HUT40444A - Process for preparing antibacterial compounds and pharmaceutical compositions containing such compounds - Google Patents

Process for preparing antibacterial compounds and pharmaceutical compositions containing such compounds

Info

Publication number
HUT40444A
HUT40444A HU851546A HU154685A HUT40444A HU T40444 A HUT40444 A HU T40444A HU 851546 A HU851546 A HU 851546A HU 154685 A HU154685 A HU 154685A HU T40444 A HUT40444 A HU T40444A
Authority
HU
Hungary
Prior art keywords
compounds
pharmaceutical compositions
compositions containing
preparing antibacterial
optionally substituted
Prior art date
Application number
HU851546A
Other languages
Hungarian (hu)
Other versions
HU195966B (en
Inventor
Masahiri Kondo
Akio Miyake
Masahiko Fujino
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of HUT40444A publication Critical patent/HUT40444A/en
Publication of HU195966B publication Critical patent/HU195966B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Novel cephem compounds of general formula (I), wherein R1 represents and optionally amino group, R2 represents H or halogen, R3 represents H or an optionally substituted hydrocarbon residue, R4 represents H or methoxy, A represents an optionally substituted imidazol-l-yl group forming a fuzed ring at positions 2 and 3 or 3 and 4, and n represents 0 or 1. They have an excellent antibacterial activity.
HU851546A 1984-04-23 1985-04-22 Process for preparing antibacterial compounds and pharmaceutical compositions containing such compounds HU195966B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/JP1984/000212 WO1985004879A1 (en) 1984-04-23 1984-04-23 Cephem compounds

Publications (2)

Publication Number Publication Date
HUT40444A true HUT40444A (en) 1986-12-28
HU195966B HU195966B (en) 1988-08-29

Family

ID=13818317

Family Applications (1)

Application Number Title Priority Date Filing Date
HU851546A HU195966B (en) 1984-04-23 1985-04-22 Process for preparing antibacterial compounds and pharmaceutical compositions containing such compounds

Country Status (6)

Country Link
AT (1) ATE79882T1 (en)
DK (1) DK179985A (en)
HU (1) HU195966B (en)
MY (1) MY102089A (en)
WO (1) WO1985004879A1 (en)
ZA (1) ZA853017B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4496896A (en) * 1995-01-30 1996-08-21 Takeda Chemical Industries Ltd. Cephem compounds, their production and use

Also Published As

Publication number Publication date
WO1985004879A1 (en) 1985-11-07
MY102089A (en) 1992-03-31
ZA853017B (en) 1986-12-30
DK179985D0 (en) 1985-04-22
DK179985A (en) 1985-10-24
HU195966B (en) 1988-08-29
ATE79882T1 (en) 1992-09-15

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Legal Events

Date Code Title Description
HU90 Patent valid on 900628
HMM4 Cancellation of final prot. due to non-payment of fee