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE800362L true IE800362L (en) | 1980-08-24 |
| IE49274B1 IE49274B1 (en) | 1985-09-04 |
Family
ID=6063886
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE362/80A IE49274B1 (en) | 1979-02-24 | 1980-02-22 | Therapeutic compositions with cytostatic action |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0014981B1 (en) |
| JP (1) | JPS55118484A (en) |
| AT (1) | ATE716T1 (en) |
| AU (1) | AU536270B2 (en) |
| BE (1) | BE881834A (en) |
| CA (1) | CA1123740A (en) |
| CH (1) | CH645893A5 (en) |
| DE (1) | DE2907349C2 (en) |
| FR (1) | FR2449451A1 (en) |
| GB (1) | GB2044614B (en) |
| IE (1) | IE49274B1 (en) |
| IL (1) | IL59453A (en) |
| IT (1) | IT1147330B (en) |
| LU (1) | LU82190A1 (en) |
| NL (1) | NL8001100A (en) |
| NZ (1) | NZ192945A (en) |
| SE (1) | SE8001425L (en) |
| ZA (1) | ZA801017B (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT371816B (en) * | 1979-10-08 | 1983-08-10 | Henkel Kgaa | METHOD FOR PRODUCING NEW ISOCYANURS [UREDERIVATIVES |
| ATE22080T1 (en) * | 1980-01-31 | 1986-09-15 | Henkel Kgaa | PHARMACEUTICALS WITH CYTOSTATIC EFFECT AND USE OF N-HETEROCYCLIC RING COMPOUNDS MULTIPLE SUBSTITUTED BY GLYCIDYL GROUPS IN PHARMACEUTICAL PREPARATIONS. |
| AT372382B (en) * | 1980-08-14 | 1983-09-26 | Henkel Kgaa | METHOD FOR PRODUCING NEW OXIRANYLISOCYANURIC ACID COMPOUNDS |
| DE3131365A1 (en) * | 1981-08-07 | 1983-02-24 | Henkel KGaA, 4000 Düsseldorf | NEW DIGLYCIDYL-SUBSTITUTED HETEROCYCLIC COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE IN PHARMACEUTICAL PREPARATIONS WITH CYTOSTATIC EFFECTIVENESS |
| DE3131396A1 (en) * | 1981-08-07 | 1983-03-24 | Henkel KGaA, 4000 Düsseldorf | "NEW DIGLYCIDYL-PTERIDINE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE IN MEDICINAL PRODUCTS WITH A CYTOSTATIC EFFECT" |
| DE3133077A1 (en) * | 1981-08-21 | 1983-03-10 | Henkel KGaA, 4000 Düsseldorf | NEW 1,3,2-OXAZAPHOSPHORINE COMPOUNDS CONTAINING NEW CYTOSTATICALLY EFFECTIVE EPOXY GROUPS, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE IN PHARMACEUTICAL PREPARATIONS |
| TWI243169B (en) * | 1998-03-02 | 2005-11-11 | Nissan Chemical Ind Ltd | Optically active epoxy compound |
-
1979
- 1979-02-24 DE DE2907349A patent/DE2907349C2/en not_active Expired
-
1980
- 1980-02-18 EP EP80100806A patent/EP0014981B1/en not_active Expired
- 1980-02-18 AT AT80100806T patent/ATE716T1/en not_active IP Right Cessation
- 1980-02-21 BE BE0/199482A patent/BE881834A/en not_active IP Right Cessation
- 1980-02-22 GB GB8006109A patent/GB2044614B/en not_active Expired
- 1980-02-22 IL IL59453A patent/IL59453A/en unknown
- 1980-02-22 CH CH143980A patent/CH645893A5/en not_active IP Right Cessation
- 1980-02-22 NL NL8001100A patent/NL8001100A/en not_active Application Discontinuation
- 1980-02-22 LU LU82190A patent/LU82190A1/en unknown
- 1980-02-22 IT IT20100/80A patent/IT1147330B/en active
- 1980-02-22 AU AU55830/80A patent/AU536270B2/en not_active Ceased
- 1980-02-22 ZA ZA00801017A patent/ZA801017B/en unknown
- 1980-02-22 NZ NZ192945A patent/NZ192945A/en unknown
- 1980-02-22 IE IE362/80A patent/IE49274B1/en unknown
- 1980-02-22 SE SE8001425A patent/SE8001425L/en not_active Application Discontinuation
- 1980-02-22 FR FR8003962A patent/FR2449451A1/en active Granted
- 1980-02-23 JP JP2214580A patent/JPS55118484A/en active Granted
- 1980-02-25 CA CA346,385A patent/CA1123740A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| AU5583080A (en) | 1980-09-04 |
| IL59453A (en) | 1984-02-29 |
| GB2044614A (en) | 1980-10-22 |
| GB2044614B (en) | 1983-01-26 |
| LU82190A1 (en) | 1980-09-24 |
| IL59453A0 (en) | 1980-05-30 |
| AU536270B2 (en) | 1984-05-03 |
| BE881834A (en) | 1980-08-21 |
| IT8020100A0 (en) | 1980-02-22 |
| CH645893A5 (en) | 1984-10-31 |
| JPS6354688B2 (en) | 1988-10-28 |
| EP0014981B1 (en) | 1982-02-24 |
| DE2907349C2 (en) | 1982-09-16 |
| JPS55118484A (en) | 1980-09-11 |
| NZ192945A (en) | 1984-05-31 |
| ZA801017B (en) | 1981-02-25 |
| EP0014981A3 (en) | 1981-02-11 |
| DE2907349A1 (en) | 1980-08-28 |
| CA1123740A (en) | 1982-05-18 |
| IT1147330B (en) | 1986-11-19 |
| IE49274B1 (en) | 1985-09-04 |
| SE8001425L (en) | 1980-08-25 |
| FR2449451B1 (en) | 1982-12-10 |
| FR2449451A1 (en) | 1980-09-19 |
| NL8001100A (en) | 1980-08-26 |
| EP0014981A2 (en) | 1980-09-03 |
| ATE716T1 (en) | 1982-03-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU8046891A (en) | Pyrazolopyridine compound and processes for preparation thereof | |
| CA2123052A1 (en) | Monomeric bile acid derivatives, processes for their preparation and the use of these compounds as medicaments | |
| AU4950993A (en) | Combination of germicidal agents | |
| CA2160137A1 (en) | Bicyclic Ansamycins | |
| UA37230C2 (en) | poly-1-n-alkenamines and compositions of fuel or lubricant agent containing them | |
| AU4218093A (en) | New peptides derived from trifluoromethyl ketones, process for their preparation and the pharmaceutical compositions which contain them | |
| IE830785L (en) | Pharmaceutical compositions containing oxicam derivatives | |
| IE800327L (en) | N-substituted aziridine-2-carboxylic acid derivatives | |
| CA2071248A1 (en) | Composition containing dioxabicyclo-[3.3.0]octane derivative | |
| CA2053820A1 (en) | Method of Inhibiting Metabolism of Cholesterol | |
| AU4223696A (en) | Preventive or alleviative agent for hypertension or medical symptoms caused thereby | |
| IE800362L (en) | Therapeutic compositions | |
| UA37311C2 (en) | Compound for treating sexual dysfunction and pharmaceutical composition | |
| IL110894A0 (en) | Cephem derivatives, processes for the preparation thereof, and pharmaceutical compositions containing the same | |
| AU2998592A (en) | Pharmaceutical composition for the improvement of dysuria | |
| AU4375389A (en) | Pyrrolidine derivatives | |
| PL312966A1 (en) | Derivatives of thiocarbamoil | |
| EP0370712A3 (en) | Ethylamine derivatives and hypotensives containing the same | |
| WO1998054211A3 (en) | Cyclodepsipeptides and pharmaceutical compositions containing them | |
| EP0551952A3 (en) | 17-aryl-substituted steroidal compounds active on the cardiovascular system | |
| IE812421L (en) | Peptides |