HUT55776A - Process for producing new derivatives of amides of apovincaminic acid and pharmaceutical compositions containing them - Google Patents

Process for producing new derivatives of amides of apovincaminic acid and pharmaceutical compositions containing them

Info

Publication number
HUT55776A
HUT55776A HU662889A HU662889A HUT55776A HU T55776 A HUT55776 A HU T55776A HU 662889 A HU662889 A HU 662889A HU 662889 A HU662889 A HU 662889A HU T55776 A HUT55776 A HU T55776A
Authority
HU
Hungary
Prior art keywords
acid
amides
pharmaceutical compositions
compositions containing
producing new
Prior art date
Application number
HU662889A
Other languages
Hungarian (hu)
Other versions
HU204268B (en
HU896628D0 (en
Inventor
Janos Kreidl
Laszlo Czibula
Gyoergy Visky
Bela Kiss
Egon Karpati
Laszlo Szporny
Eva Palosi
Dora Groo
Zsolt Szombathelyi
Adam Sarkadi
Istvan Laszlovszky
Aniko Gere
Mihaly Bodo
Erzsebet Lapis
Katalin Csomor
Judit Laszy
Zsolt Szentirmay
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Priority to HU662889A priority Critical patent/HU204268B/en
Publication of HU896628D0 publication Critical patent/HU896628D0/en
Publication of HUT55776A publication Critical patent/HUT55776A/en
Publication of HU204268B publication Critical patent/HU204268B/en

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Novel pharmaceutical apo-vincaminic-acid-amides and acid adduct salts of formula (I) - where R1 is not defined and R2 = 1-6C alkenyl, 1-6C hydroxyalkyl gp. or in this case a substd. aralkyl gp., are prepd by obtaining apo-vincamine-acid-chloride from apovincaminic-acid (II) and Vilsmeier complex. The acid-chloride reacts with amine of formula (III), opt. in the presence of an acid scavenger. Cpd. (I) is formed and opt. converted into the acid adduct salt.
HU662889A 1989-12-15 1989-12-15 Process for producing new apovincaminic-amide derivatives and pharmaceutical compositions containing them HU204268B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
HU662889A HU204268B (en) 1989-12-15 1989-12-15 Process for producing new apovincaminic-amide derivatives and pharmaceutical compositions containing them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU662889A HU204268B (en) 1989-12-15 1989-12-15 Process for producing new apovincaminic-amide derivatives and pharmaceutical compositions containing them

Publications (3)

Publication Number Publication Date
HU896628D0 HU896628D0 (en) 1990-02-28
HUT55776A true HUT55776A (en) 1991-06-28
HU204268B HU204268B (en) 1991-12-30

Family

ID=10971874

Family Applications (1)

Application Number Title Priority Date Filing Date
HU662889A HU204268B (en) 1989-12-15 1989-12-15 Process for producing new apovincaminic-amide derivatives and pharmaceutical compositions containing them

Country Status (1)

Country Link
HU (1) HU204268B (en)

Also Published As

Publication number Publication date
HU204268B (en) 1991-12-30
HU896628D0 (en) 1990-02-28

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Legal Events

Date Code Title Description
HMM4 Cancellation of final prot. due to non-payment of fee