HUT41769A - Process for producing substituted pyridine derivatives - Google Patents
Process for producing substituted pyridine derivativesInfo
- Publication number
- HUT41769A HUT41769A HU864319A HU431986A HUT41769A HU T41769 A HUT41769 A HU T41769A HU 864319 A HU864319 A HU 864319A HU 431986 A HU431986 A HU 431986A HU T41769 A HUT41769 A HU T41769A
- Authority
- HU
- Hungary
- Prior art keywords
- pyridine derivatives
- substituted pyridine
- producing substituted
- producing
- derivatives
- Prior art date
Links
- 150000003222 pyridines Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB858525654A GB8525654D0 (en) | 1985-10-17 | 1985-10-17 | Chemical compounds |
GB868601667A GB8601667D0 (en) | 1986-01-23 | 1986-01-23 | Chemical compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
HUT41769A true HUT41769A (en) | 1987-05-28 |
HU196788B HU196788B (en) | 1989-01-30 |
Family
ID=26289898
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU864319A HU196788B (en) | 1985-10-17 | 1986-10-16 | Process for producing substituted dihydro-pyridine derivatives and pharmaceutical compositions containing them |
Country Status (16)
Country | Link |
---|---|
US (2) | US4906628A (en) |
EP (1) | EP0220044B1 (en) |
CN (1) | CN1009092B (en) |
AU (1) | AU586042B2 (en) |
DE (1) | DE3677316D1 (en) |
DK (1) | DK491186A (en) |
ES (1) | ES2031821T3 (en) |
FI (1) | FI864193A (en) |
GR (1) | GR3001555T3 (en) |
HU (1) | HU196788B (en) |
IL (1) | IL80296A (en) |
NO (1) | NO864126L (en) |
NZ (1) | NZ217931A (en) |
PH (1) | PH22428A (en) |
PT (1) | PT83530B (en) |
ZW (1) | ZW20586A1 (en) |
Families Citing this family (50)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4962110A (en) * | 1985-03-12 | 1990-10-09 | Smith Kline & French Laboratories Limited | Pyridazinone derivatives |
GB8610369D0 (en) * | 1986-04-28 | 1986-06-04 | Smith Kline French Lab | Heterocyclic compounds |
GB8621864D0 (en) * | 1986-09-11 | 1986-10-15 | Smith Kline French Lab | Chemical process |
GB8901836D0 (en) * | 1989-01-27 | 1989-03-15 | Sobio Lab | Compounds |
DE3913597A1 (en) * | 1989-04-25 | 1990-11-08 | Heumann Pharma Gmbh & Co | DIAZINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS |
US5202323A (en) * | 1990-04-25 | 1993-04-13 | Nissan Chemical Industries Ltd. | 5-arylmethylamino-6-oxy-substituted 3(2h)-pyridazinones |
DE69131268T2 (en) * | 1990-09-21 | 1999-12-30 | Rohm And Haas Co., Philadelphia | Dihydropyridazinone and pyridazinone as fungicides |
CN1038249C (en) * | 1991-08-28 | 1998-05-06 | 罗姆和哈斯公司 | Dihydropyridazinones, pyridazinones and related compounds as fungicides |
US5958926A (en) * | 1996-11-01 | 1999-09-28 | Nitromed, Inc. | Nitrosated and nitrosylated phosphodiesterase inhibitor compounds, compositions and their uses |
US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
DE102004011512B4 (en) | 2004-03-08 | 2022-01-13 | Boehringer Ingelheim Vetmedica Gmbh | Pharmaceutical preparation containing pimobendan |
EP1579862A1 (en) * | 2004-03-25 | 2005-09-28 | Boehringer Ingelheim Vetmedica Gmbh | Use of PDE III inhibitors for the reduction of heart size in mammals suffering from heart failure |
US8980894B2 (en) | 2004-03-25 | 2015-03-17 | Boehringer Ingelheim Vetmedica Gmbh | Use of PDE III inhibitors for the treatment of asymptomatic (occult) heart failure |
AU2006282896A1 (en) | 2005-08-26 | 2007-03-01 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation |
EP2258358A3 (en) | 2005-08-26 | 2011-09-07 | Braincells, Inc. | Neurogenesis with acetylcholinesterase inhibitor |
EP1940389A2 (en) | 2005-10-21 | 2008-07-09 | Braincells, Inc. | Modulation of neurogenesis by pde inhibition |
CA2625210A1 (en) | 2005-10-31 | 2007-05-10 | Braincells, Inc. | Gaba receptor mediated modulation of neurogenesis |
ZA200804550B (en) | 2005-11-09 | 2009-08-26 | Combinatorx Inc | Methods, compositions, and kits for the treatment of medical conditions |
ES2631879T3 (en) * | 2005-11-14 | 2017-09-05 | Boehringer Ingelheim Vetmedica Gmbh | Use of pimobendane for the treatment of asymptomatic (hidden) heart failure |
US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
CA2643199A1 (en) * | 2006-03-08 | 2007-09-13 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
US7678808B2 (en) | 2006-05-09 | 2010-03-16 | Braincells, Inc. | 5 HT receptor mediated neurogenesis |
EP2382975A3 (en) | 2006-05-09 | 2012-02-29 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
US20100009983A1 (en) * | 2006-05-09 | 2010-01-14 | Braincells, Inc. | 5 ht receptor mediated neurogenesis |
JP2010502722A (en) * | 2006-09-08 | 2010-01-28 | ブレインセルス,インコーポレイティド | Combinations containing 4-acylaminopyridine derivatives |
US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
WO2008036678A2 (en) * | 2006-09-19 | 2008-03-27 | Braincells, Inc. | Combination comprising a peroxisome proliferator activated receptor agent and a second neurogenic agent for treating a nervous system disorder, increasing neurodifferentiation and increasing neurogenesis |
EP1920785A1 (en) | 2006-11-07 | 2008-05-14 | Boehringer Ingelheim Vetmedica Gmbh | Liquid preparation comprising a complex of pimobendan and cyclodextrin |
US8034782B2 (en) | 2008-07-16 | 2011-10-11 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
US20100120694A1 (en) | 2008-06-04 | 2010-05-13 | Synergy Pharmaceuticals, Inc. | Agonists of Guanylate Cyclase Useful for the Treatment of Gastrointestinal Disorders, Inflammation, Cancer and Other Disorders |
US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
EP2527360B1 (en) | 2007-06-04 | 2015-10-28 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
MX2011005444A (en) | 2008-11-25 | 2011-06-09 | Boehringer Ingelheim Vetmed | PHOSPHODIESTERASE TYPE III (PDE III) INHIBITORS OR CA<sup>2+</sup>-SENSITIZING AGENTS FOR THE TREATMENT OF HYPERTROPHIC CARDIOMYOPATHY. |
WO2010099217A1 (en) | 2009-02-25 | 2010-09-02 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
CA2828346C (en) | 2011-03-01 | 2021-01-26 | Synergy Pharmaceuticals Inc. | Process of preparing guanylate cyclase c agonists |
WO2013106547A1 (en) | 2012-01-10 | 2013-07-18 | President And Fellows Of Harvard College | Beta-cell replication promoting compounds and methods of their use |
US10398705B2 (en) | 2012-03-15 | 2019-09-03 | Boehringer Ingelheim Vetmedica Gmbh | Pharmaceutical tablet formulation for the veterinary medical sector, method of production and use thereof |
EP3718557A3 (en) | 2013-02-25 | 2020-10-21 | Bausch Health Ireland Limited | Guanylate cyclase receptor agonist sp-333 for use in colonic cleansing |
EP2970384A1 (en) | 2013-03-15 | 2016-01-20 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
CA2905435A1 (en) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Compositions useful for the treatment of gastrointestinal disorders |
EA201592263A1 (en) | 2013-06-05 | 2016-05-31 | Синерджи Фармасьютикалз, Инк. | ULTRASCULAR AGONISTS OF GUANYLACYCLASE C, METHOD OF THEIR RECEIVING AND USING |
CN105377235A (en) | 2013-07-19 | 2016-03-02 | 勃林格殷格翰动物保健有限公司 | Preserved etherified cyclodextrin derivatives containing liquid aqueous pharmaceutical composition |
CA2920856A1 (en) | 2013-08-09 | 2015-02-12 | Ardelyx, Inc. | Ph modulating compounds for inhibiting gastrointestinal phosphate uptake |
CA3176466A1 (en) | 2013-12-04 | 2015-06-11 | Boehringer Ingelheim Vetmedica Gmbh | Improved pharmaceutical compositions of pimobendan |
US10537570B2 (en) | 2016-04-06 | 2020-01-21 | Boehringer Ingelheim Vetmedica Gmbh | Use of pimobendan for the reduction of heart size and/or the delay of onset of clinical symptoms in patients with asymptomatic heart failure due to mitral valve disease |
JOP20200024A1 (en) | 2017-08-04 | 2020-02-02 | Bayer Ag | Dihydrooxadiazinones |
EP3661917B1 (en) * | 2017-08-04 | 2022-05-11 | Bayer Aktiengesellschaft | 6-((3-trifluoromethyl)phenyl)-4,5-dihydropyridazin-3(2h)-one derivatives as pde3a and pde3b inhibitors for treating cancer |
JP2022533251A (en) | 2019-05-21 | 2022-07-21 | アルデリックス, インコーポレイテッド | Combinations to lower serum phosphate in patients |
DE102021105255B4 (en) * | 2021-03-04 | 2022-10-13 | Festo Se & Co. Kg | Device with components connected via a connection interface and method for connecting components |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL69407A (en) * | 1982-08-23 | 1987-10-20 | Warner Lambert Co | 2(1h)-pyridinones,their preparation and pharmaceutical compositions containing them |
DE3600891A1 (en) * | 1986-01-15 | 1987-07-16 | Bayer Ag | 1,8-BRIDGED 4-CHINOLON-3-CARBONIC ACIDS AND MEDICINAL PRODUCTS CONTAINING THEM |
-
1986
- 1986-10-13 ES ES198686307911T patent/ES2031821T3/en not_active Expired - Lifetime
- 1986-10-13 ZW ZW205/86A patent/ZW20586A1/en unknown
- 1986-10-13 EP EP86307911A patent/EP0220044B1/en not_active Expired - Lifetime
- 1986-10-13 DE DE8686307911T patent/DE3677316D1/en not_active Expired - Lifetime
- 1986-10-13 PT PT83530A patent/PT83530B/en not_active IP Right Cessation
- 1986-10-14 DK DK491186A patent/DK491186A/en not_active Application Discontinuation
- 1986-10-14 IL IL80296A patent/IL80296A/en unknown
- 1986-10-14 US US06/918,425 patent/US4906628A/en not_active Expired - Lifetime
- 1986-10-14 PH PH34365A patent/PH22428A/en unknown
- 1986-10-15 NZ NZ217931A patent/NZ217931A/en unknown
- 1986-10-16 HU HU864319A patent/HU196788B/en not_active IP Right Cessation
- 1986-10-16 FI FI864193A patent/FI864193A/en not_active IP Right Cessation
- 1986-10-16 CN CN86106546A patent/CN1009092B/en not_active Expired
- 1986-10-16 NO NO864126A patent/NO864126L/en unknown
- 1986-10-16 AU AU64166/86A patent/AU586042B2/en not_active Ceased
-
1989
- 1989-12-18 US US07/452,072 patent/US5066653A/en not_active Expired - Lifetime
-
1991
- 1991-03-05 GR GR91400270T patent/GR3001555T3/en unknown
Also Published As
Publication number | Publication date |
---|---|
EP0220044A2 (en) | 1987-04-29 |
NZ217931A (en) | 1989-04-26 |
NO864126D0 (en) | 1986-10-16 |
PH22428A (en) | 1988-09-12 |
NO864126L (en) | 1987-04-21 |
CN1009092B (en) | 1990-08-08 |
AU6416686A (en) | 1987-04-30 |
CN86106546A (en) | 1987-05-20 |
DE3677316D1 (en) | 1991-03-07 |
US5066653A (en) | 1991-11-19 |
FI864193A (en) | 1987-04-18 |
FI864193A0 (en) | 1986-10-16 |
ZW20586A1 (en) | 1988-05-25 |
AU586042B2 (en) | 1989-06-29 |
EP0220044B1 (en) | 1991-01-30 |
ES2031821T3 (en) | 1993-01-01 |
EP0220044A3 (en) | 1988-02-24 |
GR3001555T3 (en) | 1992-11-23 |
DK491186A (en) | 1987-04-18 |
US4906628A (en) | 1990-03-06 |
PT83530B (en) | 1989-05-31 |
DK491186D0 (en) | 1986-10-14 |
HU196788B (en) | 1989-01-30 |
PT83530A (en) | 1986-11-01 |
IL80296A (en) | 1990-06-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
HU90 | Patent valid on 900628 | ||
HMM4 | Cancellation of final prot. due to non-payment of fee |