HUT46882A - Process for producing 3-bromo-/2s/-methyl-propionic acid - Google Patents

Process for producing 3-bromo-/2s/-methyl-propionic acid

Info

Publication number
HUT46882A
HUT46882A HU251487A HU251487A HUT46882A HU T46882 A HUT46882 A HU T46882A HU 251487 A HU251487 A HU 251487A HU 251487 A HU251487 A HU 251487A HU T46882 A HUT46882 A HU T46882A
Authority
HU
Hungary
Prior art keywords
methyl
bromo
propionic acid
acid
producing
Prior art date
Application number
HU251487A
Other languages
Hungarian (hu)
Other versions
HU197716B (en
Inventor
Janos Toempe
Laszlo Dobay
Endrene Petenyi
Mihaly Major
Janos Fischer
Laszlo Koncz
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Priority to HU251487A priority Critical patent/HU197716B/en
Publication of HUT46882A publication Critical patent/HUT46882A/en
Publication of HU197716B publication Critical patent/HU197716B/en

Links

Landscapes

  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Optically active 3-bromo-(2S) methyl-propionic acid is prepd. by resolution of racemic 3-bromo-2-methyl-propionic acid. The racemic cpd. is dissolved in a neutral solvent and (R)-3-(3'-4'-dimethoxy -phenyl) -2-methyl-2-amino- propionitrile is added as a resolving agent. The resulting diastereomer is sepd. by crystallisation and opt. recrystallised from a neutral organic solvent Finally 3-bromo-(2S)-methyl-propionic-acid is liberated by an acid from the diastereomer in an aq. medium. The resolving agent may be reused.
HU251487A 1987-06-02 1987-06-02 Process for production of 3-brome-/2s/-methil prophion acid HU197716B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
HU251487A HU197716B (en) 1987-06-02 1987-06-02 Process for production of 3-brome-/2s/-methil prophion acid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU251487A HU197716B (en) 1987-06-02 1987-06-02 Process for production of 3-brome-/2s/-methil prophion acid

Publications (2)

Publication Number Publication Date
HUT46882A true HUT46882A (en) 1988-12-28
HU197716B HU197716B (en) 1989-05-29

Family

ID=10959780

Family Applications (1)

Application Number Title Priority Date Filing Date
HU251487A HU197716B (en) 1987-06-02 1987-06-02 Process for production of 3-brome-/2s/-methil prophion acid

Country Status (1)

Country Link
HU (1) HU197716B (en)

Also Published As

Publication number Publication date
HU197716B (en) 1989-05-29

Similar Documents

Publication Publication Date Title
TNSN88012A1 (en) PROCESS FOR THE PREPARATION OF THE ALPHA DEXTROGYRAN ENANTIOMER (TETRAHYDRO-4,5,6,7 THIENO (3,2-C) PYRIDYL - 5) (CHLORO -2 PHENYL) METHYL ACETATE
RU94012931A (en) HYDRAZIDES 1H-INDOL-3-ACETIC ACID AS SPLA2 INHIBITORS
SE9501544D0 (en) New procedure
ES8601100A1 (en) Process for producing 3-(3,4-dihydroxyphenyl) serine.
ATE36517T1 (en) OPTICALLY ACTIVE ALPHA-SUBSTITUTED ARYLKETONES, PROCESSES FOR THEIR PREPARATION AND THEIR APPLICATION IN THE PREPARATION OF ALPHAARYLLKANCARBONSIDES.
IL73822A (en) Method of resolving bicyclic imino-carboxylic acid ester racemates,and novel intermediates therefor
RU92016289A (en) NEW 2-SACCHARINILMETHYL HETEROCYCLIC CARBOXYLATES, USEFUL FOR USE AS AN INHIBITORS OF PROTEOLYTIC ENZYMES, THEIR COMPOSITION AND METHOD OF THEIR USE
ATE239736T1 (en) PRODUCTION OF CLAVUNALATE SALTS
HUT46882A (en) Process for producing 3-bromo-/2s/-methyl-propionic acid
DE69523038T2 (en) METHOD FOR PRODUCING HIV PROTEASINHIBITORS
ATE288433T1 (en) IMPROVEMENTS RELATING TO THE PRODUCTION OF BETA-LACTAMES
DE69300471D1 (en) Process for the preparation of derivatives of epoxypropionic acid.
FR2665897B1 (en) PROCESS FOR THE CONVERSION OF ACID (BENZOYL-3 PHENYL) -2 PROPIONIC-R (-) TO THE S (+) ISOMER.
DE59208769D1 (en) Process for the enantioselective synthesis of 2 (R) -benzenesuccinic acid monoamide derivatives
NO891069D0 (en) PROCEDURE FOR PURIFICATION OF PURE ALFA-L-ASPARTYL-L-PHENYLALANINE METHYL ESTER (ALFA-APM).
ATE124048T1 (en) METHOD FOR PRODUCING BETA-LACTAMASE INHIBITORS.
SU1051096A1 (en) Process for preparing arylphosphonic acid dichloroanhydrides
FR2453864A1 (en) PROCESS FOR PRODUCING 6-B-AMIDINOPENICILLANIC ACID DERIVATIVES
ES2003994A6 (en) Optically active 2-chloro-12-(3-dimethylamino-2-methyl-propyl)-12H-dibenzo[d.g] [1,3,6] dioxazocines and a process for the preparation thereof
IT1231158B (en) PROCEDURE FOR THE OPTICAL RESOLUTION OF DRUG.
ATE175199T1 (en) METHOD FOR PRODUCING 2-SUBSTITUTED 5-CHLORIMIDAZOLE-4-CARBALDEHYDES
DE3874166D1 (en) METHOD FOR PRODUCING AND ISOLATING ESTERS OF (R) -2-HYDROXYPHENYLBUTTERIC ACID.
DK0535448T3 (en) Process and intermediates for the preparation of an antiviral agent containing a cyclobutyl group
EP0350038A3 (en) Enrichment of optical purity of 2-(4-aryloxyphenoxy) propionic acids by crystallization as hydrates
SE8403349D0 (en) HETEROCYCLIC ACETIC ACID ESTERS

Legal Events

Date Code Title Description
HU90 Patent valid on 900628
MM4A Lapse of definitive patent protection due to non-payment of fees