HUT55776A - Process for producing new derivatives of amides of apovincaminic acid and pharmaceutical compositions containing them
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Process for producing new derivatives of amides of apovincaminic acid and pharmaceutical compositions containing them
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Publication number
HUT55776A
HUT55776AHU662889AHU662889AHUT55776AHU T55776 AHUT55776 AHU T55776AHU 662889 AHU662889 AHU 662889AHU 662889 AHU662889 AHU 662889AHU T55776 AHUT55776 AHU T55776A
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Application filed by Richter Gedeon VegyeszetfiledCriticalRichter Gedeon Vegyeszet
Priority to HU662889ApriorityCriticalpatent/HU204268B/en
Publication of HU896628D0publicationCriticalpatent/HU896628D0/en
Publication of HUT55776ApublicationCriticalpatent/HUT55776A/en
Publication of HU204268BpublicationCriticalpatent/HU204268B/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof
(AREA)
Nitrogen Condensed Heterocyclic Rings
(AREA)
Abstract
Novel pharmaceutical apo-vincaminic-acid-amides and acid adduct salts of formula (I) - where R1 is not defined and R2 = 1-6C alkenyl, 1-6C hydroxyalkyl gp. or in this case a substd. aralkyl gp., are prepd by obtaining apo-vincamine-acid-chloride from apovincaminic-acid (II) and Vilsmeier complex. The acid-chloride reacts with amine of formula (III), opt. in the presence of an acid scavenger. Cpd. (I) is formed and opt. converted into the acid adduct salt.
HU662889A1989-12-151989-12-15Process for producing new apovincaminic-amide derivatives and pharmaceutical compositions containing them
HU204268B
(en)
A procedure for preparing derivatives substituted in n 'of N- (trimetoxy-3,4,5) cinamoil-piperazine. (Machine-translation by Google Translate, not legally binding)
Legal Events
Date
Code
Title
Description
HMM4
Cancellation of final prot. due to non-payment of fee