IE800115L - Pharmaceutical compositions, containing a benzo £c| £1,6|¹naphthyridine - Google Patents

Pharmaceutical compositions, containing a benzo £c| £1,6|¹naphthyridine

Info

Publication number
IE800115L
IE800115L IE800115A IE11580A IE800115L IE 800115 L IE800115 L IE 800115L IE 800115 A IE800115 A IE 800115A IE 11580 A IE11580 A IE 11580A IE 800115 L IE800115 L IE 800115L
Authority
IE
Ireland
Prior art keywords
carbon atoms
hydrogen
chlorine
alkoxy
alkyl
Prior art date
Application number
IE800115A
Original Assignee
Sandoz Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ltd filed Critical Sandoz Ltd
Publication of IE800115L publication Critical patent/IE800115L/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Pharmaceutical compositions containing A) a compound of formula I, <IMAGE> wherein either i) R1 is hydrogen, alkyl of 1 to 3 carbon atoms, alkoxy of 1 to 3 carbon atoms or alkylthio of 1 to 3 carbon atoms, fluorine, bromine, chlorine, nitro, trifluoromethyl, amino or -NHCOR, wherein -COR is alkanoyl of 1 to 18 carbon atoms; benzoyl; benzoyl wherein the benzene ring is substituted by one X and one Y, X being alkyl of 1 to 4 carbon atoms, alkoxy of 1 to 4 carbon atoms, fluorine, chlorine or bromine, and Y being hydrogen, alkyl of 1 to 4 carbon atoms, alkoxy of 1 to 4 carbon atoms, or chlorine; phenylalkanoyl, wherein the alkylene section has 1 to 3 carbon atoms; cinnamoyl; phenylalkanoyl as defined above or cinnamoyl which are substitute in the benzene ring by one X and one Y which are as defined above; or -COA, A being thienyl, furyl, pyrrolyl or pyridyl; R2 is hydrogen, chlorine, alkyl of 1 to 3 carbon atoms or alkoxy of 1 to 3 carbon atoms and either R3 and R4 are both hydrogen or both methoxy or R3 and R4 together are methylene-dioxy, or ii) R1 is -NHCOR min , wherein R min is dichloromethyl, cycloalkyl of 3 to 6 carbon atoms or alkenyl of 2 to 5 carbon atoms, R2 is hydrogen and R3 and R4 are both methoxy and B) a beta -adrenoceptor blocking agent, are used in the treatment of coronary heart disease and myocardial infarction. [GB2040682A]
IE800115A 1979-01-22 1980-01-21 Pharmaceutical compositions, containing a benzo £c| £1,6|¹naphthyridine IE800115L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7902147 1979-01-22

Publications (1)

Publication Number Publication Date
IE800115L true IE800115L (en) 1980-07-22

Family

ID=10502644

Family Applications (1)

Application Number Title Priority Date Filing Date
IE800115A IE800115L (en) 1979-01-22 1980-01-21 Pharmaceutical compositions, containing a benzo £c| £1,6|¹naphthyridine

Country Status (12)

Country Link
AU (1) AU5478180A (en)
BE (1) BE880455A (en)
DE (1) DE3001016A1 (en)
ES (1) ES487881A0 (en)
FR (1) FR2446636A1 (en)
GB (1) GB2040682A (en)
IE (1) IE800115L (en)
IL (1) IL59176A0 (en)
NL (1) NL8000332A (en)
PT (1) PT70715A (en)
SE (1) SE8000268L (en)
ZA (1) ZA80369B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3423003A1 (en) * 1984-06-22 1986-01-02 Beiersdorf Ag, 2000 Hamburg BENZO (C) (1,8) NAPHTHYRIDINE, METHOD FOR THE PRODUCTION AND USE THEREOF, AND PREPARATIONS CONTAINING THESE COMPOUNDS
US4652567A (en) * 1985-03-13 1987-03-24 Hoechst-Roussel Pharmaceuticals Inc. Benzo(c)-1,5-naphthyridines useful for treating a patient having drug induced memory impairment in need of memory enhancement

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1361441A (en) * 1970-05-13 1974-07-24 Sandoz Ltd Benzonaphthyridine derivatives
JPS5585519A (en) * 1978-12-11 1980-06-27 Sandoz Ag Novel use of benzo*c**1*6*naphthyridine and medical composition containing same and betaablocking agent

Also Published As

Publication number Publication date
FR2446636A1 (en) 1980-08-14
NL8000332A (en) 1980-07-24
BE880455A (en) 1980-06-06
IL59176A0 (en) 1980-05-30
DE3001016A1 (en) 1980-07-31
SE8000268L (en) 1980-07-23
ZA80369B (en) 1981-08-26
PT70715A (en) 1980-02-01
ES8102126A1 (en) 1980-12-16
GB2040682A (en) 1980-09-03
ES487881A0 (en) 1980-12-16
AU5478180A (en) 1980-07-31

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