IE46170L - Prostanes - Google Patents

Prostanes

Info

Publication number
IE46170L
IE46170L IE772409A IE240977A IE46170L IE 46170 L IE46170 L IE 46170L IE 772409 A IE772409 A IE 772409A IE 240977 A IE240977 A IE 240977A IE 46170 L IE46170 L IE 46170L
Authority
IE
Ireland
Prior art keywords
mammals
compounds
pentanor
acid production
gastric acid
Prior art date
Application number
IE772409A
Other versions
IE46170B1 (en
Original Assignee
Ici Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ici Plc filed Critical Ici Plc
Publication of IE46170L publication Critical patent/IE46170L/en
Publication of IE46170B1 publication Critical patent/IE46170B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/02—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D305/04—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D305/08—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/02—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D305/04—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D305/06—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D331/00—Heterocyclic compounds containing rings of less than five members, having one sulfur atom as the only ring hetero atom
    • C07D331/04—Four-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/65515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a five-membered ring
    • C07F9/65517—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a five-membered ring condensed with carbocyclic rings or carbocyclic ring systems

Abstract

The disclosure relates to novel .omega.-pentanor prostaglandin E analogs bearing a 4- or 5-membered O or S hetero-ring as 15-substituent, for example 15-(3-butyloxetan-3-yl)-ll.alpha.,15-dihydroxy-9-oxo-16,17,18,19,20-pentanor-5-cis,13-trans-prostadienoic acid, which are useful as inhibitors of gastric acid production in mammals, together with pharmaceutical and veterinary compositions containing such compounds, and a method of using such compounds to inhibit gastric acid production in mammals. [CA1119591A]
IE2409/77A 1976-12-08 1977-11-28 Prostane derivatives IE46170B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB51196/76A GB1550399A (en) 1976-12-08 1976-12-08 Prostane derivatives

Publications (2)

Publication Number Publication Date
IE46170L true IE46170L (en) 1978-06-08
IE46170B1 IE46170B1 (en) 1983-03-09

Family

ID=10459023

Family Applications (1)

Application Number Title Priority Date Filing Date
IE2409/77A IE46170B1 (en) 1976-12-08 1977-11-28 Prostane derivatives

Country Status (14)

Country Link
JP (1) JPS5371060A (en)
AU (1) AU3104477A (en)
BE (1) BE861652A (en)
CA (1) CA1119591A (en)
DE (1) DE2754741A1 (en)
DK (1) DK548177A (en)
FR (1) FR2373538A1 (en)
GB (1) GB1550399A (en)
IE (1) IE46170B1 (en)
IT (1) IT1089433B (en)
NL (1) NL7713587A (en)
NZ (1) NZ185822A (en)
SE (1) SE7713895L (en)
ZA (1) ZA777059B (en)

Also Published As

Publication number Publication date
ZA777059B (en) 1978-08-30
DE2754741A1 (en) 1978-06-15
FR2373538B1 (en) 1981-07-10
JPS5371060A (en) 1978-06-24
NL7713587A (en) 1978-06-12
GB1550399A (en) 1979-08-15
AU3104477A (en) 1979-06-07
NZ185822A (en) 1979-03-16
SE7713895L (en) 1978-06-09
FR2373538A1 (en) 1978-07-07
IT1089433B (en) 1985-06-18
DK548177A (en) 1978-06-09
BE861652A (en) 1978-06-08
CA1119591A (en) 1982-03-09
IE46170B1 (en) 1983-03-09

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