HUT62938A - Process for obtaining high purity erythromycin from fermentation liquid - Google Patents

Process for obtaining high purity erythromycin from fermentation liquid

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Publication number
HUT62938A
HUT62938A HU314191A HU314191A HUT62938A HU T62938 A HUT62938 A HU T62938A HU 314191 A HU314191 A HU 314191A HU 314191 A HU314191 A HU 314191A HU T62938 A HUT62938 A HU T62938A
Authority
HU
Hungary
Prior art keywords
erythromycin
high purity
fermentation liquid
obtaining high
method involves
Prior art date
Application number
HU314191A
Other languages
Hungarian (hu)
Other versions
HU210190B (en
HU913141D0 (en
Inventor
Lajos Deak
Laszlo Zahoranszky
Laszlo Cseke
Attila Jakab
Imre Szekely
Zoltan Konyari
Vilmos Keri
Jozsefne Wittmann
Attilane Sanyo
Karoly Nagy
Janos Balint
Zsolt Agni
Original Assignee
Biogal Gyogyszergyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogal Gyogyszergyar filed Critical Biogal Gyogyszergyar
Priority to HU314191A priority Critical patent/HU210190B/en
Publication of HU913141D0 publication Critical patent/HU913141D0/en
Publication of HUT62938A publication Critical patent/HUT62938A/en
Publication of HU210190B publication Critical patent/HU210190B/en

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Abstract

The erythromycin liquid undergoes a two stage extraction at pH 8-12 and 5-25 deg.C with an alkaline organic water non-miscible solvent, e.g. i-butyl-acetate. After filtration the organic phase is mixed at 15-30 deg.C with a soln. of 1/6-1/8 w/w potassium thiocyanate in water or aq. acetic acid soln. to pH 6-7.5 producing erythromycine-thiocyanate, which is then separated by usual methods. - Another method involves heating lactic acid at 15-35 deg.C and pH 4.5-5.5 producing erythromycin lactate. Third method involves two stage extn. with an acid at pH 4-8 and temp. 5-25 deg.C.
HU314191A 1991-10-02 1991-10-02 Process for drawing-apart of erytromycine from fermentation-liquid HU210190B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
HU314191A HU210190B (en) 1991-10-02 1991-10-02 Process for drawing-apart of erytromycine from fermentation-liquid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU314191A HU210190B (en) 1991-10-02 1991-10-02 Process for drawing-apart of erytromycine from fermentation-liquid

Publications (3)

Publication Number Publication Date
HU913141D0 HU913141D0 (en) 1992-01-28
HUT62938A true HUT62938A (en) 1993-06-28
HU210190B HU210190B (en) 1995-02-28

Family

ID=10962764

Family Applications (1)

Application Number Title Priority Date Filing Date
HU314191A HU210190B (en) 1991-10-02 1991-10-02 Process for drawing-apart of erytromycine from fermentation-liquid

Country Status (1)

Country Link
HU (1) HU210190B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1054131C (en) * 1998-04-08 2000-07-05 浙江大学 Process for extracting ilotycin by two aqueous phase extracting process

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102659881B (en) * 2012-04-28 2014-12-17 安徽丰原发酵技术工程研究有限公司 Method for preparing erythromycin thiocyanate

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1054131C (en) * 1998-04-08 2000-07-05 浙江大学 Process for extracting ilotycin by two aqueous phase extracting process

Also Published As

Publication number Publication date
HU210190B (en) 1995-02-28
HU913141D0 (en) 1992-01-28

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Legal Events

Date Code Title Description
FH91 Appointment of a representative

Free format text: FORMER REPRESENTATIVE(S): INNOPATENT IPARJOGVEDELMI KFT.,, HU

Representative=s name: EMRI-PATENT IPARJOGVEDELMI KFT., HU

FH92 Termination of representative

Representative=s name: INNOPATENT IPARJOGVEDELMI KFT.,, HU

HC9A Change of name, address

Owner name: TEVA GYOGYSZERGYAR ZRT., HU

Free format text: FORMER OWNER(S): BIOGAL GYOGYSZERGYAR RT., HU