HUT34042A - Process for producing new cyclic oktapeptides of vasopressin antagonistic activity and pharmaceutical compositions containing them - Google Patents
Process for producing new cyclic oktapeptides of vasopressin antagonistic activity and pharmaceutical compositions containing themInfo
- Publication number
- HUT34042A HUT34042A HU84597A HU59784A HUT34042A HU T34042 A HUT34042 A HU T34042A HU 84597 A HU84597 A HU 84597A HU 59784 A HU59784 A HU 59784A HU T34042 A HUT34042 A HU T34042A
- Authority
- HU
- Hungary
- Prior art keywords
- oktapeptides
- pharmaceutical compositions
- compositions containing
- antagonistic activity
- producing new
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/16—Oxytocins; Vasopressins; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/15—Oxytocin or vasopressin; related peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
- Emergency Protection Circuit Devices (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/467,117 US4469679A (en) | 1983-02-16 | 1983-02-16 | Octapeptide vasopressin antagonists |
Publications (2)
Publication Number | Publication Date |
---|---|
HUT34042A true HUT34042A (en) | 1985-01-28 |
HU196227B HU196227B (en) | 1988-10-28 |
Family
ID=23854436
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU84597A HU196227B (en) | 1983-02-16 | 1984-02-15 | Process for producing new cyclic vasopressin antagonist peptides and pharmaceutics comprising the same |
Country Status (20)
Country | Link |
---|---|
US (2) | US4469679A (hu) |
EP (1) | EP0119705B1 (hu) |
JP (1) | JPS59155348A (hu) |
KR (1) | KR850001230A (hu) |
AT (1) | ATE46174T1 (hu) |
AU (1) | AU577778B2 (hu) |
DE (1) | DE3479664D1 (hu) |
DK (1) | DK65284A (hu) |
ES (2) | ES8606408A1 (hu) |
FI (1) | FI840577A (hu) |
GR (1) | GR81786B (hu) |
HU (1) | HU196227B (hu) |
IE (1) | IE56859B1 (hu) |
IL (1) | IL70944A (hu) |
NO (1) | NO840563L (hu) |
NZ (1) | NZ207106A (hu) |
PH (1) | PH20076A (hu) |
PT (1) | PT78094B (hu) |
ZA (1) | ZA841104B (hu) |
ZW (1) | ZW1884A1 (hu) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2708547A (en) * | 1950-07-19 | 1955-05-17 | Semt | Exhaust gas turbo-blowers for high supercharging rates and method of mounting same |
US4714696A (en) * | 1984-01-26 | 1987-12-22 | Medical College Of Ohio | Novel derivatives of arginine vasopressin antagonists |
US4649130A (en) * | 1984-01-26 | 1987-03-10 | Medical College Of Ohio | Novel derivatives of arginine vasopressin antagonists |
US4599324A (en) * | 1984-11-21 | 1986-07-08 | Smithkline Beckman Corporation | V1-vasopressin antagonists |
US4684716A (en) * | 1984-12-14 | 1987-08-04 | Smithkline Beckman Corporation | Polypeptide intermediates |
US4624943A (en) * | 1985-03-20 | 1986-11-25 | Smithkline Beckman Corporation | Aromatic basic-tailed vasopressin antagonists |
US4656248A (en) * | 1985-04-23 | 1987-04-07 | Smithkline Beckman Corporation | Cupric oxidation of 1,6-dimercapto-containing peptides |
US4711877A (en) * | 1985-09-18 | 1987-12-08 | Smithkline Beckman Corporation | 6-pen-vasopressin compounds |
US4742154A (en) * | 1985-10-23 | 1988-05-03 | Smithkline Beckman Corporation | GLN- or ASN-vasopressin compounds |
US4687758A (en) * | 1985-11-19 | 1987-08-18 | Smithkline Beckman Corporation | Des-proline-N-methylarginine vasopressins |
US4760052A (en) * | 1986-01-16 | 1988-07-26 | Smithkline Beckman Corporation | 1,6-dicarba-vasopressin compounds |
US4876243A (en) * | 1986-02-25 | 1989-10-24 | Smithkline Beckman Corporation | Vasopressin compounds |
US4717715A (en) * | 1986-06-23 | 1988-01-05 | Smithkline Beckman Corporation | ARG7 -ARG8 -vasopressin antagonists |
US4724229A (en) * | 1986-09-30 | 1988-02-09 | Smithkline Beckman Corporation | Arg-arg-arg-vasopressin antagonists |
US4766108A (en) * | 1986-12-04 | 1988-08-23 | Smith Kline Beckman Corporation | Tyr-Arg-vasopressin antagonists |
US4826813A (en) * | 1987-05-21 | 1989-05-02 | Smithkline Beckman Corporation | 4'-Methyl-β-mercapto-β,β-cyclopentamethylenepropionic acid vasopressin antagonists |
US5055448A (en) * | 1987-06-25 | 1991-10-08 | Medical College Of Ohio | Linear derivatives of arginine vasopressin antagonists |
JP2542241B2 (ja) * | 1988-08-12 | 1996-10-09 | 富士レビオ株式会社 | ペプチド |
US5051400A (en) * | 1990-06-28 | 1991-09-24 | Smithkline Beecham Corporation | Method of treating nausea and emesis related to motion sickness with vasopressin antagonists |
US6759384B1 (en) | 1994-04-26 | 2004-07-06 | Aventis Pharmaceuticals Inc. | Factor Xa inhibitors |
US5849510A (en) * | 1994-04-26 | 1998-12-15 | Selectide Corporation | Factor Xa inhibitors |
JP3655632B2 (ja) * | 1994-04-26 | 2005-06-02 | アベンティス・ファーマスーティカルズ・インコーポレイテッド | 第Xa因子インヒビター |
US6001809A (en) * | 1994-07-11 | 1999-12-14 | Elan Pharmaceuticals, Inc. | Inhibitors of leukocyte adhesion |
EP1950224A3 (en) * | 1998-03-09 | 2008-12-17 | Zealand Pharma A/S | Pharmacologically active peptide conjugates having a reduced tendency towards enzymatic hydrolysis |
US9375478B1 (en) | 2015-01-30 | 2016-06-28 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
US9750785B2 (en) | 2015-01-30 | 2017-09-05 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
US9687526B2 (en) | 2015-01-30 | 2017-06-27 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
US9744209B2 (en) | 2015-01-30 | 2017-08-29 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
US9925233B2 (en) | 2015-01-30 | 2018-03-27 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
US9937223B2 (en) | 2015-01-30 | 2018-04-10 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1246055A (en) * | 1980-03-24 | 1988-12-06 | Joseph H. Cort | N-.omega.-substituted hormonogens of vasopressin and its synthetic analogs |
US4367225A (en) * | 1981-03-24 | 1983-01-04 | The Medical College Of Ohio | Novel antagonists of the antidiuretic and/or vasopressor action of arginine vasopressin |
US4399125A (en) * | 1981-03-24 | 1983-08-16 | Maurice Manning | Novel antagonists of the antidiuretic action of arginine vasopressin |
US4643520A (en) * | 1983-03-10 | 1987-02-17 | Allied Corporation | Method of terminating fiber optic connector without polishing optical fiber |
-
1983
- 1983-02-16 US US06/467,117 patent/US4469679A/en not_active Expired - Fee Related
-
1984
- 1984-02-03 EP EP84300692A patent/EP0119705B1/en not_active Expired
- 1984-02-03 DE DE8484300692T patent/DE3479664D1/de not_active Expired
- 1984-02-03 AT AT84300692T patent/ATE46174T1/de active
- 1984-02-10 NZ NZ207106A patent/NZ207106A/en unknown
- 1984-02-13 PH PH30237A patent/PH20076A/en unknown
- 1984-02-13 IL IL70944A patent/IL70944A/xx unknown
- 1984-02-13 AU AU24534/84A patent/AU577778B2/en not_active Ceased
- 1984-02-13 GR GR73789A patent/GR81786B/el unknown
- 1984-02-13 ZW ZW18/84A patent/ZW1884A1/xx unknown
- 1984-02-13 PT PT78094A patent/PT78094B/pt not_active IP Right Cessation
- 1984-02-14 FI FI840577A patent/FI840577A/fi not_active Application Discontinuation
- 1984-02-14 DK DK65284A patent/DK65284A/da not_active Application Discontinuation
- 1984-02-15 NO NO840563A patent/NO840563L/no unknown
- 1984-02-15 JP JP59027986A patent/JPS59155348A/ja active Pending
- 1984-02-15 HU HU84597A patent/HU196227B/hu not_active IP Right Cessation
- 1984-02-15 IE IE352/84A patent/IE56859B1/en unknown
- 1984-02-15 ZA ZA841104A patent/ZA841104B/xx unknown
- 1984-02-15 ES ES529738A patent/ES8606408A1/es not_active Expired
- 1984-02-16 KR KR1019840000736A patent/KR850001230A/ko not_active Application Discontinuation
- 1984-06-26 US US06/624,542 patent/US4542124A/en not_active Expired - Fee Related
- 1984-09-12 ES ES535842A patent/ES535842A0/es active Granted
Also Published As
Publication number | Publication date |
---|---|
ZA841104B (en) | 1985-04-24 |
NZ207106A (en) | 1990-12-21 |
PT78094A (en) | 1984-03-01 |
IE56859B1 (en) | 1992-01-01 |
JPS59155348A (ja) | 1984-09-04 |
FI840577A (fi) | 1984-08-17 |
AU2453484A (en) | 1984-08-23 |
ATE46174T1 (de) | 1989-09-15 |
ES8600216A1 (es) | 1985-10-01 |
IE840352L (en) | 1984-08-16 |
DE3479664D1 (en) | 1989-10-12 |
PT78094B (en) | 1986-05-20 |
FI840577A0 (fi) | 1984-02-14 |
ES535842A0 (es) | 1985-10-01 |
EP0119705A2 (en) | 1984-09-26 |
IL70944A (en) | 1990-11-29 |
EP0119705A3 (en) | 1987-04-22 |
KR850001230A (ko) | 1985-03-16 |
ES8606408A1 (es) | 1986-04-01 |
US4542124A (en) | 1985-09-17 |
ES529738A0 (es) | 1986-04-01 |
HU196227B (en) | 1988-10-28 |
NO840563L (no) | 1984-08-17 |
AU577778B2 (en) | 1988-10-06 |
PH20076A (en) | 1986-09-18 |
GR81786B (hu) | 1984-12-12 |
EP0119705B1 (en) | 1989-09-06 |
DK65284A (da) | 1984-08-17 |
IL70944A0 (en) | 1984-05-31 |
US4469679A (en) | 1984-09-04 |
ZW1884A1 (en) | 1984-05-30 |
DK65284D0 (da) | 1984-02-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
HU90 | Patent valid on 900628 | ||
HMM4 | Cancellation of final prot. due to non-payment of fee |