HUT36686A - Process for the production of new organic phosphoric acid-esters and pesticides containing such compounds as agent
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Process for the production of new organic phosphoric acid-esters and pesticides containing such compounds as agent
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HUT36686A
HUT36686AHU199484AHU199484AHUT36686AHU T36686 AHUT36686 AHU T36686AHU 199484 AHU199484 AHU 199484AHU 199484 AHU199484 AHU 199484AHU T36686 AHUT36686 AHU T36686A
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Application filed by Mitsubishi Chem IndfiledCriticalMitsubishi Chem Ind
Priority to HU199484ApriorityCriticalpatent/HUT36686A/en
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New organophosphoric acid ester of benzofuranols have formula (I) where R1 is alkyl; R2 is alkyl or thioalkyl; R3, R4 and R5 are each H, halogen, alkylthio, NO2, CN, alkyl, alkylsulphinyl, alkylsulphonyl or CF3, and X is O or S. A typical cpd. is O-ethyl-S-n-propyl-O- (2,3-dihydro-2,2-dimethyl -4-chloro-7-benzo-furanyl) thiophosphate. - Cpds. (I) are prepd. by reacting a phosphoric acid halide of formula (R'O)(R2)(X)P-Hal with a phenol of formula (II) in an inert solvent and in the presence of an acid-binding agent. Cpds. (I) having R2=1-3C alkylthio are obtd. by reacting a phosphate of formula (III) - (where M is alkali metal or - NH4+) with an alkyl halide of formula R2'-Hal (where R2' is 1-3C alkyl). Cpds. (I) where R2 is hal are obtd. by reacting a phosphoric acid ester halide of formula (IV) with an alkyl mercaptan of formula R2'SH. Cpds. (I) having alkylsulphinyl sulphonyl gps. are obtd. by oxidn. of the corresp. alkylthio-substd. cpds.
HU199484A1984-04-041984-04-04Process for the production of new organic phosphoric acid-esters and pesticides containing such compounds as agent
HUT36686A
(en)
New substituted cephalosporin sulfones as antiinflammatory and antidegenerative agents, pharmaceutical compositions containing the same and processes for making them