HUT68249A - 2,6-methano-2h-quinolizin derivative as 5-ht3-receptor and pharmaceutical composition containing it and process for producing thereof - Google Patents

2,6-methano-2h-quinolizin derivative as 5-ht3-receptor and pharmaceutical composition containing it and process for producing thereof

Info

Publication number
HUT68249A
HUT68249A HU9402436A HU9402436A HUT68249A HU T68249 A HUT68249 A HU T68249A HU 9402436 A HU9402436 A HU 9402436A HU 9402436 A HU9402436 A HU 9402436A HU T68249 A HUT68249 A HU T68249A
Authority
HU
Hungary
Prior art keywords
quinolizin
methano
receptor
derivative
producing
Prior art date
Application number
HU9402436A
Other languages
English (en)
Other versions
HU216831B (hu
HU9402436D0 (en
Inventor
Maurice W Gittos
Original Assignee
Merrell Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Pharma Inc filed Critical Merrell Pharma Inc
Publication of HU9402436D0 publication Critical patent/HU9402436D0/hu
Publication of HUT68249A publication Critical patent/HUT68249A/hu
Publication of HU216831B publication Critical patent/HU216831B/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/18Bridged systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HU9402436A 1992-02-24 1993-02-03 Eljárás 5-HT3-receptor antagonista 2,6-metano-2H-kinolizin-származék és az ezt tartalmazó gyógyszerkészítmény előállítására HU216831B (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP92400474 1992-02-24

Publications (3)

Publication Number Publication Date
HU9402436D0 HU9402436D0 (en) 1994-10-28
HUT68249A true HUT68249A (en) 1995-06-28
HU216831B HU216831B (hu) 1999-09-28

Family

ID=8211614

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9402436A HU216831B (hu) 1992-02-24 1993-02-03 Eljárás 5-HT3-receptor antagonista 2,6-metano-2H-kinolizin-származék és az ezt tartalmazó gyógyszerkészítmény előállítására

Country Status (14)

Country Link
EP (1) EP0628043A1 (hu)
JP (1) JPH07504192A (hu)
KR (1) KR100287933B1 (hu)
AU (1) AU675060B2 (hu)
CA (1) CA2130563C (hu)
FI (1) FI105917B (hu)
HU (1) HU216831B (hu)
IL (1) IL104821A (hu)
MX (1) MX9300948A (hu)
NO (1) NO943101D0 (hu)
NZ (1) NZ249346A (hu)
TW (1) TW226374B (hu)
WO (1) WO1993017019A1 (hu)
ZA (1) ZA931146B (hu)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000048597A1 (en) 1999-02-18 2000-08-24 Novartis Ag Systemic use of 5-ht3 receptor antagonists against rheumatic inflammatory processes
US8518962B2 (en) 2005-03-07 2013-08-27 The University Of Chicago Use of opioid antagonists
US8524731B2 (en) 2005-03-07 2013-09-03 The University Of Chicago Use of opioid antagonists to attenuate endothelial cell proliferation and migration
US9662325B2 (en) 2005-03-07 2017-05-30 The University Of Chicago Use of opioid antagonists to attenuate endothelial cell proliferation and migration
CN101171010B (zh) 2005-03-07 2014-09-17 芝加哥大学 阿片样物质拮抗剂用于减少内皮细胞增殖和迁移的用途

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2080727T3 (es) * 1988-02-23 1996-02-16 Merrell Pharma Inc Uso de quinolizina y derivados de quinolizinona en la fabricacion de medicamentos.
EP0517984A1 (en) * 1991-06-11 1992-12-16 Merrell Dow Pharmaceuticals Inc. Derivatives of amide analogs of certain methano bridged quinolizines

Also Published As

Publication number Publication date
ZA931146B (en) 1993-09-14
HU216831B (hu) 1999-09-28
IL104821A (en) 1997-01-10
NO943101L (no) 1994-08-23
KR950700297A (ko) 1995-01-16
CA2130563A1 (en) 1993-09-02
EP0628043A1 (en) 1994-12-14
FI943872A (fi) 1994-08-23
FI943872A0 (fi) 1994-08-23
IL104821A0 (en) 1993-06-10
WO1993017019A1 (en) 1993-09-02
MX9300948A (es) 1993-08-01
HU9402436D0 (en) 1994-10-28
NZ249346A (en) 1995-10-26
AU675060B2 (en) 1997-01-23
KR100287933B1 (ko) 2001-05-02
FI105917B (fi) 2000-10-31
NO943101D0 (no) 1994-08-23
AU3603493A (en) 1993-09-13
JPH07504192A (ja) 1995-05-11
TW226374B (hu) 1994-07-11
CA2130563C (en) 1997-11-11

Similar Documents

Publication Publication Date Title
HU9400413D0 (en) Imidazoly-alcenoic acids, pharmaceutical compositions containing them, and process for producing them
HUP9900055A3 (en) 4-aryl-1-phenylalkyl-1,2,3,6-tetrahydropyridin -derivatives, process for producing them and pharmaceutical compositions containing them
HUT67375A (en) 1,5-benzodiazepine derivatives, pharmaceutical compositions containing them and process for their producing
HU9303252D0 (en) New thiopyrano-pyrrole derivatives, pharmaceutical compositions containing them and process for producing them
HUT53362A (en) Process for producing substituted 1,3-oxathiolans and pharmaceutical compositions comprising same
HUT73850A (en) 4-aza-androstenone derivative, pharmaceutical composition containing it, process for their production and intermediates
HUT64734A (en) Anthraquinone-derivativdes, process for preparing them and pharmaceutical compositions containing them
HUT62559A (en) Process for producing 1 alpha-hydroxy-d4-vitamins and pharmaceutical compositions comprising same
HUT54139A (en) Process for producing n-heteroaryl-4-quinolineamine derivatives and pharmaceutical compositions comprising such compounds
HUP9601034A3 (en) Aryl-alkyl-pyridazinone compounds, process for producing them, and pharmaceutical compositions containing them
HU9402187D0 (en) Heterocyclic compounds, process for producing them and pharmaceutical compositions containing them
HU9402292D0 (en) New baccatine-iii and 10-deacetyl-baccatine-iii derivatives, process for producing them and pharmaceutical compositions containing them as active component
HUT74615A (en) 2,3-cyclic-condensed-1,4-dihydro-pyridine derivatives, process for producing them and pharmaceutical compositions containing the same
HU9400934D0 (en) Thiadiazinone derivatives, pharmaceutical compositions containing them and process for producing them
HUT61548A (en) Process for producing indolonaphthyridine derivatives and pharmaceutical compositions comprising such compounds
HU9303376D0 (en) Process for producing alpha, omega-diaryl-alkane derivatives and pharmaceutical compositions containing them
HUT65768A (en) 17-beta-substituted 4-aza-androstane-derivatives and pharmaceutical compositions containing them and process for the production thereof
HU904661D0 (en) 14,17-alpha-etheno- and -ethano-esthatrienes and process for producing these compounds as well as pharmaceutical preparatives containing them
HUT68249A (en) 2,6-methano-2h-quinolizin derivative as 5-ht3-receptor and pharmaceutical composition containing it and process for producing thereof
HU9303322D0 (en) Pyrrole derivatives, process for producing them and pharmaceutical compositions containing them
HU9400909D0 (en) 1,2,5,6-terrahydro-pyridine derivative pharmaceutical compositions containing them and process for producing them
HUT71349A (en) Heteroaryl-piperidine derivatives, process for producing them and pharmaceutical compositions containing them
HUT63162A (en) Process for producing 1,4-benzodiazepine derivatives and pharmaceutical compositions comprising same
HUP0004177A3 (en) 4,5-diaryloxazole derivatives, pharmaceutical compositions containing them and process for producing them
HUT49870A (en) Process for producing new 1,2-dithiolo-3-thion-s-oxide derivatives and pharmaceutical compositions comprising these compounds

Legal Events

Date Code Title Description
GB9A Succession in title

Owner name: AVENTISUB II INC., US

Free format text: FORMER OWNER(S): AVENTIS INC., US; MERREL DOW PHARMACEUTICALS INC., US