HUT58755A - Process for producing daunomycin salts - Google Patents

Process for producing daunomycin salts

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Publication number
HUT58755A
HUT58755A HU393890A HU393890A HUT58755A HU T58755 A HUT58755 A HU T58755A HU 393890 A HU393890 A HU 393890A HU 393890 A HU393890 A HU 393890A HU T58755 A HUT58755 A HU T58755A
Authority
HU
Hungary
Prior art keywords
daunomycin
opt
alcohol
base
salts
Prior art date
Application number
HU393890A
Other languages
Hungarian (hu)
Other versions
HU903938D0 (en
HU206364B (en
Inventor
Andorne Uskert
Istvan Barta
Tibor Balogh
Gabor Ambrus
Karoly Albrecht
Gyoergy Pallos
Gyula Horvath
Lajos Ila
Istvan Ott
Kalman Koenczoel
Arpad Lazar
Attila Vincze
Imre Moravcsik
Zoltan Szeleczky
Antal Szabo
Original Assignee
Gyogyszerkutato Intezet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gyogyszerkutato Intezet filed Critical Gyogyszerkutato Intezet
Priority to HU393890A priority Critical patent/HU206364B/en
Publication of HU903938D0 publication Critical patent/HU903938D0/en
Publication of HUT58755A publication Critical patent/HUT58755A/en
Publication of HU206364B publication Critical patent/HU206364B/en

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Abstract

Daunomycin hydrogen halide salts of high purity are prepd. via crystalline daunomycin formate, from daunomycin base and formic acid or via the acetate. A salt is formed with anhydrous hydrogen-halide from the base, liberated in an non-polar solvent, opt. diluted by an 1-4C alcohol. This is opt. recrystallised from a chlorinated hydrocarbon and a 1-4C alcohol mixt. Conversely, daunomycin base liberated in aq. medium from its formate or acetate is dissolved in a non-polar solvent. The soln. is opt. diluted by an 1-4C alcohol and the salt is formed with anhydrous hydrogen-halide and opt. recrystallised from a mixt. of chlorinated hydrocarbon and 1-4C alcohol.(Dwg.0/1)
HU393890A 1990-06-21 1990-06-21 Process for producing daunomycin salts HU206364B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
HU393890A HU206364B (en) 1990-06-21 1990-06-21 Process for producing daunomycin salts

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU393890A HU206364B (en) 1990-06-21 1990-06-21 Process for producing daunomycin salts

Publications (3)

Publication Number Publication Date
HU903938D0 HU903938D0 (en) 1990-11-28
HUT58755A true HUT58755A (en) 1992-03-30
HU206364B HU206364B (en) 1992-10-28

Family

ID=10966149

Family Applications (1)

Application Number Title Priority Date Filing Date
HU393890A HU206364B (en) 1990-06-21 1990-06-21 Process for producing daunomycin salts

Country Status (1)

Country Link
HU (1) HU206364B (en)

Also Published As

Publication number Publication date
HU903938D0 (en) 1990-11-28
HU206364B (en) 1992-10-28

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Legal Events

Date Code Title Description
HMM4 Cancellation of final prot. due to non-payment of fee