HUT40650A - Process for production of derivatives of 1,12b dinobutitrail-octahydro-indolo /2,3a/-kynolin - Google Patents
Process for production of derivatives of 1,12b dinobutitrail-octahydro-indolo /2,3a/-kynolinInfo
- Publication number
- HUT40650A HUT40650A HU851517A HU151785A HUT40650A HU T40650 A HUT40650 A HU T40650A HU 851517 A HU851517 A HU 851517A HU 151785 A HU151785 A HU 151785A HU T40650 A HUT40650 A HU T40650A
- Authority
- HU
- Hungary
- Prior art keywords
- kynolin
- dinobutitrail
- indolo
- octahydro
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU851517A HU194220B (en) | 1985-04-19 | 1985-04-19 | Process for production of derivatives of 1,12 b disubstituated-octahydro-indolo /2,3-a/ quinolisine and medical compounds containing thereof |
US06/853,353 US4843080A (en) | 1985-04-19 | 1986-04-17 | 1,12-disubstituted octahydroindolo[2,3-]quinolizine derivatives, pharmaceutical compositions |
DK179986A DK179986A (da) | 1985-04-19 | 1986-04-18 | Racemiske og optisk aktive 1,12b-disubstituerede octahydroindolo(2,3-a)quinolizinderivater eller cis- og trans-isomere eller syreadditionssalte deraf, deres fremstilling og anvendelse som farmaceutika, mellemprodukter ved fremstillingen og disses fremstilling |
IL78536A IL78536A0 (en) | 1985-04-19 | 1986-04-18 | 1,12b-disubstituted octahydroindolo(2,3-a)quinolizine derivatives,their preparation and pharmaceutical compositions containing them |
CA000507053A CA1301171C (en) | 1985-04-19 | 1986-04-18 | 1,12b-disubstituted octahydroindolo ¬2,3-a| quinolizine derivatives, process for their preparation and pharmaceutical compositions containing them |
FI861642A FI861642A (fi) | 1985-04-19 | 1986-04-18 | Foerfarande foer framstaellning av 1,12b-disubstituerade oktahydroindolo/2,3-a/-kinolizinderivat. |
EP86302934A EP0202774A3 (en) | 1985-04-19 | 1986-04-18 | 1,12b-Disubstituted octahydroindolo [2,3-a]-Quinolizine derivatives |
AU56381/86A AU587025B2 (en) | 1985-04-19 | 1986-04-18 | 1,12b-disubstituted octahydroindolo (2,3-a)-quinolizine derivatives process for their preparation and pharmaceutical compositions containing them |
JP61088396A JPS61249985A (ja) | 1985-04-19 | 1986-04-18 | 1,12b−ニ置換オクタヒドロインドロ〔2,3−a〕キノリジン誘導体 |
ZA862942A ZA862942B (en) | 1985-04-19 | 1986-04-18 | 1,12b-disubstituted octahydroindolo(2,3-a)-quinolizine derivatives,process for their preparation and pharmaceutical compositions containing them |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU851517A HU194220B (en) | 1985-04-19 | 1985-04-19 | Process for production of derivatives of 1,12 b disubstituated-octahydro-indolo /2,3-a/ quinolisine and medical compounds containing thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
HUT40650A true HUT40650A (en) | 1987-01-28 |
HU194220B HU194220B (en) | 1988-01-28 |
Family
ID=10954837
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU851517A HU194220B (en) | 1985-04-19 | 1985-04-19 | Process for production of derivatives of 1,12 b disubstituated-octahydro-indolo /2,3-a/ quinolisine and medical compounds containing thereof |
Country Status (10)
Country | Link |
---|---|
US (1) | US4843080A (hu) |
EP (1) | EP0202774A3 (hu) |
JP (1) | JPS61249985A (hu) |
AU (1) | AU587025B2 (hu) |
CA (1) | CA1301171C (hu) |
DK (1) | DK179986A (hu) |
FI (1) | FI861642A (hu) |
HU (1) | HU194220B (hu) |
IL (1) | IL78536A0 (hu) |
ZA (1) | ZA862942B (hu) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU195214B (en) * | 1985-04-19 | 1988-04-28 | Richter Gedeon Vegyeszet | Process for producing 12b-substituted-1-(hydroxymethyl)-octahydro-indolo /2,3-a/ quinolizine derivatives and pharmaceutical preparations comprising these compounds |
HU194221B (en) * | 1985-04-19 | 1988-01-28 | Richter Gedeon Vegyeszet | Process for preparing novel octahydro-indolo/2,3-a/quinoline derivative and pharmaceutical comprising this compound |
ZA904311B (en) * | 1989-06-08 | 1991-04-24 | Duphar Int Res | Method of preparing n-oxo-tetrahydro-beta-carbolines |
WO2014124193A1 (en) | 2013-02-08 | 2014-08-14 | General Mills, Inc. | Reduced sodium food products |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3478051A (en) * | 1967-03-17 | 1969-11-11 | Sandoz Ag | Azecino- and azonino(5,4-b)indoles |
HU174502B (hu) * | 1976-12-30 | 1980-01-28 | Richter Gedeon Vegyeszet | Sposob poluchenija novykh proizvodnykh oktagidro-indolo/2,3-a/-khinolizina |
GB2009749B (en) * | 1977-11-25 | 1982-04-28 | Scras | Indolo(1,3-a)quinolizidines |
ZA786426B (en) * | 1977-11-25 | 1979-10-31 | Scras | New indulo(2,3-a)quinolizidines,preparation and therapeutic use |
HU178700B (en) * | 1978-02-10 | 1982-06-28 | Richter Gedeon Vegyeszet | Process for preparing 1,1-disubstituted octahydro-indolo/2,3-a/-quinolizines |
HU178402B (en) * | 1978-08-01 | 1982-04-28 | Richter Gedeon Vegyeszet | New process for producing okrahydro-indolo-square bracket-2,3-a-square bracket closed-quinolysines |
HU177732B (en) * | 1978-12-15 | 1981-12-28 | Richter Gedeon Vegyeszet | Process for producing 10-bromo-vincamine and acid additional salts thereof,and 10-bromo-14-epivincamine |
US4353911A (en) * | 1979-07-20 | 1982-10-12 | Andre Buzas | Indolo(2,3-a)quinolizidines, useful in increasing femoral and vertebral blood flow |
US4358452A (en) * | 1980-05-09 | 1982-11-09 | John Wyeth & Brother Limited | N-[1,2,3,4,6,7,12,12 α-octahydro-2H-indolo(2,3α)-quinolizinyl-2β-yl]alkane and benzyl sulfonamides and anti-hypertensive use thereof |
HU185305B (en) * | 1981-08-23 | 1985-01-28 | Richter Gedeon Vegyeszet | Process for preparing vincine and apovincine |
HU182380B (en) * | 1981-09-30 | 1983-12-28 | Richter Gedeon Vegyeszet | Process for producing esters of vincaminic acid |
EP0079411B1 (fr) * | 1981-11-18 | 1987-02-04 | Thal, Claude | Dérivés d'indoloquinolizine, leur procédé de préparation et leur application en thérapeutique |
HU195214B (en) * | 1985-04-19 | 1988-04-28 | Richter Gedeon Vegyeszet | Process for producing 12b-substituted-1-(hydroxymethyl)-octahydro-indolo /2,3-a/ quinolizine derivatives and pharmaceutical preparations comprising these compounds |
HU194221B (en) * | 1985-04-19 | 1988-01-28 | Richter Gedeon Vegyeszet | Process for preparing novel octahydro-indolo/2,3-a/quinoline derivative and pharmaceutical comprising this compound |
-
1985
- 1985-04-19 HU HU851517A patent/HU194220B/hu not_active IP Right Cessation
-
1986
- 1986-04-17 US US06/853,353 patent/US4843080A/en not_active Expired - Fee Related
- 1986-04-18 AU AU56381/86A patent/AU587025B2/en not_active Ceased
- 1986-04-18 EP EP86302934A patent/EP0202774A3/en not_active Withdrawn
- 1986-04-18 ZA ZA862942A patent/ZA862942B/xx unknown
- 1986-04-18 CA CA000507053A patent/CA1301171C/en not_active Expired - Fee Related
- 1986-04-18 IL IL78536A patent/IL78536A0/xx not_active IP Right Cessation
- 1986-04-18 DK DK179986A patent/DK179986A/da not_active Application Discontinuation
- 1986-04-18 FI FI861642A patent/FI861642A/fi not_active Application Discontinuation
- 1986-04-18 JP JP61088396A patent/JPS61249985A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
AU587025B2 (en) | 1989-08-03 |
FI861642A0 (fi) | 1986-04-18 |
DK179986D0 (da) | 1986-04-18 |
EP0202774A3 (en) | 1989-03-15 |
US4843080A (en) | 1989-06-27 |
CA1301171C (en) | 1992-05-19 |
FI861642A (fi) | 1986-10-20 |
ZA862942B (en) | 1987-03-25 |
JPS61249985A (ja) | 1986-11-07 |
DK179986A (da) | 1986-10-20 |
IL78536A0 (en) | 1986-08-31 |
HU194220B (en) | 1988-01-28 |
EP0202774A2 (en) | 1986-11-26 |
AU5638186A (en) | 1986-10-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
HU90 | Patent valid on 900628 | ||
HMM4 | Cancellation of final prot. due to non-payment of fee |