HUT58098A - Process for producing quinolonecarboxylic acids substituted with bridged azabicyclic group substituted with amino group, as well as pharmaceutical compositions comprising same
- Google Patents
Process for producing quinolonecarboxylic acids substituted with bridged azabicyclic group substituted with amino group, as well as pharmaceutical compositions comprising same
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Publication number
HUT58098A
HUT58098AHU892136AHU213688AHUT58098AHU T58098 AHUT58098 AHU T58098AHU 892136 AHU892136 AHU 892136AHU 213688 AHU213688 AHU 213688AHU T58098 AHUT58098 AHU T58098A
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Application filed by PfizerfiledCriticalPfizer
Priority to HU892136ApriorityCriticalpatent/HU205756B/en
Priority claimed from PCT/US1988/002908external-prioritypatent/WO1990002123A1/en
Publication of HU892136D0publicationCriticalpatent/HU892136D0/en
Publication of HUT58098ApublicationCriticalpatent/HUT58098A/en
Publication of HU205756BpublicationCriticalpatent/HU205756B/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Plural Heterocyclic Compounds
(AREA)
Abstract
Quinoline derivs. of formula (I) and their pharmaceutically acceptable salts are new. R1=H, 1-6C alkyl or pharmaceutically acceptable cation; Y= cyclopropyl, ethyl, p-fluoro-phenyl; X= Hor F; or X-Y = OCH2CH(Me) or CH2CH(Me); R2 = a gp. of formula (a) R3=H or 1-4C alkyl. - Intermediates of formula (III) are new. Pref. R1=R3=X=H, and Y=cyclopropyl.
HU892136A1988-08-231988-08-23Process for producing quinolonecarboxylic acids substituted with azabicyclic group of bridged structure and substituted with amino group, as well as pharmaceutical compositions comprising same
HU205756B
(en)
Process for producing quinolonecarboxylic acids substituted with azabicyclic group of bridged structure and substituted with amino group, as well as pharmaceutical compositions comprising same
Process for producing quinolonecarboxylic acids substituted with azabicyclic group of bridged structure and substituted with amino group, as well as pharmaceutical compositions comprising same
Process for producing quinolonecarboxylic acids substituted with azabicyclic group of bridged structure and substituted with amino group, as well as pharmaceutical compositions comprising same
Process for producing 2,9-disubstituted-4h-pyrido(1,2-a)pyrimidine-4-one derivatives and pharmaceutical compositions comprising such compounds as active ingredient
Process for preparing piperidylidene dihydrodibenzo(a,d)cycloheptenes and aza derivatives thereof, compounds obtained by such process and the use of such compounds for preparing useful pharmaceutical compositions.
Process for producing quinolonecarboxylic acids substituted with bridged azabicyclic group substituted with amino group, as well as pharmaceutical compositions comprising same
Analogous Process for Preparing the Therapeutically Active Compound (S) -7- (3-Amino-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid, an in vivo readily cleavable lower alkyl ester or a pharmaceutically acceptable salt