HUT59680A - Process for producing new 17,17-didehydro-apovincamine derivatives nitro-substituted in the a ring and theyr salts - Google Patents
Process for producing new 17,17-didehydro-apovincamine derivatives nitro-substituted in the a ring and theyr saltsInfo
- Publication number
- HUT59680A HUT59680A HU831490A HU831490A HUT59680A HU T59680 A HUT59680 A HU T59680A HU 831490 A HU831490 A HU 831490A HU 831490 A HU831490 A HU 831490A HU T59680 A HUT59680 A HU T59680A
- Authority
- HU
- Hungary
- Prior art keywords
- salts
- ring
- theyr
- didehydro
- substituted
- Prior art date
Links
- 150000003839 salts Chemical class 0.000 title abstract 2
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 2
- OZDNDGXASTWERN-CTNGQTDRSA-N Apovincamine Chemical compound C1=CC=C2C(CCN3CCC4)=C5[C@@H]3[C@]4(CC)C=C(C(=O)OC)N5C2=C1 OZDNDGXASTWERN-CTNGQTDRSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000000141 anti-hypoxic effect Effects 0.000 abstract 1
- 229950006936 apovincamine Drugs 0.000 abstract 1
- OZDNDGXASTWERN-UHFFFAOYSA-N apovincamine Natural products C1=CC=C2C(CCN3CCC4)=C5C3C4(CC)C=C(C(=O)OC)N5C2=C1 OZDNDGXASTWERN-UHFFFAOYSA-N 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Novel 17,18-di:dehydro apo-vincamine derivs. substd. in ring `A' by a nitro gp. of formula (I) and their salts are active ingredients in antihypoxic pharmaceutical prepns. In formula (I) R1 is a nitro gp. in one of the posns. of 9, 10 or 11. R2 is a H atom, or 1-5C alkyl gp. with a proviso that when R2 is a Me gp. R1 occupies posn. 10 exclusively.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU831490A HU207076B (en) | 1990-12-18 | 1990-12-18 | Process for producing new 17,18-didehydroapovincamine derivatives substituted with a nitro group in ring a and salts thereof, as well as pharmaceutical compositions comprising same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU831490A HU207076B (en) | 1990-12-18 | 1990-12-18 | Process for producing new 17,18-didehydroapovincamine derivatives substituted with a nitro group in ring a and salts thereof, as well as pharmaceutical compositions comprising same |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| HU908314D0 HU908314D0 (en) | 1991-07-29 |
| HUT59680A true HUT59680A (en) | 1992-06-29 |
| HU207076B HU207076B (en) | 1993-03-01 |
Family
ID=10972532
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU831490A HU207076B (en) | 1990-12-18 | 1990-12-18 | Process for producing new 17,18-didehydroapovincamine derivatives substituted with a nitro group in ring a and salts thereof, as well as pharmaceutical compositions comprising same |
Country Status (1)
| Country | Link |
|---|---|
| HU (1) | HU207076B (en) |
-
1990
- 1990-12-18 HU HU831490A patent/HU207076B/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| HU908314D0 (en) | 1991-07-29 |
| HU207076B (en) | 1993-03-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| HMM4 | Cancellation of final prot. due to non-payment of fee |