HUT55409A - New process for producing corticosteroide-21-hemisuccinates - Google Patents
New process for producing corticosteroide-21-hemisuccinatesInfo
- Publication number
- HUT55409A HUT55409A HU508489A HU508489A HUT55409A HU T55409 A HUT55409 A HU T55409A HU 508489 A HU508489 A HU 508489A HU 508489 A HU508489 A HU 508489A HU T55409 A HUT55409 A HU T55409A
- Authority
- HU
- Hungary
- Prior art keywords
- hemisuccinates
- corticosteroide
- producing
- new process
- formula
- Prior art date
Links
Landscapes
- Steroid Compounds (AREA)
Abstract
Corticosteroid-21-hemisuccinates and corresponding alkali salts of formula (I) where R1 = H or OH, and R2 = H or R1 and R2 together = O; R3 = H or F; R4 = R5 = H or CH3; R6 = H or alkali metal atoms and dotted line represents an opt. double bond), are prepd. by acylation of cortico-steroids of formula (II) with succinic anhydride in an aliphatic tert.-alcohol in the presence of an organic base
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU508489A HU204844B (en) | 1989-09-27 | 1989-09-27 | New process for producing corticosteroid-21-hemisuccinates |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU508489A HU204844B (en) | 1989-09-27 | 1989-09-27 | New process for producing corticosteroid-21-hemisuccinates |
Publications (2)
Publication Number | Publication Date |
---|---|
HUT55409A true HUT55409A (en) | 1991-05-28 |
HU204844B HU204844B (en) | 1992-02-28 |
Family
ID=10969633
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU508489A HU204844B (en) | 1989-09-27 | 1989-09-27 | New process for producing corticosteroid-21-hemisuccinates |
Country Status (1)
Country | Link |
---|---|
HU (1) | HU204844B (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104650172A (en) * | 2015-03-25 | 2015-05-27 | 浙江仙琚制药股份有限公司 | Method for preparing methylprednisolone hemisuccinate |
CN109180763A (en) * | 2018-08-08 | 2019-01-11 | 河南利华制药有限公司 | A kind of production technology of hydrocortisone monomester succinate |
-
1989
- 1989-09-27 HU HU508489A patent/HU204844B/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
HU204844B (en) | 1992-02-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
HMM4 | Cancellation of final prot. due to non-payment of fee | ||
HMM4 | Cancellation of final prot. due to non-payment of fee |