HUT62938A - Process for obtaining high purity erythromycin from fermentation liquid - Google Patents
Process for obtaining high purity erythromycin from fermentation liquidInfo
- Publication number
- HUT62938A HUT62938A HU314191A HU314191A HUT62938A HU T62938 A HUT62938 A HU T62938A HU 314191 A HU314191 A HU 314191A HU 314191 A HU314191 A HU 314191A HU T62938 A HUT62938 A HU T62938A
- Authority
- HU
- Hungary
- Prior art keywords
- erythromycin
- high purity
- fermentation liquid
- obtaining high
- method involves
- Prior art date
Links
Landscapes
- Saccharide Compounds (AREA)
Abstract
The erythromycin liquid undergoes a two stage extraction at pH 8-12 and 5-25 deg.C with an alkaline organic water non-miscible solvent, e.g. i-butyl-acetate. After filtration the organic phase is mixed at 15-30 deg.C with a soln. of 1/6-1/8 w/w potassium thiocyanate in water or aq. acetic acid soln. to pH 6-7.5 producing erythromycine-thiocyanate, which is then separated by usual methods. - Another method involves heating lactic acid at 15-35 deg.C and pH 4.5-5.5 producing erythromycin lactate. Third method involves two stage extn. with an acid at pH 4-8 and temp. 5-25 deg.C.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU314191A HU210190B (en) | 1991-10-02 | 1991-10-02 | Process for drawing-apart of erytromycine from fermentation-liquid |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU314191A HU210190B (en) | 1991-10-02 | 1991-10-02 | Process for drawing-apart of erytromycine from fermentation-liquid |
Publications (3)
Publication Number | Publication Date |
---|---|
HU913141D0 HU913141D0 (en) | 1992-01-28 |
HUT62938A true HUT62938A (en) | 1993-06-28 |
HU210190B HU210190B (en) | 1995-02-28 |
Family
ID=10962764
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU314191A HU210190B (en) | 1991-10-02 | 1991-10-02 | Process for drawing-apart of erytromycine from fermentation-liquid |
Country Status (1)
Country | Link |
---|---|
HU (1) | HU210190B (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1054131C (en) * | 1998-04-08 | 2000-07-05 | 浙江大学 | Process for extracting ilotycin by two aqueous phase extracting process |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102659881B (en) * | 2012-04-28 | 2014-12-17 | 安徽丰原发酵技术工程研究有限公司 | Method for preparing erythromycin thiocyanate |
-
1991
- 1991-10-02 HU HU314191A patent/HU210190B/en unknown
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1054131C (en) * | 1998-04-08 | 2000-07-05 | 浙江大学 | Process for extracting ilotycin by two aqueous phase extracting process |
Also Published As
Publication number | Publication date |
---|---|
HU210190B (en) | 1995-02-28 |
HU913141D0 (en) | 1992-01-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FH91 | Appointment of a representative |
Free format text: FORMER REPRESENTATIVE(S): INNOPATENT IPARJOGVEDELMI KFT.,, HU Representative=s name: EMRI-PATENT IPARJOGVEDELMI KFT., HU |
|
FH92 | Termination of representative |
Representative=s name: INNOPATENT IPARJOGVEDELMI KFT.,, HU |
|
HC9A | Change of name, address |
Owner name: TEVA GYOGYSZERGYAR ZRT., HU Free format text: FORMER OWNER(S): BIOGAL GYOGYSZERGYAR RT., HU |