ID18417A - INHIBITOR DENTAL METALOPROTEASE - Google Patents

INHIBITOR DENTAL METALOPROTEASE

Info

Publication number
ID18417A
ID18417A IDP972998A ID972998A ID18417A ID 18417 A ID18417 A ID 18417A ID P972998 A IDP972998 A ID P972998A ID 972998 A ID972998 A ID 972998A ID 18417 A ID18417 A ID 18417A
Authority
ID
Indonesia
Prior art keywords
metaloprotease
dental
inhibitor
inhibitor dental
dental metaloprotease
Prior art date
Application number
IDP972998A
Other languages
Indonesian (id)
Inventor
Almstead Neil Gregory
Bradley Rimma Sandler
Marlin Ii John Emory
De Biswanath
Garrett Garry Steven
Mciver John Mcmillan
Taiwo Yetunde Olabisi
Wang Zhe
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of ID18417A publication Critical patent/ID18417A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/46Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
    • C07D207/48Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/92Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
    • C07D211/96Sulfur atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Confectionery (AREA)
  • Pyrrole Compounds (AREA)
  • Cosmetics (AREA)
IDP972998A 1996-08-28 1997-08-28 INHIBITOR DENTAL METALOPROTEASE ID18417A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2474696P 1996-08-28 1996-08-28

Publications (1)

Publication Number Publication Date
ID18417A true ID18417A (en) 1998-04-09

Family

ID=21822181

Family Applications (1)

Application Number Title Priority Date Filing Date
IDP972998A ID18417A (en) 1996-08-28 1997-08-28 INHIBITOR DENTAL METALOPROTEASE

Country Status (20)

Country Link
US (1) US6121272A (en)
EP (1) EP0923547A1 (en)
JP (1) JP2000516954A (en)
KR (1) KR20000035921A (en)
CN (1) CN1228767A (en)
AU (1) AU4074097A (en)
BR (1) BR9712792A (en)
CA (1) CA2263914A1 (en)
CO (1) CO5420196A1 (en)
CZ (1) CZ62499A3 (en)
HU (1) HUP0000616A2 (en)
ID (1) ID18417A (en)
IL (1) IL128665A0 (en)
NO (1) NO990896L (en)
PE (1) PE109298A1 (en)
PL (1) PL331803A1 (en)
SK (1) SK24899A3 (en)
TR (1) TR199900401T2 (en)
WO (1) WO1998008814A1 (en)
ZA (1) ZA977697B (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999006340A2 (en) 1997-07-31 1999-02-11 The Procter & Gamble Company Sulfonylamino substituted hydroxamic acid derivatives as metalloprotease inhibitors
RU2208609C2 (en) 1998-02-04 2003-07-20 Новартис Аг Sulfonylamino-derivatives that inhibit activity of metalloproteinase decomposing matrix
US6410580B1 (en) 1998-02-04 2002-06-25 Novartis Ag Sulfonylamino derivatives which inhibit matrix-degrading metalloproteinases
US6846478B1 (en) 1998-02-27 2005-01-25 The Procter & Gamble Company Promoting whole body health
EP1084106A1 (en) 1998-06-03 2001-03-21 GPI NIL Holdings, Inc. N-linked sulfonamides of heterocyclic carboxylic acids or carboxylic acid isosteres
WO2000017162A1 (en) 1998-09-21 2000-03-30 Takeda Chemical Industries, Ltd. Novel thiol derivatives, process for producing the same and utilization thereof
EP1165501A1 (en) 1999-03-03 2002-01-02 The Procter & Gamble Company Alkenyl- and alkynyl-containing metalloprotease inhibitors
NZ513830A (en) 1999-03-03 2001-09-28 Procter & Gamble Dihetero-substituted metalloprotease inhibitors
WO2001010837A1 (en) * 1999-08-05 2001-02-15 The Procter & Gamble Company Multivalent sulfonamides
WO2001010838A1 (en) * 1999-08-05 2001-02-15 The Procter & Gamble Company Multivalent compounds
CN1536989A (en) 2000-06-30 2004-10-13 Oral compositions comprising host-respones modulating agent for promoting whole body health
US8283135B2 (en) 2000-06-30 2012-10-09 The Procter & Gamble Company Oral care compositions containing combinations of anti-bacterial and host-response modulating agents
EP1303485A1 (en) 2000-07-19 2003-04-23 F. Hoffmann-La Roche Ag Pyrrolidine derivatives as inhibitors of endothelin-converting enzyme
JP3983662B2 (en) * 2000-07-19 2007-09-26 エフ.ホフマン−ラ ロシュ アーゲー Pyrimidine derivatives
WO2002008185A1 (en) * 2000-07-19 2002-01-31 F. Hoffmann-La Roche Ag Pyrrolidine derivatives as metalloprotease inhibitors
FR2819252A1 (en) * 2001-01-11 2002-07-12 Servier Lab Pyrrolidine hydroxamic acid derivatives, useful as metalloprotease inhibitors in the treatment of cancers, rheumatic disorders or neuropathological degenerative disorders, e.g. cerebral ischemia or epilepsy
MXPA03011095A (en) * 2001-05-29 2005-04-28 Guilford Pharm Inc Method for treating nerve injury caused by surgery.
EP1581488B1 (en) * 2002-12-19 2009-09-16 Vertex Pharmaceuticals Incorporated Inhibitors of tace
US7897776B2 (en) 2007-04-23 2011-03-01 Salutria Pharmaceuticals Llc Sulfonamide containing compounds for treatment of inflammatory disorders
CN106905183B (en) * 2017-02-24 2018-07-31 三峡大学 A kind of amino-containing ɑ-acyloxy amide carbonyl class derivative, preparation method and applications

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3501489A (en) * 1966-01-21 1970-03-17 American Home Prod 1-phenylsulfonyl-2-(2-thiazolin-2-yl-oxy and thiol) pyrrolidines
US4695575A (en) * 1984-11-13 1987-09-22 Janssen Pharmaceutica, N.V. 4-[(bicycle heterocyclyl)-methyl and -hetero]-piperidines
IL74140A (en) * 1984-04-10 1988-05-31 Robins Co Inc A H Substituted n-((amino)alkyl)-1-pyrrolidine,-1-piperidine and-1-homopiperidine-carboxamides and pharmaceutical compositions containing them
US4595700A (en) * 1984-12-21 1986-06-17 G. D. Searle & Co. Thiol based collagenase inhibitors
GB8515934D0 (en) * 1985-06-24 1985-07-24 Janssen Pharmaceutica Nv (4-piperidinomethyl and-hetero)purines
IT1215590B (en) * 1987-06-29 1990-02-14 Roussel Maestretti Spa DERIVATIVES OF 1-BENZENE SULPHONYL 2-OCO 5-ALCHYLTIO PYROLIDINE, THEIR PROCEDURE OF PREPARATION AND THEIR USE AS MEDICINAL SUBSTANCES.
GB8814813D0 (en) * 1988-06-22 1988-07-27 Beecham Group Plc Novel compounds
DE4011172A1 (en) * 1990-04-06 1991-10-10 Degussa COMPOUNDS FOR CONTROLLING PLANT DISEASES
ES2069137T3 (en) * 1990-07-30 1995-05-01 Takeda Chemical Industries Ltd DERIVATIVES OF IMIDAZOPYRIDINE AND ITS USE.
JPH05125029A (en) * 1991-11-06 1993-05-21 Yamanouchi Pharmaceut Co Ltd New amide compound or its salt
US6090785A (en) * 1992-10-15 2000-07-18 Merck & Co., Inc. Substituted N-carboxyalkylpeptidyl derivatives as antidegenerative agents
US5455258A (en) * 1993-01-06 1995-10-03 Ciba-Geigy Corporation Arylsulfonamido-substituted hydroxamic acids
US5470834A (en) * 1993-10-06 1995-11-28 Florida State University Sulfoximine and suldodiimine matrix metalloproteinase inhibitors
US5455262A (en) * 1993-10-06 1995-10-03 Florida State University Mercaptosulfide metalloproteinase inhibitors
GB2303850B (en) * 1994-06-22 1998-06-10 British Biotech Pharm Metalloproteinase inhibitors
BR9609744A (en) * 1995-07-31 1999-03-02 Shionogi & Co Pyrrolidine derivatives having a2 phospholipase inhibitory activity
JP2000502330A (en) * 1995-12-08 2000-02-29 アグロン・ファーマシュウティカルズ・インコーポレーテッド Metalloproteinase inhibitors, pharmaceutical compositions containing them and their use as medicaments, and methods and intermediates useful for their production

Also Published As

Publication number Publication date
BR9712792A (en) 1999-12-14
JP2000516954A (en) 2000-12-19
PE109298A1 (en) 1999-01-31
IL128665A0 (en) 2000-01-31
TR199900401T2 (en) 1999-05-21
EP0923547A1 (en) 1999-06-23
US6121272A (en) 2000-09-19
CN1228767A (en) 1999-09-15
CA2263914A1 (en) 1998-03-05
AU4074097A (en) 1998-03-19
CZ62499A3 (en) 1999-07-14
HUP0000616A2 (en) 2000-07-28
CO5420196A1 (en) 2004-07-30
KR20000035921A (en) 2000-06-26
ZA977697B (en) 1998-02-23
WO1998008814A1 (en) 1998-03-05
NO990896L (en) 1999-04-20
SK24899A3 (en) 2000-04-10
NO990896D0 (en) 1999-02-25
PL331803A1 (en) 1999-08-02

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