HUT54388A - Process for producing new analogues of stimulator hormone for growth hormone secretion (grf) - Google Patents
Process for producing new analogues of stimulator hormone for growth hormone secretion (grf)Info
- Publication number
- HUT54388A HUT54388A HU893660A HU366089A HUT54388A HU T54388 A HUT54388 A HU T54388A HU 893660 A HU893660 A HU 893660A HU 366089 A HU366089 A HU 366089A HU T54388 A HUT54388 A HU T54388A
- Authority
- HU
- Hungary
- Prior art keywords
- arg
- ala
- ser
- grf
- ile
- Prior art date
Links
Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
Novel analogues of growth hormone secretion stimulating hormones (GRF) used in human medicine or as active ingredients in compsn. for animal husbandry are prepd. by customary synthetic prepn. methods in peptide chemistry. These hormones are peptides or peptide salts of formula (I). - H-Tyr-R2-As-Ala-Ile-Phe- Thr-Asn-Ser-Tyr-R11-Lys--Leu-Leu-Gln-Asp-Ile -R27-R28-Arg-Gaba-Y. - -R2= Ala. D-Ala; R11= Arg, D-Arg; R13= Val, Ile; R15= Gly, Leu, Phe, chemical bond; R27= Met, Nle; R28= Ser, D-Ser, Asn; Y= -OH, or -NH2 gp., provided that when R4 is Arg. R13 is Val. R15 is Gly, R27 is Nle, R28 is Ser; and Y is -OH or -NH2 gp. then R may only be D-Ala. (1pp Dwg.No.0/0)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU366089A HU205953B (en) | 1989-07-19 | 1989-07-19 | Process for producing new analogues of growth hormon secretion stimulating hormon and pharmaceutical and veterinaryc compositions containing them as active components |
US07/400,587 US5023322A (en) | 1988-08-31 | 1989-08-30 | Analogs of growth hormone releasing factor (GRF) and a method for the preparation thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU366089A HU205953B (en) | 1989-07-19 | 1989-07-19 | Process for producing new analogues of growth hormon secretion stimulating hormon and pharmaceutical and veterinaryc compositions containing them as active components |
Publications (2)
Publication Number | Publication Date |
---|---|
HUT54388A true HUT54388A (en) | 1991-02-28 |
HU205953B HU205953B (en) | 1992-07-28 |
Family
ID=10964957
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU366089A HU205953B (en) | 1988-08-31 | 1989-07-19 | Process for producing new analogues of growth hormon secretion stimulating hormon and pharmaceutical and veterinaryc compositions containing them as active components |
Country Status (1)
Country | Link |
---|---|
HU (1) | HU205953B (en) |
-
1989
- 1989-07-19 HU HU366089A patent/HU205953B/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
HU205953B (en) | 1992-07-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
HMM4 | Cancellation of final prot. due to non-payment of fee |