ID26326A - FATURES 2 PURIN 9 IL TETRAHIDEROFURAN 3.4 DIOL - Google Patents
FATURES 2 PURIN 9 IL TETRAHIDEROFURAN 3.4 DIOLInfo
- Publication number
- ID26326A ID26326A IDW20001467A ID20001467A ID26326A ID 26326 A ID26326 A ID 26326A ID W20001467 A IDW20001467 A ID W20001467A ID 20001467 A ID20001467 A ID 20001467A ID 26326 A ID26326 A ID 26326A
- Authority
- ID
- Indonesia
- Prior art keywords
- tetrahiderofuran
- fatures
- purin
- diol
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9802066.2A GB9802066D0 (en) | 1998-01-31 | 1998-01-31 | Chemical compounds |
GBGB9813528.8A GB9813528D0 (en) | 1998-06-23 | 1998-06-23 | Chemical compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
ID26326A true ID26326A (en) | 2000-12-14 |
Family
ID=26313042
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IDW20001467A ID26326A (en) | 1998-01-31 | 1999-01-29 | FATURES 2 PURIN 9 IL TETRAHIDEROFURAN 3.4 DIOL |
Country Status (39)
Country | Link |
---|---|
US (1) | US6762170B1 (en) |
EP (1) | EP1051425B1 (en) |
JP (1) | JP2002501928A (en) |
KR (1) | KR20010034473A (en) |
CN (1) | CN1289338A (en) |
AP (1) | AP2000001875A0 (en) |
AR (1) | AR014508A1 (en) |
AT (1) | ATE226957T1 (en) |
AU (1) | AU757183B2 (en) |
BG (1) | BG63783B1 (en) |
BR (1) | BR9907270A (en) |
CA (1) | CA2318278A1 (en) |
CO (1) | CO4980872A1 (en) |
DE (1) | DE69903708T2 (en) |
DK (1) | DK1051425T3 (en) |
EA (1) | EA003194B1 (en) |
EE (1) | EE200000441A (en) |
ES (1) | ES2186330T3 (en) |
GE (1) | GEP20022839B (en) |
HK (1) | HK1030611A1 (en) |
HR (1) | HRP20000511A2 (en) |
HU (1) | HUP0101305A3 (en) |
ID (1) | ID26326A (en) |
IL (1) | IL137042A0 (en) |
IS (1) | IS5550A (en) |
MA (1) | MA26601A1 (en) |
NO (1) | NO20003867L (en) |
NZ (1) | NZ505452A (en) |
OA (1) | OA11447A (en) |
PE (1) | PE20000280A1 (en) |
PL (1) | PL342670A1 (en) |
PT (1) | PT1051425E (en) |
SI (1) | SI1051425T1 (en) |
SK (1) | SK11192000A3 (en) |
SV (1) | SV1999000009A (en) |
TR (1) | TR200002218T2 (en) |
TW (1) | TW434250B (en) |
WO (1) | WO1999038877A2 (en) |
YU (1) | YU44900A (en) |
Families Citing this family (55)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6514949B1 (en) | 1994-07-11 | 2003-02-04 | University Of Virginia Patent Foundation | Method compositions for treating the inflammatory response |
YU44900A (en) | 1998-01-31 | 2003-01-31 | Glaxo Group Limited | 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives |
DE69910213T2 (en) | 1998-06-23 | 2004-07-01 | Glaxo Group Ltd., Greenford | 2- (PURIN-9-YL) -TETRAHYDROFURAN-3,4-DIOL DERIVATIVES |
GB9813565D0 (en) * | 1998-06-23 | 1998-08-19 | Glaxo Group Ltd | Chemical compounds |
GB9813554D0 (en) | 1998-06-23 | 1998-08-19 | Glaxo Group Ltd | Chemical compounds |
GB9813540D0 (en) * | 1998-06-23 | 1998-08-19 | Glaxo Group Ltd | Chemical compounds |
US6232297B1 (en) | 1999-02-01 | 2001-05-15 | University Of Virginia Patent Foundation | Methods and compositions for treating inflammatory response |
US7427606B2 (en) | 1999-02-01 | 2008-09-23 | University Of Virginia Patent Foundation | Method to reduce inflammatory response in transplanted tissue |
US7378400B2 (en) | 1999-02-01 | 2008-05-27 | University Of Virginia Patent Foundation | Method to reduce an inflammatory response from arthritis |
GB0022695D0 (en) | 2000-09-15 | 2000-11-01 | Pfizer Ltd | Purine Derivatives |
GB0104555D0 (en) * | 2001-02-23 | 2001-04-11 | Glaxo Group Ltd | New Therapeutic method |
GB2372742A (en) | 2001-03-03 | 2002-09-04 | Univ Leiden | C2,5'-Disubstituted and N6,C2,5'-trisubstituted adenosine derivatives and their different uses |
US20040162422A1 (en) * | 2001-03-20 | 2004-08-19 | Adrian Hall | Chemical compounds |
WO2003029264A2 (en) | 2001-10-01 | 2003-04-10 | University Of Virginia Patent Foundation | 2-propynyl adenosine analogs having a2a agonist activity and compositions thereof |
GB0206657D0 (en) * | 2002-03-21 | 2002-05-01 | Glaxo Group Ltd | Novel intermediate and process |
GB0206655D0 (en) * | 2002-03-21 | 2002-05-01 | Glaxo Group Ltd | Novel process |
AR044519A1 (en) | 2003-05-02 | 2005-09-14 | Novartis Ag | DERIVATIVES OF PIRIDIN-TIAZOL AMINA AND PIRIMIDIN-TIAZOL AMINA |
US7465715B2 (en) * | 2003-12-29 | 2008-12-16 | Can-Fite Biopharma, Ltd. | Method for treatment of multiple sclerosis |
GB0401334D0 (en) | 2004-01-21 | 2004-02-25 | Novartis Ag | Organic compounds |
TWI346109B (en) * | 2004-04-30 | 2011-08-01 | Otsuka Pharma Co Ltd | 4-amino-5-cyanopyrimidine derivatives |
GB0411056D0 (en) | 2004-05-18 | 2004-06-23 | Novartis Ag | Organic compounds |
AR049384A1 (en) | 2004-05-24 | 2006-07-26 | Glaxo Group Ltd | PURINA DERIVATIVES |
WO2006028618A1 (en) | 2004-08-02 | 2006-03-16 | University Of Virginia Patent Foundation | 2-polycyclic propynyl adenosine analogs with modified 5'-ribose groups having a2a agonist activity |
WO2006023272A1 (en) | 2004-08-02 | 2006-03-02 | University Of Virginia Patent Foundation | 2-polycyclic propynyl adenosine analogs having a2a agonist activity |
EP1778712B1 (en) | 2004-08-02 | 2013-01-30 | University Of Virginia Patent Foundation | 2-propynyl adenosine analogs with modified 5'-ribose groups having a2a agonist activity |
GB0424284D0 (en) | 2004-11-02 | 2004-12-01 | Novartis Ag | Organic compounds |
GB0426164D0 (en) | 2004-11-29 | 2004-12-29 | Novartis Ag | Organic compounds |
GB0510390D0 (en) | 2005-05-20 | 2005-06-29 | Novartis Ag | Organic compounds |
GB0514809D0 (en) | 2005-07-19 | 2005-08-24 | Glaxo Group Ltd | Compounds |
US7910708B2 (en) | 2005-10-21 | 2011-03-22 | Novartis Ag | Anti-IL13 human antibodies |
GB0601951D0 (en) | 2006-01-31 | 2006-03-15 | Novartis Ag | Organic compounds |
KR20080110925A (en) * | 2006-04-21 | 2008-12-19 | 노파르티스 아게 | Purine derivatives for use as adenosin a2a receptor agonists |
EP1889846A1 (en) * | 2006-07-13 | 2008-02-20 | Novartis AG | Purine derivatives as A2a agonists |
DE602007013441D1 (en) | 2006-09-29 | 2011-05-05 | Novartis Ag | PYRAZOLOPYRIMIDINE AS PI3K LIPID KINASE INHIBITOR |
CA2667962A1 (en) | 2006-10-30 | 2008-05-08 | Novartis Ag | Heterocyclic compounds as antiinflammatory agents |
PL2231642T3 (en) | 2008-01-11 | 2014-04-30 | Novartis Ag | Pyrimidines as kinase inhibitors |
PT2391366E (en) | 2009-01-29 | 2013-02-05 | Novartis Ag | Substituted benzimidazoles for the treatment of astrocytomas |
US8389526B2 (en) | 2009-08-07 | 2013-03-05 | Novartis Ag | 3-heteroarylmethyl-imidazo[1,2-b]pyridazin-6-yl derivatives |
EP2464649A1 (en) | 2009-08-12 | 2012-06-20 | Novartis AG | Heterocyclic hydrazone compounds and their uses to treat cancer and inflammation |
NZ598220A (en) | 2009-08-17 | 2014-02-28 | Intellikine Llc | Heterocyclic compounds and uses thereof |
CA2771432A1 (en) | 2009-08-20 | 2011-02-24 | Novartis Ag | Heterocyclic oxime compounds |
WO2012034095A1 (en) | 2010-09-09 | 2012-03-15 | Irm Llc | Compounds and compositions as trk inhibitors |
UY33597A (en) | 2010-09-09 | 2012-04-30 | Irm Llc | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF THE TRK |
JP2014505088A (en) | 2011-02-10 | 2014-02-27 | ノバルティス アーゲー | [1,2,4] Triazolo [4,3-b] pyridazine compounds as C-MET tyrosine kinase inhibitors |
JP5808826B2 (en) | 2011-02-23 | 2015-11-10 | インテリカイン, エルエルシー | Heterocyclic compounds and uses thereof |
US9102671B2 (en) | 2011-02-25 | 2015-08-11 | Novartis Ag | Compounds and compositions as TRK inhibitors |
UY34329A (en) | 2011-09-15 | 2013-04-30 | Novartis Ag | TRIAZOLOPIRIDINE COMPOUNDS |
US9174994B2 (en) | 2011-11-23 | 2015-11-03 | Intellikine, Llc | Enhanced treatment regimens using mTor inhibitors |
CN104245701A (en) | 2012-04-03 | 2014-12-24 | 诺华有限公司 | Combination with tyrosine kinase inhibitors and use thereof |
EP2968340A4 (en) | 2013-03-15 | 2016-08-10 | Intellikine Llc | Combination of kinase inhibitors and uses thereof |
TW201605450A (en) | 2013-12-03 | 2016-02-16 | 諾華公司 | Combination of Mdm2 inhibitor and BRAF inhibitor and their use |
CN106414446A (en) | 2014-03-13 | 2017-02-15 | 新加坡科技研究局 | Fused pyrimidine-based hydroxamate derivatives |
WO2016011658A1 (en) | 2014-07-25 | 2016-01-28 | Novartis Ag | Combination therapy |
KR20170036037A (en) | 2014-07-31 | 2017-03-31 | 노파르티스 아게 | Combination therapy |
TW202140550A (en) | 2020-01-29 | 2021-11-01 | 瑞士商諾華公司 | Methods of treating an inflammatory or obstructive airway disease using anti-tslp antibody |
Family Cites Families (66)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE768925A (en) | 1970-06-30 | 1971-11-03 | Takeda Chemical Industries Ltd | ADENOSINE DERIVATIVES AND METHOD OF PREPARATION |
DE2034785A1 (en) | 1970-07-14 | 1972-01-20 | Boehnnger Mannheim GmbH, 6800 Mann heim Waldhof | Adenosine 5 carboxylic acid derivatives |
US4224438A (en) | 1970-07-14 | 1980-09-23 | Boehringer Mannheim Gmbh | Adenosine-5'-carboxylic acid amides |
CA1019727A (en) | 1971-03-18 | 1977-10-25 | Abbott Laboratories | Adenosine-5'-carboxylic acid amides |
BE789773A (en) | 1971-10-08 | 1973-04-06 | Schering Ag | ADENOSINES N6 -SUBSTITUTED AND THEIR PROCESS FOR |
US3864483A (en) | 1972-03-22 | 1975-02-04 | Abbott Lab | Adenosine-5{40 -carboxylic acid amides |
CA1082695A (en) | 1972-04-10 | 1980-07-29 | Francis E. Fischer | Process for preparing adenosine-5'-carboxamides |
US3966917A (en) | 1974-07-30 | 1976-06-29 | Abbott Laboratories | Platelet aggregation inhibitors |
US4146715A (en) | 1975-08-27 | 1979-03-27 | Burroughs Wellcome Co. | 2-amido-9-(2-acyloxyethoxymethyl)hypoxanthines |
DE2621470A1 (en) | 1976-05-14 | 1977-12-01 | Pharma Waldhof Gmbh & Co | Nucleoside carboxylic acid nitriles and derivs. - prepd. from a (5')-(O)-tosylated or halogenated nucleoside and a metal cyanide or alpha:alkali acetic acid |
US4167565A (en) | 1976-11-08 | 1979-09-11 | Abbott Laboratories | Adenosine-5'-carboxamides and method of use |
AU8379182A (en) | 1981-06-04 | 1982-12-09 | Procter & Gamble Company, The | Composition of salicylates and purine derivatives |
JPS58167599A (en) | 1982-03-29 | 1983-10-03 | Tanabe Seiyaku Co Ltd | Adenosine derivative and its preparation |
JPS58174322A (en) | 1982-04-07 | 1983-10-13 | Tanabe Seiyaku Co Ltd | Agent for promoting fibrinolysis |
CA1239397A (en) | 1983-08-01 | 1988-07-19 | James A. Bristol | N.sup.6-substituted adenosines |
DE3406533A1 (en) | 1984-02-23 | 1985-08-29 | Boehringer Mannheim Gmbh, 6800 Mannheim | USE OF ADENOSINE DERIVATIVES AS ANTIALLERGICA AND MEDICINAL PRODUCTS CONTAINING THEM |
US4496643A (en) | 1984-03-23 | 1985-01-29 | Eastman Kodak Company | Two-component dry electrostatic developer composition containing onium charge control agent |
EP0300144A3 (en) | 1984-04-18 | 1989-09-27 | Whitby Research Incorporated | N-6 alkyl substituted adenosine derivatives as cardiac vasodilators |
US5310731A (en) * | 1984-06-28 | 1994-05-10 | Whitby Research, Inc. | N-6 substituted-5'-(N-substitutedcarboxamido)adenosines as cardiac vasodilators and antihypertensive agents |
US4663313A (en) | 1984-10-26 | 1987-05-05 | Warner-Lambert Company | N6 -tricyclic adenosines for treating hypertension |
AU575438B2 (en) | 1984-10-26 | 1988-07-28 | Warner-Lambert Company | N6 - substituted deoxyribose analogues of adenosines |
US5258380A (en) | 1985-06-24 | 1993-11-02 | Janssen Pharmaceutica N.V. | (4-piperidinylmethyl and -hetero)purines |
US4738954A (en) | 1985-11-06 | 1988-04-19 | Warner-Lambert Company | Novel N6 -substituted-5'-oxidized adenosine analogs |
US4755594A (en) | 1986-01-31 | 1988-07-05 | Warner-Lambert Company | N6 -substituted adenosines |
US5106837A (en) | 1988-03-16 | 1992-04-21 | The Scripps Research Institute | Adenosine derivatives with therapeutic activity |
JPH0696534B2 (en) | 1986-04-25 | 1994-11-30 | ヘキストジヤパン株式会社 | Anti-dementia agent |
US4767747A (en) | 1986-08-28 | 1988-08-30 | Warner-Lambert Company | Method for treating congestive heart failure with N6 -acenaphthyl adenosine |
WO1988003147A1 (en) | 1986-10-31 | 1988-05-05 | Warner-Lambert Company | Selected n6-substituted adenosines having selective a2 binding activity |
WO1988003148A2 (en) | 1986-10-31 | 1988-05-05 | Warner-Lambert Company | Heteroaromatic derivatives of adenoside |
HU198950B (en) | 1986-12-15 | 1989-12-28 | Sandoz Ag | Process for producing new furanuronic acid derivatives and pharmaceutical compositions comprising such compounds |
US4968697A (en) | 1987-02-04 | 1990-11-06 | Ciba-Geigy Corporation | 2-substituted adenosine 5'-carboxamides as antihypertensive agents |
FI880405A (en) * | 1987-02-04 | 1988-08-05 | Ciba Geigy Ag | Adenosine-5'-KARBOXAMIDDERIVAT. |
US4962194A (en) | 1987-04-02 | 1990-10-09 | Warner-Lambert Company | Method of preparing 51,N6-disubstituted adenosines from inosines |
US5219840A (en) | 1987-04-06 | 1993-06-15 | Sandoz Ltd. | Antihypertensive 9-(2,N6 -disubstituted adenyl) ribofuranuronic acid derivatives |
LU87181A1 (en) | 1987-04-06 | 1988-11-17 | Sandoz Sa | NOVEL DERIVATIVES OF FURANNURONIC ACID, THEIR PREPARATION AND THEIR USE AS MEDICAMENTS |
US5021574A (en) | 1988-03-03 | 1991-06-04 | Ortho Pharmaceutical Corporation | 6-substituted purinyl piperazine derivatives |
JPH0725785B2 (en) | 1989-01-11 | 1995-03-22 | 日本臓器製薬株式会社 | Adenosine derivative and pharmaceutical composition containing the compound as an active ingredient |
GB8920534D0 (en) | 1989-09-11 | 1989-10-25 | Wellcome Found | Antiviral compounds |
US5055569A (en) | 1989-10-19 | 1991-10-08 | G. D. Searle & Co. | N-(6)-substituted adenosine compounds |
EP0423777A3 (en) | 1989-10-19 | 1991-09-25 | G.D. Searle & Co. | Method of treating gastrointestinal motility disorders |
MY104575A (en) | 1989-12-22 | 1994-04-30 | The Wellcome Foundation Ltd | Therapeutic nucleosides. |
US5140015A (en) | 1990-02-20 | 1992-08-18 | Whitby Research, Inc. | 2-aralkoxy and 2-alkoxy adenosine derivatives as coronary vasodilators and antihypertensive agents |
US5280015A (en) | 1990-09-05 | 1994-01-18 | The United States Of America As Represented By The Department Of Health And Human Services | 2-substituted adenosines and 2-substituted adenosine 5'-carboxamides |
ES2095960T3 (en) | 1990-09-25 | 1997-03-01 | Rhone Poulenc Rorer Int | COMPOUNDS THAT HAVE ANTI-HYPERTENSIVE AND ANTI-ISCHEMICAL PROPERTIES. |
ZA923640B (en) | 1991-05-21 | 1993-02-24 | Iaf Biochem Int | Processes for the diastereoselective synthesis of nucleosides |
FR2685918B1 (en) | 1992-01-08 | 1995-06-23 | Union Pharma Scient Appl | NOVEL ADENOSINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. |
FR2687678B1 (en) | 1992-01-31 | 1995-03-31 | Union Pharma Scient Appl | NOVEL ADENOSINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. |
IT1254915B (en) | 1992-04-24 | 1995-10-11 | Gloria Cristalli | ADENOSINE DERIVATIVES FOR ACTIVITY A2 AGONIST |
US5424297A (en) | 1992-04-27 | 1995-06-13 | University Of Virginia Alumni Patents Foundation | Adenosine dextran conjugates |
WO1994002497A1 (en) | 1992-07-15 | 1994-02-03 | The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Sulfo-derivatives of adenosine |
GB9301000D0 (en) | 1993-01-20 | 1993-03-10 | Glaxo Group Ltd | Chemical compounds |
CA2154681A1 (en) | 1993-02-03 | 1994-08-18 | Mark David Erion | Adenosine kinase inhibitors comprising lyxofuranosyl derivatives |
EP0708781B1 (en) | 1993-07-13 | 2001-10-04 | THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, Department of Health and Human Services | A 3 adenosine receptor agonists |
US5446046A (en) | 1993-10-28 | 1995-08-29 | University Of Florida Research Foundation | A1 adenosine receptor agonists and antagonists as diuretics |
WO1995018817A1 (en) | 1994-01-07 | 1995-07-13 | Laboratoires Upsa | Novel adenosine derivatives, preparation methods therefor, and pharmaceutical compositions containing same |
GB9414193D0 (en) * | 1994-07-14 | 1994-08-31 | Glaxo Group Ltd | Compounds |
GB9414208D0 (en) | 1994-07-14 | 1994-08-31 | Glaxo Group Ltd | Compounds |
AU3255097A (en) | 1996-07-05 | 1998-02-02 | Novo Nordisk A/S | Novel (n)-alkoxyadenine derivatives acting as cytokine inhibitors |
UA51716C2 (en) | 1996-07-08 | 2002-12-16 | Авентіс Фармасьютікалз Продактс Інк. | combinations possessing hypotensive, cardioprotective, anti-ishemic, and antilipolytic agents, a pharmaceutical composition and METHOD OF TREATMENT |
WO1998016539A1 (en) | 1996-10-14 | 1998-04-23 | Novo Nordisk A/S | Novel therapeutically active adenosine derivatives |
FR2757518B1 (en) | 1996-12-23 | 1999-06-11 | Hoechst Marion Roussel Inc | NOVEL ERYTHROMYCIN DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICAMENTS |
TW528755B (en) | 1996-12-24 | 2003-04-21 | Glaxo Group Ltd | 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives |
YU44900A (en) | 1998-01-31 | 2003-01-31 | Glaxo Group Limited | 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives |
CO4990969A1 (en) | 1998-02-14 | 2000-12-26 | Glaxo Group Ltd | DERIVATIVES OF 2- (PURIN-9-IL) -TETRAHYDROFURAN-3,4-DIOL |
DE69910213T2 (en) | 1998-06-23 | 2004-07-01 | Glaxo Group Ltd., Greenford | 2- (PURIN-9-YL) -TETRAHYDROFURAN-3,4-DIOL DERIVATIVES |
GB9813535D0 (en) | 1998-06-23 | 1998-08-19 | Glaxo Group Ltd | Chemical compounds |
-
1998
- 1998-01-31 YU YU44900A patent/YU44900A/en unknown
-
1999
- 1999-01-28 PE PE1999000060A patent/PE20000280A1/en not_active Application Discontinuation
- 1999-01-28 CO CO99004721A patent/CO4980872A1/en unknown
- 1999-01-28 AR ARP990100336A patent/AR014508A1/en not_active Application Discontinuation
- 1999-01-29 AP APAP/P/2000/001875A patent/AP2000001875A0/en unknown
- 1999-01-29 SK SK1119-2000A patent/SK11192000A3/en unknown
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