IE41199L - 1,5(6)-disubstituted benzimimazole-2-carbamates having¹anthelmintic and antifungal activity - Google Patents
1,5(6)-disubstituted benzimimazole-2-carbamates having¹anthelmintic and antifungal activityInfo
- Publication number
- IE41199L IE41199L IE741434A IE143474A IE41199L IE 41199 L IE41199 L IE 41199L IE 741434 A IE741434 A IE 741434A IE 143474 A IE143474 A IE 143474A IE 41199 L IE41199 L IE 41199L
- Authority
- IE
- Ireland
- Prior art keywords
- denotes
- benzimimazole
- carbamates
- disubstituted
- antifungal activity
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/30—Nitrogen atoms not forming part of a nitro radical
- C07D235/32—Benzimidazole-2-carbamic acids, unsubstituted or substituted; Esters thereof; Thio-analogues thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Fodder In General (AREA)
Abstract
Compounds of the formula <IMAGE> wherein R denotes C1-C4-alkyl, R<1> denotes various ether, thioether, sulphinyl and sulphonyl groups and R<8> denotes aryl, aralkyl or C1-C12-alkyl, which can be substituted by (C1-C4-alkoxy)-carbonyl, are prepared by reaction of a corresponding benzimidazole, which is however unsubstituted in the 1-position, with an isocyanate OCNR. The compounds and their salts with acids possess a broad-band activity against parasites of mammals, especially against helminths, and can be used for the treatment of corresponding infections of the digestive tract.
[GB1480722A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US473865A US3929822A (en) | 1972-12-29 | 1974-05-28 | 1,5(6)-Disubstituted benzizimidazole-2-carbamate derivatives having anthelmintic activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE41199L true IE41199L (en) | 1975-11-28 |
| IE41199B1 IE41199B1 (en) | 1979-11-07 |
Family
ID=23881335
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE1434/74A IE41199B1 (en) | 1974-05-28 | 1974-07-05 | 1,5(6)-disubstituted benzimidazole-2-carbamate derivativeshaving anthelmintic activity |
Country Status (21)
| Country | Link |
|---|---|
| JP (1) | JPS50155612A (en) |
| AR (1) | AR221575A1 (en) |
| AT (1) | AT337714B (en) |
| BE (1) | BE817164Q (en) |
| BR (1) | BR7406197A (en) |
| CH (1) | CH614943A5 (en) |
| CS (1) | CS222211B2 (en) |
| DD (1) | DD115494A6 (en) |
| DE (1) | DE2431093C2 (en) |
| DK (1) | DK155005C (en) |
| ES (1) | ES430794A1 (en) |
| GB (1) | GB1480722A (en) |
| HU (1) | HU169779B (en) |
| IE (1) | IE41199B1 (en) |
| IT (1) | IT1046279B (en) |
| PL (1) | PL100057B1 (en) |
| RO (1) | RO64921A (en) |
| SE (1) | SE414174B (en) |
| SU (1) | SU644385A3 (en) |
| YU (1) | YU37331B (en) |
| ZA (2) | ZA746666B (en) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3578676A (en) * | 1968-06-21 | 1971-05-11 | Smith Kline French Lab | Benzimidazole-2-carbamates substituted on the benzene ring with an acyloxyalkyl group |
| US3722322A (en) * | 1971-05-05 | 1973-03-27 | E Coeppert | Speed control device |
| BE793358A (en) * | 1971-12-27 | 1973-06-27 | Hoechst Ag | NEW 2-CARBALCOXY-AMINO-BENZIMIDAZOLE DERIVATIVES PRESENTING ANTHELMINTIC ACTIVITY AND THEIR PREPARATION PROCESS |
-
1974
- 1974-05-28 RO RO74473865A patent/RO64921A/en unknown
- 1974-06-19 SE SE7408108A patent/SE414174B/en not_active IP Right Cessation
- 1974-06-26 JP JP49073160A patent/JPS50155612A/ja active Pending
- 1974-06-27 YU YU1813/74A patent/YU37331B/en unknown
- 1974-06-27 CS CS744553A patent/CS222211B2/en unknown
- 1974-06-28 DK DK351774A patent/DK155005C/en not_active IP Right Cessation
- 1974-06-28 DE DE2431093A patent/DE2431093C2/en not_active Expired
- 1974-07-02 BE BE146141A patent/BE817164Q/en not_active IP Right Cessation
- 1974-07-03 GB GB29574/74A patent/GB1480722A/en not_active Expired
- 1974-07-05 IE IE1434/74A patent/IE41199B1/en unknown
- 1974-07-05 AT AT556274A patent/AT337714B/en not_active IP Right Cessation
- 1974-07-09 DD DD179816A patent/DD115494A6/xx unknown
- 1974-07-12 CH CH967674A patent/CH614943A5/en not_active IP Right Cessation
- 1974-07-19 SU SU742047767A patent/SU644385A3/en active
- 1974-07-26 BR BR6197/74A patent/BR7406197A/en unknown
- 1974-08-09 HU HUSI1425A patent/HU169779B/hu unknown
- 1974-08-20 PL PL1974173572A patent/PL100057B1/en unknown
- 1974-10-08 ES ES430794A patent/ES430794A1/en not_active Expired
- 1974-10-21 ZA ZA00746666A patent/ZA746666B/en unknown
- 1974-10-21 ZA ZA00746665A patent/ZA746665B/en unknown
- 1974-10-25 IT IT70183/74A patent/IT1046279B/en active
-
1981
- 1981-07-18 AR AR254768A patent/AR221575A1/en active
Also Published As
| Publication number | Publication date |
|---|---|
| SU644385A3 (en) | 1979-01-25 |
| CH614943A5 (en) | 1979-12-28 |
| DK351774A (en) | 1975-11-29 |
| ZA746666B (en) | 1976-06-30 |
| YU181374A (en) | 1983-04-27 |
| SE7408108L (en) | 1975-12-01 |
| BE817164Q (en) | 1975-01-02 |
| AT337714B (en) | 1977-07-11 |
| RO64921A (en) | 1979-07-15 |
| GB1480722A (en) | 1977-07-20 |
| ZA746665B (en) | 1976-05-26 |
| DE2431093A1 (en) | 1975-12-11 |
| PL100057B1 (en) | 1978-08-31 |
| DD115494A6 (en) | 1975-10-05 |
| DE2431093C2 (en) | 1982-12-02 |
| IE41199B1 (en) | 1979-11-07 |
| ES430794A1 (en) | 1977-08-01 |
| YU37331B (en) | 1984-08-31 |
| BR7406197A (en) | 1976-03-23 |
| DK155005B (en) | 1989-01-23 |
| IT1046279B (en) | 1980-06-30 |
| SE414174B (en) | 1980-07-14 |
| JPS50155612A (en) | 1975-12-16 |
| CS222211B2 (en) | 1983-05-27 |
| DK155005C (en) | 1989-06-05 |
| HU169779B (en) | 1977-02-28 |
| AR221575A1 (en) | 1981-02-27 |
| ATA556274A (en) | 1976-11-15 |
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