IE45392L - 3-tetrazolylthiomethyl-cephalosporins. - Google Patents

3-tetrazolylthiomethyl-cephalosporins.

Info

Publication number
IE45392L
IE45392L IE771439A IE143977A IE45392L IE 45392 L IE45392 L IE 45392L IE 771439 A IE771439 A IE 771439A IE 143977 A IE143977 A IE 143977A IE 45392 L IE45392 L IE 45392L
Authority
IE
Ireland
Prior art keywords
cephalosporins
tetrazolylthiomethyl
compounds
us4101656a
alkanesulfonamidoalkyl
Prior art date
Application number
IE771439A
Other versions
IE45392B1 (en
Original Assignee
Smithkline Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Corp filed Critical Smithkline Corp
Priority to IE2707/81A priority Critical patent/IE45393B1/en
Priority to IE2708/81A priority patent/IE45394B1/en
Publication of IE45392L publication Critical patent/IE45392L/en
Publication of IE45392B1 publication Critical patent/IE45392B1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D257/00Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04Five-membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

The compounds of this invention are cephalosporins having various acyl substituents at the 7-position and an alkanesulfonamidoalkyl substituted tetrazolylthiomethyl group at the 3-position of the cephem nucleus and intermediates for the preparation thereof. The 7-acylated compounds have antibacterial activity. [US4101656A]
IE1439/77A 1976-07-12 1977-07-12 Cephalosporin compounds IE45392B1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
IE2707/81A IE45393B1 (en) 1976-07-12 1977-07-12 Tetrazole-5-thiols
IE2708/81A IE45394B1 (en) 1976-07-12 1977-07-12 7-aminocephalosporin derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/704,141 US4101656A (en) 1976-07-12 1976-07-12 7β-Acylamino-3-(alkanesulfonamidoalkyl substituted tetrazolylthiomethyl) cephalosporins, antibacterial compositions containing them and methods of treating bacterial infections with them

Publications (2)

Publication Number Publication Date
IE45392L true IE45392L (en) 1978-01-12
IE45392B1 IE45392B1 (en) 1982-08-11

Family

ID=24828245

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1439/77A IE45392B1 (en) 1976-07-12 1977-07-12 Cephalosporin compounds

Country Status (11)

Country Link
US (1) US4101656A (en)
JP (1) JPS539793A (en)
BE (1) BE856638A (en)
CH (2) CH631988A5 (en)
DE (1) DE2731261A1 (en)
DK (1) DK305077A (en)
FR (3) FR2358408A1 (en)
GB (3) GB1589881A (en)
IE (1) IE45392B1 (en)
LU (1) LU77702A1 (en)
NL (1) NL7707751A (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4171368A (en) * 1975-10-30 1979-10-16 Smithkline Corporation 7-Acylamino-3-(sulfaminoalkyl substituted tetrazolylthiomethyl)cephalosporins, antibacterial compositions containing them and methods of treating bacterial infections with them
US4171433A (en) * 1975-10-30 1979-10-16 Smithkline Corporation 7-Amino-3-(sulfaminoalkyl substituted tetrazolylthiomethyl)cephalosporin intermediates for preparing 7-acylamino cephalosporins
US4171362A (en) * 1975-10-30 1979-10-16 Smithkline Corporation 7-Acylamino-3-(sulfaminoalkyl substituted tetrazolylthiomethyl)cephalosporins antibacterial compositions containing them and methods of treating bacterial infections with them
US4117123A (en) * 1977-06-09 1978-09-26 Smithkline Corporation 7-Acylamino-3-[1-(2-sulfamidoethyl)tetrazol-5-ylthiomethyl]-3-cephem-4-carboxylic acids
EP3792289A4 (en) 2018-07-27 2021-09-08 Denka Company Limited Method for producing polyvinyl alcohol

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE36221B1 (en) * 1971-04-21 1976-09-15 Ciba Geigy Ag Acylamino compounds and a process for their manufacture
AR207752A1 (en) 1973-03-30 1976-10-29 Fujisawa Pharmaceutical Co PROCEDURE FOR OBTAINING 7-AMINO-SUBSTITUTED-3-THIOMETHYL SUBSTITUTED-3-CEFEM-4-CARBOXYL ACIDS
JPS5734837B2 (en) * 1973-12-26 1982-07-26
GB1478055A (en) * 1973-07-27 1977-06-29 Erba Carlo Spa Cephalosporin compounds
NL7414119A (en) * 1973-10-31 1975-05-02 Fujisawa Pharmaceutical Co PROCESS FOR PREPARING 1H-TETRAZOL-5-THIOL DERIVATIVES AND 1-SUBSTITUATED 1H-TETRAZOL-5-THIOLS.
JPS5512913B2 (en) * 1974-11-13 1980-04-04
GB1509074A (en) 1974-04-05 1978-04-26 Yamanouchi Pharma Co Ltd Cephalosporin derivatives
JPS595596B2 (en) * 1974-04-26 1984-02-06 藤沢薬品工業株式会社 7- Chikan -3-N Ganyufuxocanethiomethyl -3- Cefem -4- Carbonsanyuudoutai no Seizouhou
US4297489A (en) * 1974-09-03 1981-10-27 Bristol-Myers Company 7-α-Amino-substituted acylamino-3-(1-carboxymethyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acids
US4066762A (en) * 1976-07-12 1978-01-03 Smithkline Corporation Derivatives of 7-(2-substituted-2-hydroxyiminoacetamido)-3-(1-substituted tetrazol-5-ylthiomethyl-3-cephem-4-carboxylic acid

Also Published As

Publication number Publication date
NL7707751A (en) 1978-01-16
IE45392B1 (en) 1982-08-11
GB1589882A (en) 1981-05-20
JPS539793A (en) 1978-01-28
FR2376862B1 (en) 1982-12-31
JPS6337106B2 (en) 1988-07-22
FR2358408A1 (en) 1978-02-10
US4101656A (en) 1978-07-18
DK305077A (en) 1978-01-13
FR2376853B1 (en) 1982-12-31
FR2376862A1 (en) 1978-08-04
GB1589881A (en) 1981-05-20
CH630371A5 (en) 1982-06-15
FR2376853A1 (en) 1978-08-04
LU77702A1 (en) 1977-10-05
BE856638A (en) 1978-01-09
DE2731261A1 (en) 1978-01-19
GB1589883A (en) 1981-05-20
CH631988A5 (en) 1982-09-15
FR2358408B1 (en) 1984-03-23

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