HUT63464A - Process for producing ciliary neurotrophic factor receptor - Google Patents

Process for producing ciliary neurotrophic factor receptor

Info

Publication number
HUT63464A
HUT63464A HU923772A HU377292A HUT63464A HU T63464 A HUT63464 A HU T63464A HU 923772 A HU923772 A HU 923772A HU 377292 A HU377292 A HU 377292A HU T63464 A HUT63464 A HU T63464A
Authority
HU
Hungary
Prior art keywords
cntf
neurotrophic factor
ciliary neurotrophic
factor receptor
relates
Prior art date
Application number
HU923772A
Other languages
Hungarian (hu)
Other versions
HU9203772D0 (en
Inventor
Samuel Davis
Stephen P Squinto
Mark E Furth
George D Yancopoulos
Original Assignee
Regeneron Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/676,647 external-priority patent/US5426177A/en
Application filed by Regeneron Pharma filed Critical Regeneron Pharma
Publication of HU9203772D0 publication Critical patent/HU9203772D0/en
Publication of HUT63464A publication Critical patent/HUT63464A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • C07K2319/41—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation containing a Myc-tag
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention relates to the ciliary neurotrophic factor (CNTF) receptor, and provides for CNTF receptor nucleic acid and amino acid sequences. It also relates to (i) assay systems for detecting CNTF activity; (ii) experimental model systems for studying the physiologic role of CNTF; (iii) diagnostic techniques for identifying CNTF-related neurologic conditions; (iv) therapeutic techniques for the treatment of CNTF-related neurologic and muscular conditions, and (v) methods for identifying molecules homologuous to CNTF and CNTFR.
HU923772A 1990-06-01 1991-06-03 Process for producing ciliary neurotrophic factor receptor HUT63464A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US53228590A 1990-06-01 1990-06-01
US07/676,647 US5426177A (en) 1990-06-01 1991-03-28 Ciliary neurotrophic factor receptor
US70067791A 1991-05-15 1991-05-15

Publications (2)

Publication Number Publication Date
HU9203772D0 HU9203772D0 (en) 1993-03-29
HUT63464A true HUT63464A (en) 1993-08-30

Family

ID=27415086

Family Applications (2)

Application Number Title Priority Date Filing Date
HU923772A HUT63464A (en) 1990-06-01 1991-06-03 Process for producing ciliary neurotrophic factor receptor
HU95P/P00737P HU211976A9 (en) 1990-06-01 1995-06-30 The ciliary neurotrophic factor receptor

Family Applications After (1)

Application Number Title Priority Date Filing Date
HU95P/P00737P HU211976A9 (en) 1990-06-01 1995-06-30 The ciliary neurotrophic factor receptor

Country Status (14)

Country Link
EP (1) EP0533846B1 (en)
JP (1) JP3266611B2 (en)
AT (1) ATE195341T1 (en)
AU (1) AU656732B2 (en)
CA (1) CA2084075C (en)
DE (1) DE69132361T2 (en)
FI (1) FI925457A0 (en)
HU (2) HUT63464A (en)
IE (1) IE911867A1 (en)
IL (1) IL98304A (en)
LV (1) LV10312B (en)
NO (1) NO924614L (en)
PT (1) PT97821A (en)
WO (1) WO1991019009A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5169764A (en) * 1990-08-08 1992-12-08 Regeneron Pharmaceuticals, Inc. Multitrophic and multifunctional chimeric neurotrophic factors, and nucleic acids and plasmids encoding the chimeras
US5360740A (en) * 1992-07-02 1994-11-01 Regeneron Pharmaceuticals, Inc. Assay system for degenerative muscle disease
US6472178B1 (en) 1998-02-27 2002-10-29 Regeneron Pharmaceuticals, Inc. Nucleic acids encoding a modified ciliary neurotrophic factor and method of making thereof
WO1994016721A1 (en) * 1993-01-29 1994-08-04 Regeneron Pharmaceuticals, Inc. Methods of treatment using ciliary neurotrophic factor
EP0717849B1 (en) * 1993-09-09 1998-05-20 Regeneron Pharmaceuticals, Inc. Assay systems using the cntf signal transduction pathway
DE4331297A1 (en) * 1993-09-15 1995-03-16 Henkel Kgaa Bar soaps
CA2409956A1 (en) * 2000-05-24 2001-11-29 Regeneron Pharmaceuticals, Inc. Use of ciliary neurotrophic factor
US20200297868A1 (en) * 2016-12-14 2020-09-24 University Of Cincinnati Methods and compositions for the treatment of als
CN113607714B (en) * 2021-10-08 2022-01-11 成都齐碳科技有限公司 Molecular film forming or characterizing device, apparatus, method and biochip

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5017375A (en) * 1982-11-24 1991-05-21 Baylor College Of Medicine Method to prepare a neurotrophic composition
US4923696A (en) * 1987-05-04 1990-05-08 Baylor College Of Medicine Method to prepare a neurotrophic composition
US5011914A (en) * 1989-01-05 1991-04-30 Collins Franklin D Purified ciliary neurotrophic factor
US4997929A (en) * 1989-01-05 1991-03-05 Synergen, Inc. Purified ciliary neurotrophic factor
IE903130A1 (en) * 1989-09-15 1991-03-27 Regeneron Pharma Ciliary neurotrophic factor
AU7291891A (en) * 1990-03-14 1991-09-19 Fidia S.P.A. Process for the isolation and expression of the human ciliary neuronotrophic factor by recombinant dna technology
IT1247150B (en) * 1991-01-21 1994-12-12 Fidia Spa PROCESS FOR THE SYNTHESIS AND PURIFICATION OF THE HUMAN NEURONOTROFICOCILIARY FACTOR (CNTF) FROM ESCHERICHIA COLI.

Also Published As

Publication number Publication date
DE69132361T2 (en) 2001-03-29
IL98304A0 (en) 1992-06-21
CA2084075C (en) 2005-08-16
EP0533846A4 (en) 1994-04-27
FI925457A (en) 1992-11-30
IE911867A1 (en) 1991-12-04
EP0533846B1 (en) 2000-08-09
ATE195341T1 (en) 2000-08-15
AU8233791A (en) 1991-12-31
CA2084075A1 (en) 1991-12-02
FI925457A0 (en) 1992-11-30
HU9203772D0 (en) 1993-03-29
NO924614L (en) 1993-01-21
JP3266611B2 (en) 2002-03-18
PT97821A (en) 1992-02-28
NO924614D0 (en) 1992-11-30
WO1991019009A1 (en) 1991-12-12
LV10312A (en) 1994-10-20
DE69132361D1 (en) 2000-09-14
AU656732B2 (en) 1995-02-16
HU211976A9 (en) 1996-01-29
IL98304A (en) 2008-08-07
EP0533846A1 (en) 1993-03-31
JPH06507062A (en) 1994-08-11
LV10312B (en) 1995-10-20

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Legal Events

Date Code Title Description
DFD9 Temporary protection cancelled due to non-payment of fee