HUT67611A - Process for producing optical active 1-(4-nitrophenyl)-4-methyl-7,8-methylen dioxi-3,4-dihydro-2h-2,2-benzodiazepine - Google Patents

Process for producing optical active 1-(4-nitrophenyl)-4-methyl-7,8-methylen dioxi-3,4-dihydro-2h-2,2-benzodiazepine

Info

Publication number
HUT67611A
HUT67611A HU9301922A HU9301922A HUT67611A HU T67611 A HUT67611 A HU T67611A HU 9301922 A HU9301922 A HU 9301922A HU 9301922 A HU9301922 A HU 9301922A HU T67611 A HUT67611 A HU T67611A
Authority
HU
Hungary
Prior art keywords
dioxi
methylen
benzodiazepine
nitrophenyl
dihydro
Prior art date
Application number
HU9301922A
Other languages
Hungarian (hu)
Other versions
HU9301922D0 (en
HU219777B (en
Inventor
Sandor Solyom
Imre Moravcsik
Tamas Hamori
Antal Simay
Peter Botka
Istvan Ling
Original Assignee
Gyogyszerkutato Intezet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gyogyszerkutato Intezet filed Critical Gyogyszerkutato Intezet
Priority to HU9301922A priority Critical patent/HU219777B/en
Publication of HU9301922D0 publication Critical patent/HU9301922D0/en
Priority to PCT/HU1994/000024 priority patent/WO1995001357A1/en
Priority to AU72363/94A priority patent/AU7236394A/en
Publication of HUT67611A publication Critical patent/HUT67611A/en
Publication of HU219777B publication Critical patent/HU219777B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HU9301922A 1993-07-02 1993-07-02 Optical active 1-(4-nitrophenyl)-4-methyl-7,8-methylen dioxi-3,4-dihydro-5h-2,3-benzodiazepine and process for producing it HU219777B (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
HU9301922A HU219777B (en) 1993-07-02 1993-07-02 Optical active 1-(4-nitrophenyl)-4-methyl-7,8-methylen dioxi-3,4-dihydro-5h-2,3-benzodiazepine and process for producing it
PCT/HU1994/000024 WO1995001357A1 (en) 1993-07-02 1994-06-30 Optically active 1-(4-nitrophenyl)-4-methyl-7,8-methylenedioxy-3,4-dihydro-5h-2,3-benzodiazepine and process for preparing same
AU72363/94A AU7236394A (en) 1993-07-02 1994-06-30 Optically active 1-(4-nitrophenyl)-4-methyl-7,8-methylenedioxy-3,4-dihydro-5h -2,3-benzodiazepine and process for preparing same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU9301922A HU219777B (en) 1993-07-02 1993-07-02 Optical active 1-(4-nitrophenyl)-4-methyl-7,8-methylen dioxi-3,4-dihydro-5h-2,3-benzodiazepine and process for producing it

Publications (3)

Publication Number Publication Date
HU9301922D0 HU9301922D0 (en) 1993-09-28
HUT67611A true HUT67611A (en) 1995-04-28
HU219777B HU219777B (en) 2001-07-30

Family

ID=10983751

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9301922A HU219777B (en) 1993-07-02 1993-07-02 Optical active 1-(4-nitrophenyl)-4-methyl-7,8-methylen dioxi-3,4-dihydro-5h-2,3-benzodiazepine and process for producing it

Country Status (3)

Country Link
AU (1) AU7236394A (en)
HU (1) HU219777B (en)
WO (1) WO1995001357A1 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TR199501072A2 (en) * 1994-08-31 1996-06-21 Lilly Co Eli Physical form of the dihydro-2,3-benzodiazepine derivative.
US6329364B1 (en) 1994-08-31 2001-12-11 Eli Lilly And Company Crystalline form of dihydro-2,3-benzodiazepine derivative
TR199501070A2 (en) * 1994-08-31 1996-06-21 Lilly Co Eli Crystalline form of the dihydro-2,3-benzodiazepine derivative.
WO1996006606A1 (en) * 1994-08-31 1996-03-07 Eli Lilly And Company Dihydro-2,3-benzodiazepine derivatives
TR199501071A2 (en) * 1994-08-31 1996-06-21 Lilly Co Eli Stereoselective process for producing dihydro-2,3-benzodiazepine derivatives.
DE69820081D1 (en) * 1997-08-12 2004-01-08 Egyt Gyogyszervegyeszeti Gyar 1-3 DIOXOLO / 4.5-H // 2,3-BENZODIAZEPINE DERIVATIVES AS AMPA / KAINATE RECEPTOR INHIBITORS
UA67749C2 (en) * 1997-08-12 2004-07-15 Егіш Дьйодьсердьяр Рт. 8-substituted-9h-1,3-dioxolo-[4,5-h][2,3]benzodiazepine being inhibitors of the ampa/kainite receptor
ATE324369T1 (en) 1999-02-15 2006-05-15 Eisai Co Ltd HETERODIAZINONE DERIVATIVES
HU227128B1 (en) * 1999-07-07 2010-07-28 Egyt Gyogyszervegyeszeti Gyar New 2,3-benzodiazepine derivatives
US6949571B2 (en) 2000-06-12 2005-09-27 Eisai Co., Ltd. 1,2-dihydropyridine compounds, process for preparation of the same and use thereof
US6649607B2 (en) 2001-05-18 2003-11-18 Vela Pharmaceuticals, Inc. Compositions and methods for treating or preventing convulsions or seizures
GB0129260D0 (en) 2001-12-06 2002-01-23 Eisai London Res Lab Ltd Pharmaceutical compositions and their uses
US6858605B2 (en) 2003-02-04 2005-02-22 Ivax Drug Research Institute, Ltd. Substituted 2,3-benzodiazepine derivatives
MY148809A (en) 2004-07-06 2013-05-31 Eisai R&D Man Co Ltd Crystals of 1,2-dihydropyridine compound and their production process
WO2020124090A1 (en) 2018-12-14 2020-06-18 Eisai R&D Management Co., Ltd. Aqueous based pharmaceutical formulations of 1,2-dihydropyridine compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU206719B (en) * 1990-12-21 1992-12-28 Gyogyszerkutato Intezet Process for producing 1-/4-acylamino-phenyl/-7,8-methylenedioxy-5h-2,3-benzodiazepine derivatives, acid addicional salts and pharmaceutical compositions containing them
HU219778B (en) * 1990-12-21 2001-07-30 Gyógyszerkutató Intézet Közös Vállalat Process for producing n-acyl-2,3-benzodiazepine derivatives, their acid additional salts and pharmaceutical compositions containing them and a grop of the compounds and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
HU9301922D0 (en) 1993-09-28
HU219777B (en) 2001-07-30
WO1995001357A1 (en) 1995-01-12
AU7236394A (en) 1995-01-24

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Legal Events

Date Code Title Description
DFD9 Temporary prot. cancelled due to non-payment of fee
DNF4 Restoration of lapsed final prot.
MM4A Lapse of definitive patent protection due to non-payment of fees