IE45850L - PYRIMIDO (6,1-a) ISOQUINOLINE DERIVATIVES. - Google Patents

PYRIMIDO (6,1-a) ISOQUINOLINE DERIVATIVES.

Info

Publication number
IE45850L
IE45850L IE772498A IE249877A IE45850L IE 45850 L IE45850 L IE 45850L IE 772498 A IE772498 A IE 772498A IE 249877 A IE249877 A IE 249877A IE 45850 L IE45850 L IE 45850L
Authority
IE
Ireland
Prior art keywords
pyrimido
properties
derivatives
isoquinolin
preparation
Prior art date
Application number
IE772498A
Other versions
IE45850B1 (en
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IN433/BOM/76A external-priority patent/IN147624B/en
Priority claimed from DE19772720085 external-priority patent/DE2720085A1/en
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of IE45850L publication Critical patent/IE45850L/en
Publication of IE45850B1 publication Critical patent/IE45850B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509—Six-membered rings
    • C07F9/650905—Six-membered rings having the nitrogen atoms in the positions 1 and 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

HOE 77/F 091 PYRIMIDO (6,1-a)ISOQUINOLIN-4-ONE DERIVATIVES of the disclosure: A novel class of pyrimido (6,1-a)isoquinolin-4-one derivatives, new intermediates used in their preparation and processes for the preparation of the intermediates and the compounds of the invention are described. The pyrimido(6,1-a)isouqinolin-4-one derivatives of the invention possess valuable pharmacologicla properties, for example blood pressure lowering properties, bronchodilatory properties and anti-allergic properties. [CA1140123A]
IE2498/77A 1976-12-10 1977-12-09 Pyrimido (6,1-a) isoquinolin-4-one derivatives IE45850B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN433/BOM/76A IN147624B (en) 1976-12-10 1976-12-10
DE19772720085 DE2720085A1 (en) 1977-05-05 1977-05-05 PYRIMIDO (6.1-A) ISOCHINOLIN-2-ON DERIVATIVES

Publications (2)

Publication Number Publication Date
IE45850L true IE45850L (en) 1978-06-10
IE45850B1 IE45850B1 (en) 1982-12-15

Family

ID=25771976

Family Applications (1)

Application Number Title Priority Date Filing Date
IE2498/77A IE45850B1 (en) 1976-12-10 1977-12-09 Pyrimido (6,1-a) isoquinolin-4-one derivatives

Country Status (6)

Country Link
AU (2) AU527997B2 (en)
CA (1) CA1140123A (en)
GB (1) GB1597717A (en)
IE (1) IE45850B1 (en)
NZ (1) NZ185900A (en)
PH (1) PH18224A (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3135831A1 (en) * 1981-09-10 1983-04-28 Hoechst Ag, 6230 Frankfurt 9,10-SUBSTITUTED 2-MESITYLIMINO-3-ALKYL-3,4,6,7-TETRAHYDRO-2H-PYRIMIDO (6.1-A) ISOCHINOLIN-4-ONE, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS A MEDICINAL PRODUCT
ZW6284A1 (en) * 1983-05-05 1985-10-30 Hoffmann La Roche Novel pyrimidone derivatives
DE60005493T2 (en) * 1999-03-31 2004-07-01 Vernalis Ltd., Wokingham Pyrimido [6,1-A] ISOCHINOLINONDERIVATE
GB201613054D0 (en) 2016-07-28 2016-09-14 Verona Pharma Plc New compound and process
WO2020011254A1 (en) 2018-07-13 2020-01-16 正大天晴药业集团股份有限公司 Fused tri-cyclic compound as pde3/pde4 dual inhibitor
JP2024517583A (en) * 2021-04-29 2024-04-23 ▲蘇▼州盛迪▲亞▼生物医▲薬▼有限公司 Isoquinolinone compounds and their uses

Also Published As

Publication number Publication date
AU3141177A (en) 1979-06-14
AU527997B2 (en) 1983-03-31
IE45850B1 (en) 1982-12-15
AU1586583A (en) 1983-12-22
CA1140123A (en) 1983-01-25
NZ185900A (en) 1981-04-24
PH18224A (en) 1985-04-30
GB1597717A (en) 1981-09-09

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