HUT57779A - Process for producing new thiazetoquinoline-3-carboxylic acid derivatives
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Process for producing new thiazetoquinoline-3-carboxylic acid derivatives
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HUT57779A
HUT57779AHU645290AHU645290AHUT57779AHU T57779 AHUT57779 AHU T57779AHU 645290 AHU645290 AHU 645290AHU 645290 AHU645290 AHU 645290AHU T57779 AHUT57779 AHU T57779A
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Priority claimed from JP19129489Aexternal-prioritypatent/JPH0356489A/en
Application filed by Hokuriku PharmaceuticalfiledCriticalHokuriku Pharmaceutical
Publication of HU906452D0publicationCriticalpatent/HU906452D0/en
Publication of HUT57779ApublicationCriticalpatent/HUT57779A/en
Optically active thiazetoquinoline-3-carboxylic acid cpds. of formula (I) and their salts are new. (Where R1 = H or lower alkyl; R2 = F or Cl; R3 = H, lower alkanoyl, halogenated lower alkanoyl or the residue of a carboxylic acid ester; (asterisk) = an asymmetric C atom of S-or R- configuration). - 4 Cpds. (I), e.g. an optically active isomer of 7-((5)-3-amino-1-pyrrolidinyl) -8-chloro-6-fluoro-1-methyl-4-oxo -1H,4H-(1,3) thiazeto (3,2-a)quinoline-3-carboxylic acid (Ia) and an optically active isomer of 7-((R)-3-amino-1-pyrrolidinyl) -6,8 -difluoro-1-methyl-4-oxo-1H,4H-(1,3) thiazeto(3,2-a)quinoline-3-carb oxylic acid are specifically claimed.
HU645290A1989-07-261990-10-15Process for producing new thiazetoquinoline-3-carboxylic acid derivatives
HUT57779A
(en)
Process for the preparation of pharmacologically active 7- (3-substituted-1-pyrrolidinyl) -1-cyclopropyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid derivatives