HUT56584A - Process for purifying alkylated and hydroxyalkylated cyclodextrins and for reducing their unsubstituted cyclodextrin content - Google Patents
Process for purifying alkylated and hydroxyalkylated cyclodextrins and for reducing their unsubstituted cyclodextrin contentInfo
- Publication number
- HUT56584A HUT56584A HU178990A HU178990A HUT56584A HU T56584 A HUT56584 A HU T56584A HU 178990 A HU178990 A HU 178990A HU 178990 A HU178990 A HU 178990A HU T56584 A HUT56584 A HU T56584A
- Authority
- HU
- Hungary
- Prior art keywords
- alkylated
- cyclodextrins
- purifying
- reducing
- cyclodextrin content
- Prior art date
Links
- 229920000858 Cyclodextrin Polymers 0.000 title abstract 5
- 229940097362 cyclodextrins Drugs 0.000 title abstract 3
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical class O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 title 1
- 239000000969 carrier Substances 0.000 abstract 1
- 230000000536 complexating effect Effects 0.000 abstract 1
- 238000011109 contamination Methods 0.000 abstract 1
- 238000001802 infusion Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 230000003589 nefrotoxic effect Effects 0.000 abstract 1
- 239000003755 preservative agent Substances 0.000 abstract 1
- 239000008137 solubility enhancer Substances 0.000 abstract 1
- 238000001179 sorption measurement Methods 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
- 231100000419 toxicity Toxicity 0.000 abstract 1
- 230000001988 toxicity Effects 0.000 abstract 1
Landscapes
- Medicinal Preparation (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Toxicity caused by contamination and nephrotoxic action of unsubstd. cyclodextrins is eliminated when their concn. is reduced by adsorption or selective complexing below toxic levels in prepns. contg. alkylated or hydroxyalkylated cyclodextrins. These prepns. are administered in large doses, parenterally as injections or infusions. They contain 6, 7, or 8 membered substd. (alpha,beta, gamma)cyclodextrins as solubility enhancers, carriers or preservatives
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU178990A HUT56584A (en) | 1990-03-22 | 1990-03-22 | Process for purifying alkylated and hydroxyalkylated cyclodextrins and for reducing their unsubstituted cyclodextrin content |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU178990A HUT56584A (en) | 1990-03-22 | 1990-03-22 | Process for purifying alkylated and hydroxyalkylated cyclodextrins and for reducing their unsubstituted cyclodextrin content |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HU901789D0 HU901789D0 (en) | 1990-06-28 |
| HUT56584A true HUT56584A (en) | 1991-09-30 |
Family
ID=10956211
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU178990A HUT56584A (en) | 1990-03-22 | 1990-03-22 | Process for purifying alkylated and hydroxyalkylated cyclodextrins and for reducing their unsubstituted cyclodextrin content |
Country Status (1)
| Country | Link |
|---|---|
| HU (1) | HUT56584A (en) |
-
1990
- 1990-03-22 HU HU178990A patent/HUT56584A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HU901789D0 (en) | 1990-06-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| DGB9 | Succession in title of applicant |
Owner name: CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. |
|
| DFD9 | Temporary prot. cancelled due to non-payment of fee |